[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-405305-105":59,"doc-detail-405305-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","guidelines-for-the-safe-prescription-and-administration-of-oral-bowel-cleansing-agents","Guidelines for the Safe Prescription and Administration of Oral Bowel-Cleansing Agents","","Oral bowel-cleansing preparations are used before colonic surgery and before endoscopic and radiological assessment to minimise faecal contamination. In February 2009, the UK National Patient Safety Agency issued a Rapid Response Report warning of potential harm linked to these preparations, describing one death and 218 safety incidents over five years. Consensus guidance outlines available oral agents, possible complications, and recommendations for selection and administration across different patient groups. Evidence is assessed using a modified GRADE approach, covering relative and absolute risks.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/guidelines-for-the-safe-prescription-and-administration-of-oral-bowel-cleansing-agents/405305/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/guidelines-for-the-safe-prescription-and-administration-of-oral-bowel-cleansing-agents/405305.png","ImageObject",300,407,{"name":92,"@type":93},"Aria","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":29},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why are oral bowel-cleansing agents used before colon-related procedures?","Question",{"text":112,"@type":113},"They are used before colonic surgery and endoscopic or radiological assessment to minimise faecal contamination during investigations and procedures.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What prompted these consensus guidelines?",{"text":117,"@type":113},"A February 2009 Rapid Response Report from the UK National Patient Safety Agency highlighted potential harm associated with oral bowel-cleansing preparations and the need for safeguards.",{"name":119,"@type":110,"acceptedAnswer":120},"What safeguards does the guidance emphasize for clinical assessment?",{"text":121,"@type":113},"It requires clinical assessment for contraindications and risks, clinician authorization, patient explanation on safe use, and a safe supply system for each patient.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},405305,1790722242,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":29,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":39,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":46,"preview_page_count":4},2336464648322,"https://ap-avatar.wpscdn.com/avatar/2200025388227c56fec?_k=1778556882303663488","Guidelines  \nConsensus guidelines for the safe prescription and administration of oral bowel-cleansing agents Andrew Connor, 1 Damian Tolan,2 Stephen Hughes,3 Nick Carr,4 Charles Tomson3  \n\u003C Additional appendices are published online only. To view these files please visit the journal online ([http://dx.doi.org/](http://dx.doi.org/)[ ](http://dx.doi.org/)[10.1136/gutjnl-2011-300861](10.1136/gutjnl-2011-300861)) . 1SpR, Dorset County Hospital, Dorchester, UK  \n2St James’ University Hospital, Leeds, UK  \n3Southmead Hospital, Bristol, UK  \n4Singleton Hospital, Swansea, UK  \nCorrespondence to Dr Stephen Hughes, 43 Kellaway Avenue, Bristol BS6 7XS, UK; [steve.hughes@nbt](steve.hughes@nbt). [nhs.uk](nhs.uk)  \nAccepted 2 May 2012  \nABSTRACT  \nOral bowel-cleansing preparations are used before colonic surgery and endoscopic and radiological assessment of the intestine to minimise faecal contamination. In February 2009, the UK National Patient Safety Agency issued a Rapid Response Report highlighting the potential risk of harm associated with the use of these preparations and instructing local NHS Trusts to implement safeguards to reduce this risk. This guidance has been prepared to help NHS Trusts to respond to these concerns, as the risk of complications is influenced by both individual patient risk factors and the choice of bowel preparation, for which definitive guidance was not previously available. This document provides an outline of the different available oral bowelcleansing agents and the complications that may arise. This is followed by recommendations for their use indifferent patient groups and circumstances. The recommendations are based on consensus between the authors, each of whom circulated drafts to members of their specialist society. The evidence for these recommendations has been assessed using the modified GRADE system. The recommendations cover the choice, administration and complications (relative and absolute) of the different oral bowel-cleansing agents, with specific guidance provided for different patient groups.  \nINTRODUCTION  \nOral bowel-cleansing preparations are used before colonic surgery and endoscopic and radiological assessment of large and small intestine to minimise faecal contamination. In general, these preparations are safe and well tolerated. However, in February 2009, the UK National Patient Safety Agency (NPSA) issued a Rapid Response Report alerting healthcare providers to the potential risk of harm associated with the use of oral bowel-cleansing preparations and reporting one death and 218 patient safety incidents occurring over a 5-year period.1 Six per cent of the 218 patient safety incidents resulted in moderate harm and one patient death was reported. These data are derived from a voluntary reporting system and, as such, are subject to bias: a proportion of incidents will not be reported, and those that are reported may underestimate severity (if reported before the full patient outcome is known) . The majority of these incidents were reported as relating to the administration (56%) and prescription (21%) of the oral bowel-cleansing agents. The manifestations of these patient safety incidents included harm asa result of prescription of bowel preparation to patients in whom there was a definite contraindication (eg, presence of ileostomy, bowel obstruc-  \ntion) or renal failure as a result of phosphate nephropathy, complications of hypovolaemia and electrolyte disturbances including hypokalaemia, hyponatraemia and hypermagnesaemia. Although there are no reliable estimates of the frequency of each of these complications, it is reasonable to put systems in place to reduce the risk of complications, so long as this response is proportionate and does not greatly add to the complexity or cost of investigation.  \nSCOPE  \nThe NPSA Report instructed NHS Trusts that safeguards should be implemented at a local level to reduce this risk, and specifically required that all NHS Trusts ensure that a clinical","cbCairJfCprFKGLa","https://ap.wps.com/l/cbCairJfCprFKGLa","pdf",112488,"English","# Guidelines\n## Scope and purpose\n## Evidence and consensus basis\n## Patient assessment and safeguards\n## Recommendations by patient group\n## Complications and risk management","[{\"question\":\"Why are oral bowel-cleansing agents used before colon-related procedures?\",\"answer\":\"They are used before colonic surgery and endoscopic or radiological assessment to minimise faecal contamination during investigations and procedures.\"},{\"question\":\"What prompted these consensus guidelines?\",\"answer\":\"A February 2009 Rapid Response Report from the UK National Patient Safety Agency highlighted potential harm associated with oral bowel-cleansing preparations and the need for safeguards.\"},{\"question\":\"What safeguards does the guidance emphasize for clinical assessment?\",\"answer\":\"It requires clinical assessment for contraindications and risks, clinician authorization, patient explanation on safe use, and a safe supply system for each patient.\"}]","Guidelines for the Safe Prescription and Administration of Oral Bowel-Cleansing Agents | PDF",1790556455]