[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-448047-105":59,"doc-detail-448047-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","forced-oscillometry-technique-in-the-assessment-of-adults-with-cystic-fibrosis-treated-for-a-pulmonary-exacerbation-a-pilot-feasibility-study","Forced oscillometry technique in the assessment of adults with cystic fibrosis treated for a pulmonary exacerbation - a pilot feasibility study","","Effective management of pulmonary exacerbations in cystic fibrosis is essential to limit lung damage and reduce morbidity and mortality. Spirometry, the standard adult lung-function assessment tool, has limitations, particularly for detecting early small airways changes. This pilot feasibility study evaluated implementation, patient acceptability, and initial performance of forced oscillometry during treatment for pulmonary exacerbation in adults with cystic fibrosis.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/forced-oscillometry-technique-in-the-assessment-of-adults-with-cystic-fibrosis-treated-for-a-pulmonary-exacerbation-a-pilot-feasibility-study/448047/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/forced-oscillometry-technique-in-the-assessment-of-adults-with-cystic-fibrosis-treated-for-a-pulmonary-exacerbation-a-pilot-feasibility-study/448047.png","ImageObject",300,407,{"name":92,"@type":93},"Hazel","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-07","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",14,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why is forced oscillometry technique (FOT) considered for monitoring pulmonary exacerbations in adults with cystic fibrosis?","Question",{"text":113,"@type":114},"Spirometry is limited in sensitivity for small airways changes, and forced expiratory manoeuvres can be unpopular when patients are unwell. FOT is effort-independent and targets small airway disease.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What did the study assess during pulmonary exacerbation treatment?",{"text":118,"@type":114},"It assessed feasibility and acceptability by measuring FOT and spirometry at PEx onset and end, plus at convenient intervals, and by measuring FOT before and after physiotherapy-directed airway clearance.",{"name":120,"@type":111,"acceptedAnswer":121},"What were the key findings regarding lung function and patient preferences?",{"text":122,"@type":114},"FOT showed small airways dysfunction at PEx onset, treatment was associated with improvements in FEV1pp and X5, and there was no significant FOT change after airway clearance. Patients rated FOT more favourably than spirometry.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},448047,1790794154,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},137441390410,"https://ap-avatar.wpscdn.com/avatar/2000252f4ab5702993?_k=1776741390130283984","Forced oscillometry technique in the assessment of adults with cystic fi brosis treated for a pulmonary exacerbation, a pilot feasibility study  \nChronic Respiratory Disease Volume 23: 1–9 © The Author(s) 2026 Article reuse guidelines:  \n[sagepub.com/journals-permissions](sagepub.com/journals-permissions)[ ](sagepub.com/journals-permissions)[DOI: 10.1177/14799731251414105](DOI: 10.1177/14799731251414105)  \n[journals.sagepub.com/home/crd](journals.sagepub.com/home/crd)  \nJames Nolan 1,2 􀀁, Jennifer Bingham3, Robyn Cobb3, Kathleen Hall3,4, Pei Onn 1, Karen Hay5, Michelle Wood 1 and David W. Reid 1,2,5  \nAbstract  \nIntroduction: Effective management of pulmonary exacerbations (PEx) in cystic fibrosis (CF) is essential to minimise lung damage and reduce morbidity and mortality. Spirometry, the standard tool for lung function assessment in adult people with CF (pwCF), has limitations. Forced Oscillometry Technique (FOT) is an effort-independent method that assesses small airways disease and has been validated in other respiratory conditions. This study evaluated the feasibility and acceptability of implementing FOT during treatment for PEx in adult pwCF.  \nMethods: Twelve adult pwCF underwent FOT and spirometry at the start and end of PEx treatment, and at clinically convenient intervals. FOT was also measured before and after physiotherapy-directed airway clearance. A questionnaire assessed patient satisfaction with FOT.  \nResults: All patients had spirometry below baseline at PEx onset and small airways dysfunction on FOT. Treatment was associated with improvements in median FEV1pp (5.1%, p = 0.050) and X5 (0.2 cm H2O/L/s, p = 0.023), with a significant association between FEV1pp and X5 (p = 0.004). There was no significant FOT change after airway clearance. Patients rated FOT more favourably than spirometry.  \nDiscussion: FOT is feasible, well-tolerated, and may complement spirometry in assessing adult pwCF during PEx. Further studies are warranted.  \nKeywords  \ncystic fibrosis, pulmonary exacerbation, oscillometry  \nReceived: 22 July 2025; accepted: 17 December 2025  \nIntroduction  \nCystic fibrosis (CF) is a genetically inherited, life-limiting disease, characterised by chronic pulmonary infection and inflammation. Pulmonary exacerbations (PEx) of CF associated bronchiectasis are associated with progressive lung damage, increased patient morbidity and mortality, and decreased quality of life.1 Whilst prevention, early detection, and treatment are crucial in minimising progressive loss of function in lung tissue and improving patient survival, there are no universally agreed methods of monitoring clinical response to treatment nor guiding treatment  \n1 Thoracic Medicine, The Prince Charles Hospital, Chermside, QLD, Australia  \n2School of Medicine, University of Queensland, Herston, QLD, Australia 3Physiotherapy Department, The Prince Charles Hospital, Chermside, QLD, Australia  \n4School of Allied Health, Australian Catholic University, Banyo, QLD, Australia  \n5QIMR Berghofer Medical Research Institute, Herston, QLD, Australia  \nCorresponding author:  \nJames Nolan, School of Medicine, University of Queensland, Mayne Medical Building, 288 Herston Rd, Herston, QLD 4006, Australia.  \nEmail: [j.nolan@uq.edu.au](j.nolan@uq.edu.au)  \nCreative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons  \nAttribution-NonCommercial 4.0 License ([https://creativecommons.org/licenses/by-nc/4.0/](https://creativecommons.org/licenses/by-nc/4.0/)) which permits non-commercial use,  \nreproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages ([https://us.sagepub.com/en-us/nam/open-access-at-sage](https://us.sagepub.com/en-us/nam/open-access-at-sage)).  \nmodalities and therapy duration.2 This uncertainty is further complicated by the advent of cystic fibrosis transmembrane conductance regulator (CFTR) modulator therap","cbCain8qP66Vreim","https://ap.wps.com/l/cbCain8qP66Vreim","pdf",598279,"English","# Abstract\n# Introduction\n# Methods\n# Results\n# Discussion","[{\"question\":\"Why is forced oscillometry technique (FOT) considered for monitoring pulmonary exacerbations in adults with cystic fibrosis?\",\"answer\":\"Spirometry is limited in sensitivity for small airways changes, and forced expiratory manoeuvres can be unpopular when patients are unwell. FOT is effort-independent and targets small airway disease.\"},{\"question\":\"What did the study assess during pulmonary exacerbation treatment?\",\"answer\":\"It assessed feasibility and acceptability by measuring FOT and spirometry at PEx onset and end, plus at convenient intervals, and by measuring FOT before and after physiotherapy-directed airway clearance.\"},{\"question\":\"What were the key findings regarding lung function and patient preferences?\",\"answer\":\"FOT showed small airways dysfunction at PEx onset, treatment was associated with improvements in FEV1pp and X5, and there was no significant FOT change after airway clearance. Patients rated FOT more favourably than spirometry.\"}]","Forced oscillometry technique in the assessment of adults with cystic fibrosis treated for a pulmonary exacerbation - a pilot feasibility study | PDF",1790724913,23]