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The perspective argues that AMR is shaped by social, behavioural, technological, and cultural drivers, and highlights a parallel crisis in the AMR research workforce, including shrinking expertise due to brain drain and limited career progression. It emphasizes early-career researchers (ECRs) and presents strategies to sustain transdisciplinary innovation through equitable support, recognition, and cross-sector collaboration.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/from-the-lens-of-early-career-researchers-bridging-science-technology-arts-and-humanities-to-tackle-antimicrobial-resistance/455653/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/from-the-lens-of-early-career-researchers-bridging-science-technology-arts-and-humanities-to-tackle-antimicrobial-resistance/455653.png","ImageObject",300,407,{"name":92,"@type":93},"Miles","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-05","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":19},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why does the article say AMR requires cross-disciplinary solutions?","Question",{"text":112,"@type":113},"AMR is described as a medical challenge that is also driven by societal factors, so solutions must address social, behavioural, technological, and cultural dimensions beyond laboratory-based discovery.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What workforce issue does the perspective highlight in AMR research?",{"text":117,"@type":113},"It points to a parallel crisis in the AMR research workforce, noting declining numbers of professionals and a brain drain driven by funding uncertainty and limited career progression opportunities.",{"name":119,"@type":110,"acceptedAnswer":120},"How does the perspective define early-career researchers (ECRs)?",{"text":121,"@type":113},"ECRs are defined as researchers in the first independent stages of their careers, typically within eight years of a PhD award or six years of a first academic appointment; biomedical contexts include early stage investigators within ten years of terminal degree or clinical training.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},455653,1790967444,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":19,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":39,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":46},13056703019404,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","Perspective [https://doi.org/10.1038/s41467-025-67863-6](https://doi.org/10.1038/s41467-025-67863-6)  \nFrom the lens of early-career researchers: bridging science, technology, arts, and humanities to tackle antimicrobial resistance  \n\n| Received: 18 June 2025\u003Cbr>Accepted: 10 December 2025\u003Cbr>| Nikhil Bhalla 1 , Mojgan Rabiey2, Prachi Bendale3, Katie Lawther3, Janice Spencer4, Alberto Longo3, Lucky Lucky5, Vishal Chaudhary 6, Paul McCormack7, Saikat Jana1, Patrick S. M. Dunlop 1 & Linda Oyama 3  |  |\n| --- | --- | --- |\n| | Antimicrobial resistance (AMR) is a silent pandemic that presents a global challenge, urging researchers to develop innovative and transdisciplinary solutions. Our initiative aims to promote collaboration across science, engineering, economics, social sciences, and the arts to address the complex dimensions ofAMR. We highlight the unique role of early-career researchers (ECRs) in advancing such cross-cutting approaches and conclude that empowering ECRs through equitable support and recognition is essential to sustaining innovation and mobilising communities against AMR. |  |\n| Antimicrobial resistance (AMR) is a silent pandemic that threatens health systems, economies, and societies globally1. While AMR is fundamentally a medical challenge because it undermines treatment effectiveness, it is simultaneously driven by societal factors and therefore requires cross-disciplinary solutions2. Recent analyses have also highlighted a parallel crisis in the AMR research workforce, with declining numbers of professionals engaged in antimicrobial research and development (’brain drain’), driven by funding uncertainty and limited career progression opportunities3,4. This contraction of expertise indicates the urgency of sustaining and diversifying the talent pipeline, particularly through strengthened support for Early Career Researchers (ECRs) who represent the next generation of innovation and leadership in this field. Solutions must therefore extend beyond laboratory-based discovery to encompass social, behavioural, technological, and cultural dimensions. Addressing AMR requires more than collaboration within traditional scientific boundaries as it depends on bridging sectors from laboratory research and clinical practice to social science, arts, and policy engagement. Social science studies have demonstrated how prescribing practices, patient expectations, and community norms influence antibiotic use. Integrating these insights with biomedical and technological advances is |  | essential for designing interventions that are context-sensitive, equitable, and sustainable5,6.\u003Cbr>ECRs, here defined as researchers in the first independent stages of their careers, typically within eight years of PhD award or six years of first academic appointment7, or, in biomedical contexts, early stage investigators within ten years of terminal degree or clinical training and without a prior substantial independent award8, are not only contributing to this landscape, they are reshaping it. As the generation of scientists who will inherit the long-term consequencesofAMR, ECRsare also uniquely positioned and personally invested in driving sustainable, transdisciplinary solutions. This perspective highlights how ECRs are redefining AMR research by bridging Science, Technology, Engineering, and Mathematics (STEM), social sciences and humanities, and proposes strategies to empower the next generation to sustain this momentum.\u003Cbr>AMR is like a complex puzzle, with each piece representing a different aspect of society, culture, and human behaviour. To solve this puzzle, it is necessary to bridge together diverse perspectives and skills in a single cohort. Furthermore, the crux of the AMR crisis is the relationship between humans and microorganisms9. A diverse coalition of researchers, healthcare professionals, engineers, and policymakers are on the frontline creating new antibiotics, diagnostic tools, |\n\n1Nanotechnology and Integrated Bioengineering ","cbCaibA5D3D7oYeB","https://ap.wps.com/l/cbCaibA5D3D7oYeB","pdf",1452231,"English","# Introduction\n# Interdisciplinary need for AMR solutions\n# Defining early-career researchers (ECRs)\n# Bridging STEM with social sciences and humanities\n# Implications for policy and interventions","[{\"question\":\"Why does the article say AMR requires cross-disciplinary solutions?\",\"answer\":\"AMR is described as a medical challenge that is also driven by societal factors, so solutions must address social, behavioural, technological, and cultural dimensions beyond laboratory-based discovery.\"},{\"question\":\"What workforce issue does the perspective highlight in AMR research?\",\"answer\":\"It points to a parallel crisis in the AMR research workforce, noting declining numbers of professionals and a brain drain driven by funding uncertainty and limited career progression opportunities.\"},{\"question\":\"How does the perspective define early-career researchers (ECRs)?\",\"answer\":\"ECRs are defined as researchers in the first independent stages of their careers, typically within eight years of a PhD award or six years of a first academic appointment; biomedical contexts include early stage investigators within ten years of terminal degree or clinical training.\"}]","From the lens of early-career researchers - bridging science, technology, arts, and humanities to tackle antimicrobial resistance | PDF",1790743767]