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Hydroalcohol extract (HABL) shows the highest phenolic content and stronger inhibitory effects in DPPH, CAP-e, and total antioxidant capacity in ORAC. HABL demonstrates mixed-competitive inhibition of α-amylase and α-glucosidase, and mixed-competitive/competitive inhibition of acetyl- and butyryl-cholinesterase. Seeds are rich in minerals and amino acids, with identified phenolic constituents by HPLC and additional compounds by GC-MS, supporting pharmaceutical and nutraceutical potential.",{"@graph":69,"@context":121},[70,84,104],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/food-bioscience-article-evaluation-of-buchanania-lanzan-seed-antioxidant-antidiabetic-and-anticholinesterase-activities/639362/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":98,"encodingFormat":97,"isAccessibleForFree":99,"interactionStatistic":100},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/food-bioscience-article-evaluation-of-buchanania-lanzan-seed-antioxidant-antidiabetic-and-anticholinesterase-activities/639362.png","ImageObject",300,407,{"name":92,"@type":93},"Finn","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-22",true,{"@type":101,"interactionType":102,"userInteractionCount":4},"InteractionCounter",{"@type":103},"ViewAction",{"@type":105,"mainEntity":106},"FAQPage",[107,113,117],{"name":108,"@type":109,"acceptedAnswer":110},"What activities were evaluated for Buchanania lanzan seeds?","Question",{"text":111,"@type":112},"The study assessed antioxidant, antidiabetic, and anticholinesterase activities using seed hydroalcohol extracts.","Answer",{"name":114,"@type":109,"acceptedAnswer":115},"Why is HABL highlighted in the results?",{"text":116,"@type":112},"Hydroalcohol fraction (HABL) showed the highest phenolic content and demonstrated inhibitory potential in antioxidant and enzyme inhibition assays.",{"name":118,"@type":109,"acceptedAnswer":119},"Which analytical methods were used to identify phytochemical constituents?",{"text":120,"@type":112},"HPLC quantified phenolic compounds, and GC-MS identified additional constituents in HABL.","https://schema.org",{"og:url":83,"og:type":123,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":125,"canonical":83},"index,follow",{"doc_id":127,"site_id":62},639362,1792703269,{"code":4,"msg":5,"data":130},{"doc_id":127,"user_id":131,"nickname":92,"user_avatar":132,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":133,"file_id":134,"file_url":135,"file_type":136,"file_size":137,"view_count":4,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":138,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":128,"read_time":41},34359740700684,"https://ap-avatar.wpscdn.com/avatar/1f400023980c374ae676?_k=1777273430885731487","Food Bioscience 59 (2024) 104135  \nContents lists available at ScienceDirect  \nFood Bioscience  \njournal [homepage:](homepage: www.elsevier.com/locate/fbio)[ www.elsevier.com/locate/fbio](homepage: www.elsevier.com/locate/fbio)  \n| Industrial importance seed kernel of Buchanania lanzan in contributing antioxidant, antidiabetic, and anticholinesterase activities |  |  | |\n| --- | --- | --- | --- |\n| Neelam Meher , Bikash Kisan , Sandeep Kumar Swain , Atish Kumar Sahoo *\u003Cbr>Regional Plant Resource Centre, Medicinal & Aromatic Plant Division, Forest, Environment and Climate Change Department, Govt. of Odisha, Nayapalli, Bhubaneswar, 751015, India |  |  |  |\n| A R T I C L E I N F O |  | A B S T R A C T |  |\n| Keywords: Buchanania lanzan Antidiabetic Anticholinesterase Vit B-Complex Minerals |  | This study aimed to evaluate the antioxidant, antidiabetic, and anticholinesterase activities of Buchanania lanzan Spreng seeds. The therapeutic significance of phytochemicals, minerals, and nutrition were quantified. Hydroalcohol-extract (HABL) possessed the highest phenol contents demonstrated superior inhibitory