[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-detail-371113-en":59,"doc-seo-371113-105":81},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":5,"data":60},{"doc_id":61,"user_id":62,"nickname":63,"user_avatar":64,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":66,"doc_content":67,"file_id":68,"file_url":69,"file_type":70,"file_size":71,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":72,"language":73,"language_code":74,"site_id":75,"html_lang":74,"table_of_contents":76,"faqs":77,"seo_title":78,"seo_description":66,"update_tm":79,"read_time":80},371113,3985747870733,"acoobca","https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Function-preserving surgery in gastric cancer - current evidence and implications for the West","Gastric cancer remains a major global health challenge, and standard gastrectomy can impair nutritional status and quality of life. Function-preserving surgical approaches, more widely adopted in East Asia for early detection, show promise in improving postoperative outcomes. This review explains how pylorus-preserving and proximal gastrectomy aim to maintain gastric function with oncological safety, summarizes additional function-sparing options under investigation, and analyzes reconstruction-related complications.","Santocchi etal. World Journal of Surgical Oncology (2026) 24:62  \n[https://doi.org/10.1186/s12957-025-04173-7](https://doi.org/10.1186/s12957-025-04173-7)  \nWorld Journal of Surgical Oncology  \nREVIEW Open Access  \nFunction-preserving surgery in gastric cancer: current evidence and implications for the West  \nPietro Santocchi 1, Annamaria Agnes2,3* and Alberto Biondi2,3  \nAbstract  \nBackground Gastric cancer remains a significant global health challenge. Surgical resection continues to be the cornerstone of treatment, but traditional gastrectomy is often associated with negative impacts on nutritional status and quality of life. Function-preserving surgical techniques, widely adopted in East Asian countries due to early cancer detection, have shown promise in improving postoperative outcomes. In contrast, Western guidelines have yet to integrate these procedures into routine practice.  \nMain body Function-preserving surgeries, including pylorus-preserving gastrectomy and proximal gastrectomy, aim to maintain gastric function while ensuring oncological safety. These procedures are primarily indicated for early gastric cancers and have demonstrated comparable survival outcomes to standard resections in well-selected patients. Endoscopic resections and segmental gastrectomy represent additional function-sparing options under investigation. The main functional complications, such as gastric stasis or reflux esophagitis, have prompted the development of various reconstructive techniques, including double-tract methods, jejunal interposition, and pouch reconstructions. Despite their proven benefits in Eastern countries, the implementation of these surgeries in Western settings is limited. Challenges include the lower incidence of early gastric cancer, lack of surgeon experience, and absence of guideline endorsement. However, increased centralization of care, enhanced diagnostic accuracy, and growing emphasis on patient-reported outcomes have reignited interest in adapting these strategies for Western populations. Additionally, emerging evidence suggests that even patients with more advanced disease may benefit from improved short-term functional outcomes, potentially aiding in faster recovery and return to adjuvant therapies. Conclusion Function-preserving surgery in gastric cancer offers oncologically safe alternatives that may significantly improve postoperative quality of life and nutritional outcomes. As global treatment paradigms evolve, adapting these techniques in the West, particularly within high-volume centers, could represent a significant step forward. Further randomized trials and Western-centric data are essential to validate the broader applicability of these procedures andrefine patient selection criteria.  \n*Correspondence:  \nAnnamaria Agnes  \n[annamaria.agnes@policlinicogemel li.it](annamaria.agnes@policlinicogemel li.it)  \n1Oncologic and Emergency Surgery Unit, Policlinico Casil ino, Via Casilina 1049, Rome 00169, Italy  \n2General Surgery Unit, Department of Medical and Surgical Sciences, Fondazione Policlinico Universitario Agostino Gemell i IRCCS, Largo A. Gemelli n. 8, Rome 00168, Italy  \n3Università Cattolica del Sacro Cuore, Largo F. Vito n. 1, Rome 00168, Italy  \n© The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the ar","cbCaiuCBS2kNOnpO","https://ap.wps.com/l/cbCaiuCBS2kNOnpO","pdf",1842238,14,"English","en",105,"# Abstract\n# Introduction\n## Global burden and epidemiology of gastric cancer\n## Rationale for function-preserving surgery\n# Main body\n## Surgical techniques and indications\n## Oncological safety and survival outcomes\n## Endoscopic and segmental options under investigation\n## Functional complications and reconstruction methods\n## Barriers to adoption in Western practice\n## Opportunities and emerging evidence","[{\"question\":\"What is the main goal of function-preserving surgery in gastric cancer?\",\"answer\":\"It aims to maintain gastric function while preserving oncological safety after resection, reducing negative effects on nutrition and quality of life.\"},{\"question\":\"Which function-preserving procedures are discussed?\",\"answer\":\"The review focuses on pylorus-preserving gastrectomy and proximal gastrectomy, and also mentions additional function-sparing options such as endoscopic resections and segmental gastrectomy under investigation.\"},{\"question\":\"Why is implementation limited in Western countries?\",\"answer\":\"The article highlights a lower incidence of early gastric cancer, limited surgeon experience, and the lack of guideline endorsement in routine Western practice.\"}]","Function-preserving surgery in gastric cancer - current evidence and implications for the West | PDF",1790191276,35,{"code":4,"msg":82,"data":83},"ok",{"site_id":75,"language":74,"slug":84,"title":65,"keywords":85,"description":66,"schema_data":86,"social_meta":140,"head_meta":142,"extra_data":144,"updated_unix":145},"function-preserving-surgery-in-gastric-cancer-current-evidence-and-implications-for-the-west","",{"@graph":87,"@context":139},[88,102,122],{"@type":89,"itemListElement":90},"BreadcrumbList",[91,95,97,100],{"item":92,"name":93,"@type":94,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":96,"name":9,"@type":94,"position":14},"https://docshare.wps.com/document/",{"item":98,"name":35,"@type":94,"position":99},"https://docshare.wps.com/document/healthcare/",3,{"item":101,"name":65,"@type":94,"position":19},"https://docshare.wps.com/document/function-preserving-surgery-in-gastric-cancer-current-evidence-and-implications-for-the-west/371113/",{"url":101,"name":65,"@type":103,"image":104,"author":109,"headline":65,"publisher":111,"fileFormat":114,"inLanguage":74,"description":66,"dateModified":115,"datePublished":116,"encodingFormat":114,"isAccessibleForFree":117,"interactionStatistic":118},"DigitalDocument",{"url":105,"@type":106,"width":107,"height":108},"https://docshare.wps.com/thumbnails/function-preserving-surgery-in-gastric-cancer-current-evidence-and-implications-for-the-west/371113.png","ImageObject",300,407,{"name":63,"@type":110},"Person",{"url":92,"name":112,"@type":113},"DocShare","Organization","application/pdf","2026-10-29","2026-09-23",true,{"@type":119,"interactionType":120,"userInteractionCount":52},"InteractionCounter",{"@type":121},"ViewAction",{"@type":123,"mainEntity":124},"FAQPage",[125,131,135],{"name":126,"@type":127,"acceptedAnswer":128},"What is the main goal of function-preserving surgery in gastric cancer?","Question",{"text":129,"@type":130},"It aims to maintain gastric function while preserving oncological safety after resection, reducing negative effects on nutrition and quality of life.","Answer",{"name":132,"@type":127,"acceptedAnswer":133},"Which function-preserving procedures are discussed?",{"text":134,"@type":130},"The review focuses on pylorus-preserving gastrectomy and proximal gastrectomy, and also mentions additional function-sparing options such as endoscopic resections and segmental gastrectomy under investigation.",{"name":136,"@type":127,"acceptedAnswer":137},"Why is implementation limited in Western countries?",{"text":138,"@type":130},"The article highlights a lower incidence of early gastric cancer, limited surgeon experience, and the lack of guideline endorsement in routine Western practice.","https://schema.org",{"og:url":101,"og:type":141,"og:title":65,"og:site_name":112,"og:description":66},"article",{"robots":143,"canonical":101},"index,follow",{"doc_id":61,"site_id":75},1790473467]