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This five-wave clinical trial examines growth trajectories of psychological well-being—autonomy, environmental mastery, personal growth, positive relationships, and self-acceptance—comparing a preventive problem-solving intervention (PREPSI) with a social contact control condition. Mixed-model ANOVAs show declines across several outcomes over five waves and group differences in environmental mastery and self-acceptance, while purpose in life did not improve under PREPSI.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/growth-trajectories-in-psychological-well-being-a-clinical-trial-for-older-adults-with-macular-degeneration/428914/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/growth-trajectories-in-psychological-well-being-a-clinical-trial-for-older-adults-with-macular-degeneration/428914.png","ImageObject",300,407,{"name":92,"@type":93},"RuangKosong","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-05","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":29},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What psychological well-being dimensions were assessed in the study?","Question",{"text":112,"@type":113},"The study measured autonomy, environmental mastery, personal growth, positive relationships, and self-acceptance across five waves.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How did the treatment (PREPSI) differ from the control condition?",{"text":117,"@type":113},"Participants were randomized to PREPSI (preventive problem-solving intervention, n=90) or a social contact control condition using the Life and Health Review Intervention (LIHRI, n=90).",{"name":119,"@type":110,"acceptedAnswer":120},"Did PREPSI improve trajectories of purpose in life?",{"text":121,"@type":113},"No. Strong variation and a significant cubic change in purpose-in-life trajectories appeared for both groups, but PREPSI did not significantly enhance the purpose-in-life trajectory.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},428914,1790812705,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":29,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":8,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":81,"preview_page_count":4},962090883219,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","510 Innovation in Aging, 2025, Vol. 9, No. S2  \nAbstract citation ID: igaf122.1742  \nGROWTH TRAJECTORIES IN PSYCHOLOGICAL  \nWELL-BEING: A CLINICAL TRIAL FOR OLDER  \nADULTS WITH MACULAR DEGENERATION  \nPiaopiao Cai1, Timothy Powers1, and Silvia Sörensen2,  \n1. University of Rochester, Rochester, New York, United States,  \n2. University of Rochester Warner School of Education and Human Development, Rochester, New York, United States  \nAge-related macular degeneration (AMD) affects over 20% of aging populations (Lim et al., 2012) . AMD is a significant cause of visual impairment and severe vision loss (Mitchell et al., 2018), affecting around 37 million Americans aged 50 and above (Pelletier et al., 2016) . Our study aims to understand growth trajectories of psychological well-being (autonomy, environmental mastery, personal growth, positive relationships, and self-acceptance), utilizing a five-wave clinical trial study (Sörensen et al., 2015), that randomized participants into two groups:  \nTreatment (Preventive Problem-Solving Intervention (PREPSI, n = 90)); Social Contact Control (“Life and Health Review Intervention”(LIHRI, n = 90)) . Mixed-model ANOVAs showed a significant decline in perceptions of autonomy, environmental mastery, purpose in life, and self-acceptance after five waves (in both Intention to Treat (ITT) and Completed Case (CC) analysis), but stability in positive relationships with others and a marginally significant quadratic effect for personal growth in the CC analysis. Treatment and control groups differed significantly in trajectories of environmental mastery and self-acceptance; PREPSI respondents had significantly higher scores on these two outcomes after wave 4, while those in the control group exhibited a marked decrease. The minimum and maximum turning points of these trajectories were identical in CC analysis. Additionally, the strong variation and significant cubic change in the trajectories of purpose in life for both groups indicate that the PREPSI did not significantly enhance the purpose in life trajectory. The steady decline in wellbeing among people with vision loss and underlying individual and contextual influences require further investigation to guide future intervention development.","cbCaihQDsT94Pkkj","https://ap.wps.com/l/cbCaihQDsT94Pkkj","pdf",482975,"English","# Abstract\n## Study design and participants\n## Outcomes and statistical findings\n## Implications for future intervention development","[{\"question\":\"What psychological well-being dimensions were assessed in the study?\",\"answer\":\"The study measured autonomy, environmental mastery, personal growth, positive relationships, and self-acceptance across five waves.\"},{\"question\":\"How did the treatment (PREPSI) differ from the control condition?\",\"answer\":\"Participants were randomized to PREPSI (preventive problem-solving intervention, n=90) or a social contact control condition using the Life and Health Review Intervention (LIHRI, n=90).\"},{\"question\":\"Did PREPSI improve trajectories of purpose in life?\",\"answer\":\"No. Strong variation and a significant cubic change in purpose-in-life trajectories appeared for both groups, but PREPSI did not significantly enhance the purpose-in-life trajectory.\"}]","GROWTH TRAJECTORIES IN PSYCHOLOGICAL WELL-BEING: A CLINICAL TRIAL FOR OLDER ADULTS WITH MACULAR DEGENERATION | PDF",1790648099]