[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-115976-en":3,"doc-seo-115976-105":31,"detail-sidebar-cat-0-en-105":92},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":20,"is_deleted":4,"is_public":21,"is_downloadable":21,"audit_status":21,"page_count":22,"language":23,"language_code":24,"site_id":25,"html_lang":24,"table_of_contents":26,"faqs":27,"seo_title":28,"seo_description":14,"update_tm":29,"read_time":30},115976,962085570644,"Evangeline","https://ap-avatar.wpscdn.com/davatar_994ba38a5ba835b3df7d355c54d3ed8d",7,"Healthcare","Fluid, Electrolyte, and Acid-Base Physiology - A Problem-Based Approach","Fluid, electrolyte, and acid-base physiology presents the regulation of body water, key electrolytes, and blood pH through an explicitly problem-based learning framework. Each chapter opens by grounding core physiology and biochemistry principles, then revisits more classical material with a distinct clinical emphasis on acid-base, salt and water, and potassium homeostasis. The book’s later chapter sections highlight integrative physiology using deductive reasoning to surface controversies and uncertainties, supporting critical evaluation of buffering, renal acid-base contributions, and the rationale behind the normal blood pH value.","Fluid,Electrolyte,and Acid-BasePhysiology  \n# A PROBLEM-BASED APPROACH\n\nHalperin,Kamel,&Goldstein  \n2019.5.  \n%  \n29 NOV 2013  \nFluid,Electrolyte,and Acid-Base Physiology  \n# Fluid,Electrolyte,andAcid-Base PhysiologyA Problem-Based Approach\n\nMitchell L.Halperin,MD,FRCPC  \nST.MICHAEL's HoSPITALUNIVERSITY OF ToRONTOToRONTO,CANADA  \nKamel S.Kamel,MD,FRCPC  \nST.MICHAEL's HosPITALUNIVERSITY OF ToRONTOToRONTO,CANADA  \nMarc B.Goldstein,MD,FRCPC  \nST.MICHAEL's HosPITALUNIVERSITY OF ToRONTOToRONTO,CANADA  \nSAUNDERS  \nELSEVIER  \n1600 John F.Kennedy BoulevardSuite 1800Philadelphia,PA 19103-2899  \n# FLUID,ELECTROLYTE,AND ACID-BASE PHYSIOLOGY:A PROBLEM-BASED APPROACHISBN:978-1-4160-2442-2Copyright O 2010,1999,1994,1988 by Saunders,an imprint of Elsevier Inc.\n\nAll rights reserved.No part of this publication may be reproduced or transmitted inany form or by any means,electronic or mechanical,including photocopying,record-ing,or any information storage and retrievalsystem,without permission in writingfrom the publisher.Permissions may be sought directly from Elsevier's Rights Depart-ment:phone:(+1)2152393804(US)or(+44)1865843830(UK);fax:(+44)1865853333,e-mail:healthpermissions@elsevier.com.You may also complete your requeston-line via the Elsevier website at http://www.elsevier.com/permissions.  \nNotice  \nKnowledge and best practice in this field are constantly changing.As new researchand experience broaden our knowledge,changes in practice,treatment,and drugtherapy may become necessary or appropriate.Readers are advised to check themost current information provided (i)on procedures featured or(ii)by the man-ufacturer of each product to be administered,to verify the recommended doseor formula,the method and duration of administration,and contraindications.It is the responsibility of the practitioners,relying on their own experience andknowledge of the patient,to make diagnoses,to determine dosages and the besttreatment for each individual patient,and to take all appropriate safety precau-tions.To the fullest extent of the law,neither the Publisher nor the Authors assumeany liability for any injury and/or damage to persons or property arising out of orrelated to any use of the material contained in this book.  \nLibrary of Congress Cataloging-in-Publication Data  \nHalperin,M.L.(Mitchell L.)  \n# Fluid,electrolyte,and acid-base physiology:a problem-basedapproach/Mitchell L.Halperin,Kamel S.Kamel,Marc B.Goldstein.—4th ed.\n\np.;cm.  \nIncludes bibliographical references and index.  \nISBN 978-1-4160-2442-2  \n1.Water-electrolyte imbalances.2.Acid-base imbalances.  \n3.Water-electrolyte imbalances—Case studies.4.Acid-base  \nimbalances—Case studies.I.Kamel,Kamel S.II.Goldstein,Marc B.III.Title.  \n[DNLM:1.Acid-Base Imbalance—physiopathology.2.Water-Electrolyte  \nImbalance—physiopathology.3.Acid-Base Imbalance—diagnosis.  \n4.Potassium—metabolism.5.Water-Electrolyte Imbalance—diagnosis.WD220 H195f2009]  \nRC630.H342009  \n616.3'992—dc22  \nAcquisitions Editor:Adrianne Brigido  \nDevelopmental Editor:Angela Norton  \nProject Manager:Bryan Hayward  \nDesign Direction:Steven Stave  \nPrinted in the United States of America  \nLast digit is the print number:987654321  \nThe Publisher  \n2008020019  \n\n| Working together to grow  \u003Cbr>libraries in developing countries  \u003Cbr>www.elsevier.com |www.bookaid.org |www.sabre.org   |\n| --- |\n| ELSEVTER BOOKAD Sabre Foundation   |\n\nTo Brenda,Marylin,and Ellen:We are indeed extremelygrateful for your patience;your strong,unwavering support;and your understanding.  \nhere has been a long interval between this,the fourth editionof Fluid,Electrolyte,and Acid-Base Physiology,and the thirdedition of the book.This delay was caused,in part,by ourdecision to virtually rewrite the text,which resulted from our collabo-ration with Professor Kamel S.Kamel,whose input has had a majorimpact on the content of the current edition.A creative and criticalindividual who is highly motivated to understand“why things hap-pen in biology,\"Dr.Kamel encouraged u","cbCaivSzzLSxJ5mt","https://ap.wps.com/l/cbCaivSzzLSxJ5mt","pdf",44952736,4,1,620,"English","en",105,"# Fluid, Electrolyte, and Acid-Base Physiology - A Problem-Based Approach\n## Principles-based chapter structure\n## Classical content with clinical emphasis\n## Integrative physiology and deductive analysis\n## Acid-base buffering and base balance\n## Renal contribution and kidney stone risk\n## Why normal blood pH is 7.40","[{\"question\":\"What learning structure does the book use for each chapter?\",\"answer\":\"Each chapter begins with a chapter on principles of physiology and biochemistry, followed by more classical aspects with a focused clinical perspective, and ends with integrative physiology using deductive reasoning.\"},{\"question\":\"How does the book approach controversies in acid-base physiology?\",\"answer\":\"The text raises questions and discourages simple repetition of established dogma, pointing readers to where disagreements and uncertainties exist even when not all readers accept the explanations.\"},{\"question\":\"What emphasis does the book place on buffering and renal acid-base handling?\",\"answer\":\"It encourages critical evaluation of “good” versus “bad” buffering, adds a strong emphasis on base balance, and stresses that renal acid-base contributions must avoid increasing kidney stone risk, including maintaining urine pH near 6 and appropriate citrate concentration.\"}]","Fluid, Electrolyte, and Acid-Base Physiology - 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