[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-639373-105":3,"detail-sidebar-cat-0-en-105":79,"doc-detail-639373-en":129},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":72,"head_meta":74,"extra_data":76,"updated_unix":78},105,"en","food-bioscience-59-2024-104135-antioxidant-antidiabetic-and-anticholinesterase-activities-of-buchanania-lanzan-seeds","Food Bioscience - 59 (2024) 104135 - Antioxidant, Antidiabetic, and Anticholinesterase Activities of Buchanania lanzan Seeds","","This study evaluates antioxidant, antidiabetic, and anticholinesterase activities of Buchanania lanzan Spreng seeds. Hydroalcohol-extract (HABL) shows the highest phenolic contents and superior inhibitory potential against oxidants in DPPH, CAP-e, and ORAC. HABL demonstrates mixed-competitive inhibition against α-amylase and α-glucosidase, and mixed-competitive plus competitive inhibition against acetyl- and butyryl-cholinesterase. Seeds are rich in minerals, amino acids, protein, carbohydrates, volatile oil, and energy; HPLC and GC-MS quantify bioactive phenols and phytoconstituents.",{"@graph":14,"@context":71},[15,34,54],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/research-report/","Research & Report",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/food-bioscience-59-2024-104135-antioxidant-antidiabetic-and-anticholinesterase-activities-of-buchanania-lanzan-seeds/639373/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":48,"encodingFormat":47,"isAccessibleForFree":49,"interactionStatistic":50},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/food-bioscience-59-2024-104135-antioxidant-antidiabetic-and-anticholinesterase-activities-of-buchanania-lanzan-seeds/639373.png","ImageObject",300,407,{"name":42,"@type":43},"Finn","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-22",true,{"@type":51,"interactionType":52,"userInteractionCount":4},"InteractionCounter",{"@type":53},"ViewAction",{"@type":55,"mainEntity":56},"FAQPage",[57,63,67],{"name":58,"@type":59,"acceptedAnswer":60},"What extract was tested for bioactivity in the study?","Question",{"text":61,"@type":62},"The study tested the hydroalcohol-extract (HABL) of Buchanania lanzan Spreng seeds for antioxidant, antidiabetic, and anticholinesterase activities.","Answer",{"name":64,"@type":59,"acceptedAnswer":65},"Which antioxidant and enzyme inhibition assays were used?",{"text":66,"@type":62},"Antioxidant effects were assessed using DPPH, CAP-e, and ORAC, while antidiabetic activity involved inhibition of α-amylase and α-glucosidase; anticholinesterase activity involved acetyl- and butyryl-cholinesterase.",{"name":68,"@type":59,"acceptedAnswer":69},"How were the main phytochemicals identified and quantified?",{"text":70,"@type":62},"Phenolic constituents were quantified by HPLC, and other compounds were identified using GC-MS in the HABL fraction.","https://schema.org",{"og:url":32,"og:type":73,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":75,"canonical":32},"index,follow",{"doc_id":77,"site_id":7},639373,1792703302,{"code":4,"msg":80,"data":81},"success",[82,86,90,94,99,104,109,113,118,121,125],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":83,"show_sort_weight":84,"slug":85},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":87,"show_sort_weight":88,"slug":89},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":91,"show_sort_weight":92,"slug":93},"Exam",70,"exam",{"id":95,"doc_module":4,"doc_module_name":25,"category_name":96,"show_sort_weight":97,"slug":98},5,"Comic",60,"comic",{"id":100,"doc_module":4,"doc_module_name":25,"category_name":101,"show_sort_weight":102,"slug":103},6,"Technology",50,"technology",{"id":105,"doc_module":4,"doc_module_name":25,"category_name":106,"show_sort_weight":107,"slug":108},7,"Healthcare",40,"healthcare",{"id":110,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":111,"slug":112},8,30,"research-report",{"id":114,"doc_module":4,"doc_module_name":25,"category_name":115,"show_sort_weight":116,"slug":117},9,"Religion & Spirituality",20,"religion-spirituality",{"id":116,"doc_module":4,"doc_module_name":25,"category_name":119,"show_sort_weight":116,"slug":120},"World Cup","world-cup",{"id":122,"doc_module":4,"doc_module_name":25,"category_name":123,"show_sort_weight":122,"slug":124},10,"Lifestyle","lifestyle",{"id":126,"doc_module":4,"doc_module_name":25,"category_name":127,"show_sort_weight":95,"slug":128},19,"General","general",{"code":4,"msg":80,"data":130},{"doc_id":77,"user_id":131,"nickname":42,"user_avatar":132,"doc_module":4,"category_id":110,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":133,"file_id":134,"file_url":135,"file_type":136,"file_size":137,"view_count":4,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":138,"language":139,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":12,"update_tm":78,"read_time":111},34359740700684,"https://ap-avatar.wpscdn.com/avatar/1f400023980c374ae676?