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Questions cover coronary heart disease, including affected blood vessels, cardiopulmonary resuscitation actions, drug therapy to lower cholesterol, and how stents restore heart function. Students also interpret data on smoking risks for cardiovascular disease, complete a chart, and discuss lifestyle factors. Later questions address cystic fibrosis, gene location in cells, organ effects, digestion, and alveoli adaptations for gas exchange.",{"@graph":69,"@context":116},[70,84,99],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":20,"@type":76,"position":81},"https://docshare.wps.com/document/exam/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/gcse-biology-higher-tier-paper-1-h-friday-10-may-2024/207407/",{"url":83,"name":65,"@type":85,"author":86,"headline":65,"publisher":89,"fileFormat":92,"inLanguage":63,"description":67,"dateModified":93,"datePublished":93,"encodingFormat":92,"isAccessibleForFree":94,"interactionStatistic":95},"DigitalDocument",{"name":87,"@type":88},"Theodore","Person",{"url":74,"name":90,"@type":91},"DocShare","Organization","application/pdf","2026-09-05",true,{"@type":96,"interactionType":97,"userInteractionCount":4},"InteractionCounter",{"@type":98},"ViewAction",{"@type":100,"mainEntity":101},"FAQPage",[102,108,112],{"name":103,"@type":104,"acceptedAnswer":105},"Which blood vessels are affected by coronary heart disease?","Question",{"text":106,"@type":107},"Coronary heart disease affects the arteries.","Answer",{"name":109,"@type":104,"acceptedAnswer":110},"How does forcing air into the lungs help a person during resuscitation?",{"text":111,"@type":107},"Forcing air into the lungs increases air reaching the alveoli, allowing gas exchange to support breathing and oxygenation.",{"name":113,"@type":104,"acceptedAnswer":114},"Where is the cystic fibrosis (CF) gene found in a cell?",{"text":115,"@type":107},"The CF gene is found on chromosomes in the cell nucleus.","https://schema.org",{"og:url":83,"og:type":118,"og:title":65,"og:site_name":90,"og:description":67},"article",{"robots":120,"canonical":83},"index,follow",{"doc_id":122,"site_id":62},207407,1788599467,{"code":4,"msg":5,"data":125},{"doc_id":122,"user_id":126,"nickname":87,"user_avatar":127,"doc_module":4,"category_id":19,"category_name":20,"doc_title":65,"doc_description":67,"doc_content":128,"file_id":129,"file_url":130,"file_type":131,"file_size":132,"view_count":4,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":133,"language":134,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":135,"faqs":136,"seo_title":137,"seo_description":67,"update_tm":123,"read_time":138},7971461740886,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","| Please write clearly in block capitals. |  |  |  |\n| --- | --- | --- | --- |\n| Centre number |  | Candidate number |  |\n| Surname  \u003Cbr>Forename(s)  \u003Cbr>Candidate signature  \u003Cbr>I declare this is my own work. |  |  |  |\n\nGCSE  \nBIOLOGY  \nHigher Tier Paper 1 H  \nH  \nFriday 10 May 2024 Morning Time allowed: 1 hour 45 minutes  \nMaterials  \nFor this paper you must have:  \n• a ruler  \n• a scientific calculator.  \nInstructions  \n• Use black ink or black ball-point pen.  \n• Pencil should only be used for drawing.  \n• Fill in the boxes at the top of this page.  \n• Answer all questions in the spaces provided.  \n• If you need extra space for your answer(s), use the lined pages at the end of this book. Write the question number against your answer(s) .  \n• Do all rough work in this book. Cross through any work you do not want to be marked.  \n• In all calculations, show clearly how you work out your answer.  \nInformation  \n• The maximum mark for this paper is 100.  \n• The marks for questions are shown in brackets.  \n• You are expected to use a calculator where appropriate.  \n• You are reminded of the need for good English and clear presentation in your answers.  \n\n| For Examiner’s Use |  |\n| --- | --- |\n| Question | Mark |\n| 1 |  |\n| 2 |  |\n| 3 |  |\n| 4 |  |\n| 5 |  |\n| 6 |  |\n| 7 |  |\n| 8 |  |\n| TOTAL |  |\n\n\n| Answer all questions in the spaces provided. |  |  |\n| --- | --- | --- |\n| \u003Cbr> 0  1  A person has coronary heart disease.\u003Cbr> 0  1  .  1 Which blood vessels are affected by coronary heart disease? |  |  |\n| Tick ( 􀀹 ) one box.\u003Cbr>Arteries\u003Cbr>Capillaries\u003Cbr>Veins | | [1 mark] |\n| A person’s heart stops beating.\u003Cbr>The person stops breathing.\u003Cbr>A first-aider pushes down on the person’s chest.\u003Cbr>Pushing down on the person’s chest puts pressure on the heart.\u003Cbr>\u003Cbr> 0  1  .  2  Explain why putting pressure on the heart helps the person.\u003Cbr>[2 marks]\u003Cbr> |  |  |\n\noutside the box  \n 0  1  .  3 The first-aider also forces air into the person’s lungs by blowing into their mouth.  \nDescribe how forcing air into the person’s lungs helps the person.  \n[1 mark]  \n 0  1  .  4 The person’s heart starts to beat again and the person starts breathing.  \nThe person has a high level of cholesterol in their blood.  \nName one type of drug that would decrease the level of cholesterol in the person’s blood.  \n[1 mark]  \n 0  1  .  5 A doctor decides that the person needs to have a stent fitted.  \nExplain how a stent works to treat coronary heart disease.  \n[2 marks]  \n\n|  |\n| --- |\n|  |\n|  |\n\nQuestion 1 continues on the next page  \noutside the box  \nTable 1 shows the effect of smoking on the risk of developing different cardiovascular diseases.  \nTable 1  \n\n| Cardiovascular disease | Percentage (%) increase in risk compared to people who have never smoked |\n| --- | --- |\n| E | 14 |\n| F | 20 |\n| G | 29 |\n| H | 70 |\n\n 0  1  .  6 Give two conclusions that can be made from the data in Table 1.  \n[2 marks]  \n1    \n2  \n0  1  .  7  Complete Figure 1.  \nYou should:  \n• label the y-axis  \n• add the correct scale to the y-axis  \n• plot the data from Table 1  \n• label each bar.  \nThe bar for cardiovascular disease E has been plotted for you.  \n[4 marks]  \noutside the box  \nFigure 1  \n0  1  .  8 Describe one lifestyle factor that can increase the risk of cardiovascular disease.  \nDo not refer to smoking in your answer.  \n[1 mark]  \nbox  \n\n|  |\n| --- |\n| 14 |\n\n0  2 Cystic fibrosis (CF) is an inherited disorder caused by a faulty gene.  \n 0  2  .  1 Where in a cell would the CF gene be found?  \n[1 mark]  \noutside the box  \nCF affects many organs in the body.  \nThe main organs affected are:  \n• the lungs  \n• the pancreas  \n• the small intestine.  \n 0  2  .  2 Figure 2 shows organs of the human body.  \nFigure 2  \nWhich letters in Figure 2 show the lungs, the pancreas and the small intestine?  \n[1 mark]  \nTick ( 􀀹 ) one box.  \nA, D and E   \nA, E and F B, C and D   \nB, C and F   \nQuestion 2 continues on the next page  \noutside the box  \n0  2  .  3  The pancreas produces","cbCainikuZ1aizHq","https://ap.wps.com/l/cbCainikuZ1aizHq","pdf",503345,36,"English","# Instructions\n## Materials\n## Instructions for answering\n# Question 1: Cardiovascular disease\n## Coronary heart disease and circulation\n## First aid and resuscitation pressure\n## Drugs and stent treatment\n## Smoking risk data (Table 1) and conclusions\n## Figure 1 plotting and labelling\n## Lifestyle factor question (no smoking)\n# Question 2: Cystic fibrosis (CF)\n## Faulty gene location and affected organs (Figure 2)\n## Digestion and gaining body mass\n## Alveoli features for gas exchange\n## Effects of reduced oxygen entering the blood","[{\"question\":\"Which blood vessels are affected by coronary heart disease?\",\"answer\":\"Coronary heart disease affects the arteries.\"},{\"question\":\"How does forcing air into the lungs help a person during resuscitation?\",\"answer\":\"Forcing air into the lungs increases air reaching the alveoli, allowing gas exchange to support breathing and oxygenation.\"},{\"question\":\"Where is the cystic fibrosis (CF) gene found in a cell?\",\"answer\":\"The CF gene is found on chromosomes in the cell nucleus.\"}]","GCSE Biology Higher Tier Paper 1 H - Friday 10 May 2024 | PDF",91]