[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-433196-105":59,"doc-detail-433196-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","gastrointestinal-mucormycosis-in-the-setting-of-colonic-pseudo-obstruction","Gastrointestinal Mucormycosis in the Setting of Colonic Pseudo-Obstruction","","A 49-year-old man with poorly controlled diabetes and hypertension developed acute-on-chronic abdominal pain that rapidly worsened over 24 hours. He had chronic intestinal pseudo-obstruction with pneumatosis of the transverse colonic wall requiring total abdominal colectomy. Within two weeks, he developed fundal gastric injury with herniation requiring laparotomy. Histopathology showed broad irregular fungal hyphae identified as Rhizopus microsporus by broad-spectrum PCR. Gastrointestinal mucormycosis is an emerging, high-mortality invasive fungal disease often diagnosed after death, with diabetes and other comorbidities as key risks.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/gastrointestinal-mucormycosis-in-the-setting-of-colonic-pseudo-obstruction/433196/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/gastrointestinal-mucormycosis-in-the-setting-of-colonic-pseudo-obstruction/433196.png","ImageObject",300,407,{"name":92,"@type":93},"jayni","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What organism was identified in the patient’s tissue pathology?","Question",{"text":113,"@type":114},"Histopathology revealed broad irregular fungal hyphae, which were identified as Rhizopus microsporus by broad-spectrum PCR.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What underlying condition did the patient have before surgery?",{"text":118,"@type":114},"He had chronic intestinal pseudo-obstruction with pneumatosis of the transverse colonic wall requiring total abdominal colectomy.",{"name":120,"@type":111,"acceptedAnswer":121},"What risk factors are highlighted for gastrointestinal mucormycosis?",{"text":122,"@type":114},"The article notes risk factors such as chronic diseases including diabetes and malignancy, communicable diseases like COVID-19, and other immunocompromising conditions.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},433196,1790764093,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":39,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":46,"preview_page_count":4},3985747859343,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","Review began 10/03/2025  \nReview ended 11/23/2025  \nPublished 12/03/2025  \n© Copyright 2025  \nDomenici et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CCBY 4.0. , which permits unrestricted use , distribution , and reproduction in any medium , provided the original author and source are credited.  \nDOI: 10.7759/cureus.98414  \nOpen Access Case Report  \nGastrointestinal Mucormycosis in the Setting of Colonic Pseudo-Obstruction  \nKatherine Domenici 1, Matthew Cappiello 1  \n1. Infectious Diseases, Loma Linda University Medical Center, Loma Linda, USA Corresponding author: Matthew Cappiello, [mcappiello@llu.edu](mcappiello@llu.edu)  \nAbstract  \nMucormycosis is a rare opportunistic infection caused by the fungi order Mucorales that can affect multiple different organ systems. A 49-year-old man with a history of poorly controlled diabetes and hypertension presented with acute-on-chronic abdominal pain with profound worsening in the past 24 hours. He was found to have chronic intestinal pseudo-obstruction, with pneumatosis of the transverse colonic wall requiring total abdominal colectomy. Within two weeks after surgery, he developed fundal gastric injury with herniation requiring primary repair with surgical laparotomy. Tissue histopathology post-procedure revealed broad and irregular fungal hyphae, revealed to be Rhizopus microsporus on broad-spectrum PCR. Gastrointestinal mucormycosis is an emerging invasive fungal disease, often diagnosed post-mortem due to high mortality rates. Risk factors include noncommunicable chronic diseases such as diabetes and malignancy, as well as communicable diseases, including COVID-19 . Surgical debridement is key to improving outcomes, as infection tends to cross tissue planes without adequate source control.  \nCategories: Cardiac/Thoracic/Vascular Surgery, Infectious Disease, Gastroenterology  \nKeywords: colonic pseudo-obstruction, covid-associated mucor mycosis, gastrointestinal mucormycosis, invasive fungal disease, mucor, rhizopus, traumatic diaphragm injury repair, tropical medicine  \nIntroduction  \nMucormycosis is a spectrum of invasive fungal diseases caused by the genera of the order Mucorales [1] . Currently defined within the phylum Mucoromycota and historically defined within the phylum Zygomycota, the spectrum of mucormycosis currently includes 261 species and 55 genera, with over 30 species causing disease in humans [2] . Gastrointestinal mucormycosis is one of the most uncommon presentations ofthe disease, occurring in the context of infectious events, such as abdominal wall soft-tissue infection, or surgical events, such as upper or lower gastrointestinal perforation [3] . Gastrointestinal mucormycosis accounts for approximately 2-8% of all cases [4] . Although the condition is frequently life-threatening in both immunocompetent and immunocompromised patients, diagnosis can occur unexpectedly, often while in the setting of hospitalization for an alternate or secondary reason [5] . Risk factors include chronic comorbidities such as diabetes, renal failure, and primary and secondary immunodeficiencies, as well as acute events such as abdominal trauma or gastrointestinal perforation [3] . In addition, health-associated gastrointestinal mucormycosis has been associated with prolonged intensive care hospitalization [6] .  \nCase Presentation  \nA 49-year-old man with a history of poorly controlled diabetes and hypertension presented with acute-onchronic abdominal pain and distention for 24 hours. Review of systems included multiple episodes of nausea and non-bloody nonbilious vomiting, as well as constipation with his last bowel movement four days prior to admission. The patient denied any fevers, chills, or active cough. The patient additionally denied any diarrhoea, hematochezia, or melena. He denied any sick contacts or recent travel, with two domesticated dogs as pets.  \nOn past medical history, the patient was recently diagn","cbCaimLukw32wUXF","https://ap.wps.com/l/cbCaimLukw32wUXF","pdf",3432757,"English","# Abstract\n# Introduction\n# Case Presentation\n# How to cite this article","[{\"question\":\"What organism was identified in the patient’s tissue pathology?\",\"answer\":\"Histopathology revealed broad irregular fungal hyphae, which were identified as Rhizopus microsporus by broad-spectrum PCR.\"},{\"question\":\"What underlying condition did the patient have before surgery?\",\"answer\":\"He had chronic intestinal pseudo-obstruction with pneumatosis of the transverse colonic wall requiring total abdominal colectomy.\"},{\"question\":\"What risk factors are highlighted for gastrointestinal mucormycosis?\",\"answer\":\"The article notes risk factors such as chronic diseases including diabetes and malignancy, communicable diseases like COVID-19, and other immunocompromising conditions.\"}]","Gastrointestinal Mucormycosis in the Setting of Colonic Pseudo-Obstruction | PDF",1790663140]