[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-detail-435952-en":59,"doc-seo-435952-105":79},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":5,"data":60},{"doc_id":61,"user_id":62,"nickname":63,"user_avatar":64,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":66,"doc_content":67,"file_id":68,"file_url":69,"file_type":70,"file_size":71,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":19,"language":72,"language_code":73,"site_id":74,"html_lang":73,"table_of_contents":75,"faqs":76,"seo_title":77,"seo_description":66,"update_tm":78,"read_time":52,"preview_page_count":4},435952,16904993612988,"Olivia Brown","https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Gilles de La Tourette syndrome: the contribution of Guinon","We review Georges Guinon’s contributions, a pupil of Jean-Martin Charcot, to the clinical description of Gilles de La Tourette syndrome. The review covers phenomenological definitions and the emergence of psychiatric findings, including obsessive-compulsive behavior, linked to tic disorders. It also contextualizes Guinon’s role relative to Charcot and Gilles de La Tourette, including how terminology and observations were refined.","Article published online: 2025-10-27  \nHistory of Neurology 1  \nGilles de La Tourette syndrome: the contribution of Guinon  \nHélio Afonso Ghizoni Teive 1,2 Francisco M. Branco Germiniani 1,2 Marcus Vinícius Della Coletta2,3 Carlos Henrique Ferreira Camargo2 Léo Coutinho2 Olivier Walusinski4  \n1 Universidade Federal do Paraná, Departamento de Clínica Médica, Serviço de Neurologia, Curitiba PR, Brazil.  \n2 Universidade Federal do Paraná, Programa de Pós-Graduação em Medicina Interna, Disciplina de Doenças Neurodegenerativas, Curitiba PR, Brazil.  \n3 Universidade Federal do Amazonas, Hospital Getúlio Vargas, Manaus AM, Brazil.  \n4 Private practice, Brou, France.  \nArq. Neuro-Psiquiatr. 2025;83(10):s00451812298 .  \nAddress for correspondence Léo Coutinho (email: [leocoutinho23@hotmail.com](leocoutinho23@hotmail.com))  \nAbstract  \nKeywords  \n► Neurology  \n► Movement Disorders  \n► Tics  \n► Tourette Syndrome  \n► History  \n► 19th Century  \nWe review the contributions of Georges Guinon, an eminent pupil of Professor JeanMartin Charcot, to the clinical description of Gilles de La Tourette syndrome, including phenomenological definitions and the occurrence of psychiatric findings such as obsessive-compulsive behavior.  \nINTRODUCTION  \nProfessor Jean-Martin Charcot’s (1825–1893) contribution to the description of various neurological diseases is widely known.1–3 In the field of movement disorders, particularly the study of tics and the definition of Gilles de La Tourette’s syndrome (GTS), Charcot and his pupils presented invaluable contributions.2,4–7 Although the works of Charcot and Gilles de La Tourette for the description of the syndrome are well known, one of Charcot’s pupils, Georges Guinon (1859-1932), also presented an instrumental contribution to the understanding of tic disorders.  \nThe present study reviews the contributions of Georges Guinon in describing the syndrome now defined as GTS.  \nGEORGES GILLES DE LA TOURETTE (1857–1904)  \nGeorge Gilles de La Tourette was born on October 30, 1857, in Saint-Gervais-les-Trois-Clochers, France. He died on May 22, 1904, in Lausanne, Switzerland.4–10 Gilles de La Tourette started his activities as a clinician at the Salpêtrière Hospital, in 1884. He was later promoted to the post of Charcot’s registrar, and finally to Chief de Clinique, in 1887 to 1888.5–7,9,10 Gilles de La Tourette’s academic career will always be remembered for his publications in the area of hysteria and hypnotism, as well as forensic medicine and movement disorders. 5–7,9–11 Nevertheless, his most important work was the first description in 1885 of a new disorder which Charcot would later name GTS. 5–7,9–15 While Gilles de  \nreceived  \nApril 20, 2025  \nreceived in its final form August 1, 2025  \naccepted  \nAugust 24, 2025  \nDOI [https://doi.org/](https://doi.org/)[ ](https://doi.org/)10.1055/s-0045-1812298 . ISSN 0004-282X.  \nEditor-in-Chief: Ayrton Roberto Massaro.  \nAssociate Editor: Ethel Mizrahy Cuperschmid.  \n© 2025 . The Author(s) .  \nThis is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit ([https://creativecommons.org/licenses/by/4.0/](https://creativecommons.org/licenses/by/4.0/))  \nThieme Revinter Publicações Ltda. , Rua Rego Freitas, 175, loja 1, República, São Paulo, SP, CEP 01220-010, Brazil  \n2 Charcot, Tourette, Guinon and the tics Teive et al.  \nTable 1 Contributions of Charcot, Gilles de La Tourette, and Guinon in the clinical definition of Gilles de La Tourette ’s syndrome (GTS)  \n\n| Contribution/Author | Jean-Martin Charcot | Georges Gilles\u003Cbr>de La Tourette | Georges\u003Cbr>Guinon |\n| --- | --- | --- | --- |\n| The original idea for research | þ | - | - |\n| The first publication of GTS | 􀀂 | þ | 􀀂 |\n| Criticism to the title of GTS paper- “incoordenation motrice” | þ | 􀀂 | þ |\n| Obsessive-Compulsive Disorder: “idées fixes”: | þ | 􀀂 | 􀀂 |\n| “Folie du po","cbCaih6ggAIXFsoO","https://ap.wps.com/l/cbCaih6ggAIXFsoO","pdf",920378,"English","en",105,"# Introduction\n# Georges Gilles de La Tourette (1857–1904)\n# Georges Guinon (1859–1932)\n# Defining Gilles de La Tourette syndrome: the contribution of Guinon","[{\"question\":\"What contributions of Georges Guinon are reviewed in the article?\",\"answer\":\"The article reviews Guinon’s contributions to the clinical description of Gilles de La Tourette syndrome, including phenomenological definitions and related psychiatric findings such as obsessive-compulsive behavior.\"},{\"question\":\"How does the article relate Guinon’s work to Charcot and Gilles de La Tourette?\",\"answer\":\"It positions Guinon as a Charcot pupil and later as a clinician associated with Charcot’s work, describing how his observations and refinements complemented or differed from earlier descriptions by Charcot and Gilles de La Tourette.\"},{\"question\":\"What key focus does the article give to psychiatric findings in Tourette syndrome?\",\"answer\":\"It highlights psychiatric features, particularly obsessive-compulsive behavior, as part of the syndrome’s clinical characterization as influenced by Guinon’s work.\"}]","Gilles de La Tourette syndrome: the contribution of Guinon | 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