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Gold nanoparticles with impressive optical properties have become a leading platform in engineered cancer therapy. These theranostic systems support molecular detection, biological imaging, and cancer cell targeting. Gold nanorods’ photothermal behavior converts absorbed light into heat, enabling tumor cell destruction. This review summarizes optical features and advances for multiple cancers, including breast, lung, colon, oral, prostate, and pancreatic cancer.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/gold-nanoparticles-and-gold-nanorods-in-the-landscape-of-cancer-therapy/377971/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/gold-nanoparticles-and-gold-nanorods-in-the-landscape-of-cancer-therapy/377971.png","ImageObject",300,407,{"name":92,"@type":93},"Jake","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why are gold nanoparticles considered promising for cancer therapy?","Question",{"text":112,"@type":113},"Gold nanoparticles have impressive optical properties and enable a theranostic approach that supports detection, imaging, and targeting while minimizing adverse effects compared with some conventional options.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How do gold nanorods contribute to tumor cell destruction?",{"text":117,"@type":113},"Gold nanorods exhibit photothermal properties that convert absorbed incident light into heat, leading to tumor cell destruction.",{"name":119,"@type":110,"acceptedAnswer":120},"Which cancers are discussed in the review’s application focus?",{"text":121,"@type":113},"The review summarizes research for combating breast, lung, colon, oral, prostate, and pancreatic cancer.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},377971,1790807569,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145},962084928904,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Kesharwani etal. Molecular Cancer (2023) 22:98 [https://doi.org/10.1186/s12943-023-01798-8](https://doi.org/10.1186/s12943-023-01798-8)  \nMolecular Cancer  \n REVIEW Open Access  \nGold nanoparticles and gold nanorodsin the landscape of cancer therapy  \nPrashant Kesharwani1,2*†, Ruiyang Ma3†, Liang Sang4†, Mahak Fatima1†, Afsana Sheikh1†, Mohammed A. S. Abourehab5, Neelima Gupta6, Zhe‑Sheng Chen7 andYun Zhou8*  \nAbstract  \nCancer is a grievous disease whose treatment requires a more efficient, non‑invasive therapy, associated with minimal side effects. Gold nanoparticles possessing greatly impressive optical properties have been a forerunner in bioengi‑ neered cancer therapy. This theranostic system has gained immense popularity and finds its application in the field of molecular detection, biological imaging, cancer cell targeting, etc. The photothermal property of nanoparticles, especially of gold nanorods, causes absorption of the light incident by the light source, and transforms it into heat, resulting in tumor cell destruction. This review describes the different optical features of gold nanoparticles and sum‑ marizes the advance research done for the application of gold nanoparticles and precisely gold nanorods for combat‑ ing various cancers including breast, lung, colon, oral, prostate, and pancreatic cancer.  \nKeywords Gold nanoparticles, Gold nanorods, Cancer, Photothermal therapy, Chemotherapeutics, Reactive oxygen species  \n†Prashant Kesharwani, Ruiyang Ma, Liang Sang, Mahak Fatima and Afsana Sheikh contributed equally to the work.  \n*Correspondence: Prashant Kesharwani [prashantdops@gmail.com](prashantdops@gmail.com)[ ](prashantdops@gmail.com)Yun Zhou [zhouyuncmu@163.com](zhouyuncmu@163.com)  \n1 Department of Pharmaceutics, School of Pharmaceutical Education and Research, Jamia Hamdard, New Delhi 110062, India  \n2 Department of Pharmacology, Saveetha Dental College, Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India  \n3 Department of Otorhinolaryngology, The First Hospital of China Medical University, Shenyang, China  \n4 Department of Ultrasound, The First Hospital of China Medical University, Shenyang, China  \n5 Department of Pharmaceutics, College of Pharmacy, Umm Al‑Qura University, Makkah 21955, Saudi Arabia  \n6 Dr. Harisingh Gour Vishwavidyalaya (A Central University), Sagar, Madhya Pradesh 470003, India  \n7 Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John’s University, New York City, NY 11439, USA  \n8 Department of Ophthalmology, The First Hospital of China Medical University, Shenyang, China  \nIntroduction  \nCancer is the world’s second most prominent cause of mortality, trailing only cardiovascular disease [1–3]. Early diagnosis and treatment for cancer remain a technological roadblock at the moment. Despite major advancements in classic treatment options including radiation and chemotherapy cancer treatment remains far from ideal due to several drawbacks [2–7]. Prevailing cancer treatments frequently face challenges such as nonspecific systemic antitumor agent distribution, insufficient drug levels reaching the tumor site, unendurable cytotoxicity, restricted ability to monitor therapeutic outcomes, and the advancement of drug resistance [7–11]. Existing prognostic and diagnostic systems are inadequate to predict treatment efficacy and patient outcomes. Asa result, there is an urgent need and significant opportunity to develop new and innovative technologies that could aid in delineating tumor margins, identifying residual tumor cells and micrometastases, and determining whether a tumor has spread. Nanotechnology-enabled cancer testing and therapeutics have been created to  \n© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit t","cbCaily19lwGVbJW","https://ap.wps.com/l/cbCaily19lwGVbJW","pdf",2365746,31,"English","# Abstract\n# Keywords\n# Introduction\n# Cancer nanotechnology background\n# Licensing and open access notice","[{\"question\":\"Why are gold nanoparticles considered promising for cancer therapy?\",\"answer\":\"Gold nanoparticles have impressive optical properties and enable a theranostic approach that supports detection, imaging, and targeting while minimizing adverse effects compared with some conventional options.\"},{\"question\":\"How do gold nanorods contribute to tumor cell destruction?\",\"answer\":\"Gold nanorods exhibit photothermal properties that convert absorbed incident light into heat, leading to tumor cell destruction.\"},{\"question\":\"Which cancers are discussed in the review’s application focus?\",\"answer\":\"The review summarizes research for combating breast, lung, colon, oral, prostate, and pancreatic cancer.\"}]","Gold nanoparticles and gold nanorods in the landscape of cancer therapy | PDF",1790227853,78]