_k=1777273430885731487","Food Bioscience 59 (2024) 104135  \nContents lists available at ScienceDirect  \nFood Bioscience  \njournal [homepage:](homepage: www.elsevier.com/locate/fbio)[ www.elsevier.com/locate/fbio](homepage: www.elsevier.com/locate/fbio)  \n| Industrial importance seed kernel of Buchanania lanzan in contributing antioxidant, antidiabetic, and anticholinesterase activities |  |  | |\n| --- | --- | --- | --- |\n| Neelam Meher , Bikash Kisan , Sandeep Kumar Swain , Atish Kumar Sahoo *\u003Cbr>Regional Plant Resource Centre, Medicinal & Aromatic Plant Division, Forest, Environment and Climate Change Department, Govt. of Odisha, Nayapalli, Bhubaneswar, 751015, India |  |  |  |\n| A R T I C L E I N F O |  | A B S T R A C T |  |\n| Keywords: Buchanania lanzan Antidiabetic Anticholinesterase Vit B-Complex Minerals |  | This study aimed to evaluate the antioxidant, antidiabetic, and anticholinesterase activities of Buchanania lanzan Spreng seeds. The therapeutic significance of phytochemicals, minerals, and nutrition were quantified. Hydroalcohol-extract (HABL) possessed the highest phenol contents demonstrated superior inhibitory potential against oxidants in DPPH, CAP-e, and imparted total antioxidant capacity in ORAC test. HABL exhibited mixedcompetitive inhibition against α-amylase and α-glucosidase. HABL exhibited mixed-competitive and competitive inhibition against acetyl-, and butyryl-cholinesterase. Seeds were a rich source of minerals, amino acids, protein, carbohydrates, volatile oil, and energy content. Reported Vit B3 and B6 in seeds were responsible for brain function, and neurotransmitter-synthesis. HPLC quantified phenols (gallic acid, chlorogenic acid, caffeic acid, rutin, and quercetin), and GC-MS identified (Catechol, 2-Hydroxy-5-methylbenzaldehyde, Hexadecanoic acid, methyl ester, n-Hexadecanoic acid, Hexadecanoic acid, ethyl ester, 8-Octadecenoic acid, methyl ester, 9,12-Octadecadienoic acid, ethyl ester,(E)-9-Octadecenoic acid ethyl ester, Heptadecanoic acid, 15-methyl-, ethyl ester, Hexadecanoic acid, 2-hydroxy-1-(hydroxymethyl)ethyl ester, 9-Octadecenoic acid (Z) -, 2-hydroxy-1-(hydroxymethyl)ethyl, and β-Sitosterol) in HABL exhibited antioxidant, antidiabetic, and anticholinesterase activities.\u003Cbr>B. lanzan seeds are given adequate attention for making medicines and dietary supplements in the pharmaceutical and nutraceutical industries. |  |\n\n1. Introduction  \nDiabetes mellitus is a well-known metabolic syndrome that originates from a complete or virtual requirement of insulin and low insulin action, which leads to hyperglycaemia and malformation in the regulation of lipids, proteins, and carbohydrates. Among the different types of diabetes, the most prevalent form is type 2 diabetes mellitus (T2DM) which accounts for 90% of cases. The global prevalence of T2DM is rapidly increasing with more than half a billion affected as a result of aging populations and lifestyle changes (Rocha et al., 2021). Prolonged undiagnosed diabetes or improper management can lead to micro and macrovascular complications such as neuropathies, nephropathies, retinopathies, and cardiomyopathies affecting multiple organs such as heart, blood vessels, nerves, eyes, and kidneys (Rocha et al., 2021). Diabetic neuropathy, a chronic microvascular complication of diabetes, resulting from diffuse and focal nervous system damage leads to significant morbidity and mortality (Verdile et al., 2015). Around half of people with diabetes suffer from neuropathy. Both chronic and acute  \nhyperglycemia cause oxidative stress in the peripheral nervous system, leading to an acceleration of diabetic neuropathic development. Management of diabetes with available allopathic medicines is too expensive as well as and high probability of side effects with limited efficacy. So, phytotherapy is a common complementary, alternative, and popular medicine for the treatment of diabetes (Feldman et al., 2019).  \nBuchanania lanzan Spreng. (Anacardiaceae), is also known as Almondette found i","cbCail7eIlfkwgXl","https://ap.wps.com/l/cbCail7eIlfkwgXl","pdf",3516381,12,"English","# Introduction\n## Diabetes and oxidative stress\n## Phytotherapy as complementary treatment\n## Buchanania lanzan in traditional medicine\n# List of abbreviations","[{\"question\":\"What extract was tested for bioactivity in the study?\",\"answer\":\"The study tested the hydroalcohol-extract (HABL) of Buchanania lanzan Spreng seeds for antioxidant, antidiabetic, and anticholinesterase activities.\"},{\"question\":\"Which antioxidant and enzyme inhibition assays were used?\",\"answer\":\"Antioxidant effects were assessed using DPPH, CAP-e, and ORAC, while antidiabetic activity involved inhibition of α-amylase and α-glucosidase; anticholinesterase activity involved acetyl- and butyryl-cholinesterase.\"},{\"question\":\"How were the main phytochemicals identified and quantified?\",\"answer\":\"Phenolic constituents were quantified by HPLC, and other compounds were identified using GC-MS in the HABL fraction.\"}]","Food Bioscience - 59 (2024) 104135 - Antioxidant, Antidiabetic, and Anticholinesterase Activities of Buchanania lanzan Seeds | PDF"]