potential against oxidants in DPPH, CAP-e, and imparted total antioxidant capacity in ORAC test. HABL exhibited mixedcompetitive inhibition against α-amylase and α-glucosidase. HABL exhibited mixed-competitive and competitive inhibition against acetyl-, and butyryl-cholinesterase. Seeds were a rich source of minerals, amino acids, protein, carbohydrates, volatile oil, and energy content. Reported Vit B3 and B6 in seeds were responsible for brain function, and neurotransmitter-synthesis. HPLC quantified phenols (gallic acid, chlorogenic acid, caffeic acid, rutin, and quercetin), and GC-MS identified (Catechol, 2-Hydroxy-5-methylbenzaldehyde, Hexadecanoic acid, methyl ester, n-Hexadecanoic acid, Hexadecanoic acid, ethyl ester, 8-Octadecenoic acid, methyl ester, 9,12-Octadecadienoic acid, ethyl ester,(E)-9-Octadecenoic acid ethyl ester, Heptadecanoic acid, 15-methyl-, ethyl ester, Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, 9-Octadecenoic acid (Z) -, 2-hydroxy-1-(hydroxymethyl)ethyl, and β-Sitosterol) in HABL exhibited antioxidant, antidiabetic, and anticholinesterase activities.\u003Cbr>B. lanzan seeds are given adequate attention for making medicines and dietary supplements in the pharmaceutical and nutraceutical industries. |  |\n\n1. Introduction  \nDiabetes mellitus is a well-known metabolic syndrome that originates from a complete or virtual requirement of insulin and low insulin action, which leads to hyperglycaemia and malformation in the regulation of lipids, proteins, and carbohydrates. Among the different types of diabetes, the most prevalent form is type 2 diabetes mellitus (T2DM) which accounts for 90% of cases. The global prevalence of T2DM is rapidly increasing with more than half a billion affected as a result of aging populations and lifestyle changes (Rocha et al., 2021). Prolonged undiagnosed diabetes or improper management can lead to micro and macrovascular complications such as neuropathies, nephropathies, retinopathies, and cardiomyopathies affecting multiple organs such as heart, blood vessels, nerves, eyes, and kidneys (Rocha et al., 2021). Diabetic neuropathy, a chronic microvascular complication of diabetes, resulting from diffuse and focal nervous system damage leads to significant morbidity and mortality (Verdile et al., 2015). Around half of people with diabetes suffer from neuropathy. Both chronic and acute  \nhyperglycemia cause oxidative stress in the peripheral nervous system, leading to an acceleration of diabetic neuropathic development. Management of diabetes with available allopathic medicines is too expensive as well as and high probability of side effects with limited efficacy. So, phytotherapy is a common complementary, alternative, and popular medicine for the treatment of diabetes (Feldman et al., 2019).  \nBuchanania lanzan Spreng. (Anacardiaceae), is also known as Almondette found i","cbCail6qWrJW8faL","https://ap.wps.com/l/cbCail6qWrJW8faL","pdf",3532799,12,"English","# Introduction\n## Diabetes mellitus background and complications\n## Phytotherapy and rationale for herbal treatment\n## Buchanania lanzan traditional uses\n# List of abbreviations","[{\"question\":\"What activities were evaluated for Buchanania lanzan seeds?\",\"answer\":\"The study assessed antioxidant, antidiabetic, and anticholinesterase activities using seed hydroalcohol extracts.\"},{\"question\":\"Why is HABL highlighted in the results?\",\"answer\":\"Hydroalcohol fraction (HABL) showed the highest phenolic content and demonstrated inhibitory potential in antioxidant and enzyme inhibition assays.\"},{\"question\":\"Which analytical methods were used to identify phytochemical constituents?\",\"answer\":\"HPLC quantified phenolic compounds, and GC-MS identified additional constituents in HABL.\"}]","Food Bioscience - Article - Evaluation of Buchanania lanzan Seed Antioxidant, Antidiabetic and Anticholinesterase Activities | PDF"]