[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-406383-105":3,"doc-detail-406383-en":81,"detail-sidebar-cat-0-en-105":99},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","feasibility-and-safety-of-enhanced-recovery-after-surgery-in-elderly-patients-with-gastric-cancer","Feasibility and safety of enhanced recovery after surgery in elderly patients with gastric cancer","","The enhanced recovery after surgery (ERAS) perioperative framework is widely reported to improve surgical outcomes and reduce financial burdens, yet its applicability in elderly gastric cancer patients requires further validation. A retrospective study evaluated 161 patients undergoing ERAS between January 2022 and January 2024, comparing young (\u003C65) and elderly (≥65) groups. Findings showed higher complication incidence in the elderly group, but no significant differences in many ERAS completion, ventilation, hospital stay, key leakage/infection outcomes, inflammatory markers, or 30-day mortality.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/feasibility-and-safety-of-enhanced-recovery-after-surgery-in-elderly-patients-with-gastric-cancer/406383/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/feasibility-and-safety-of-enhanced-recovery-after-surgery-in-elderly-patients-with-gastric-cancer/406383.png","ImageObject",300,407,{"name":42,"@type":43},"Đào","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-31","2026-09-28",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",6,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What is the study’s main objective?","Question",{"text":63,"@type":64},"To validate the feasibility and safety of the ERAS protocol in elderly patients with gastric cancer and strengthen its evidence base.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"How was the study designed and who were the participants?",{"text":68,"@type":64},"It was a retrospective analysis of 161 gastric cancer patients who underwent ERAS from January 2022 to January 2024, including 79 young patients (\u003C65) and 82 elderly patients (≥65).",{"name":70,"@type":61,"acceptedAnswer":71},"Were there differences in postoperative outcomes between elderly and young groups?",{"text":72,"@type":64},"The elderly group had a significantly higher overall incidence of complications and specific comorbidities (hypertension, diabetes, respiratory disease, heart disease). However, many ERAS-related completion and postoperative outcomes (including key leakage/infection types, ventilation time, hospital stay, inflammatory markers on days 1 and 3) showed no significant differences, and no deaths occurred within 30 days in either group.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},406383,1790695196,{"code":4,"msg":82,"data":83},"success",{"doc_id":79,"user_id":84,"nickname":42,"user_avatar":85,"doc_module":4,"category_id":86,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":87,"file_id":88,"file_url":89,"file_type":90,"file_size":91,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":92,"language":93,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":94,"faqs":95,"seo_title":96,"seo_description":12,"update_tm":97,"read_time":98,"preview_page_count":4},1374402968488,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0",7,"| W | J | G | World Journal of\u003Cbr>Gastroenterology |\n| --- | --- | --- | --- |\n\nSubmit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Gastroenterol 2025 December 21; 31(47): 113331  \nDOI: 10.3748/wjg.v31.i47.113331 ISSN 1007-9327 (print) ISSN 2219-2840 (online)  \nORIGINAL ARTICLE  \nRetrospective Study  \nFeasibility and safety of enhanced recovery after surgery in elderly patients with gastric cancer  \nJia-Yu Li, Miao-Miao Ge, Hua-Feng Pan, Gang Wang, Zhi-Wei Jiang  \nSpecialty type: Surgery  \nProvenance and peer review:  \nUnsolicited article; Externally peer reviewed.  \nPeer-review model: Single blind  \nPeer-review report’s classification Scientific Quality: Grade A, Grade B, Grade C  \nNovelty: Grade B, Grade C, Grade D  \nCreativity or Innovation: Grade A, Grade C, Grade D  \nScientific Significance: Grade B, Grade C, Grade D  \nP-Reviewer: Sun GY, PhD, Associate Research Scientist, China; Wan HJ, MD, PhD, Vice Director, China  \nReceived: August 22, 2025  \nRevised: September 22, 2025  \nAccepted: October 29, 2025  \nPublished online: December 21, 2025  \nProcessing time: 119 Days and 17.9 Hours  \nJia-Yu Li, Miao-Miao Ge, Hua-Feng Pan, Gang Wang, Zhi-Wei Jiang, Department of General Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210023, Jiangsu Province, China  \nCo-corresponding authors: Hua-Feng Pan and Gang Wang.  \nCorresponding author: Gang Wang, MD, Associate Professor, Department of General Surgery, Affiliated Hospital of Nanjing University of Chinese Medicine, No. 155 Hanzhong Road, Qinhuai District, Nanjing 210023, Jiangsu Province, [China.](China. gangwang82@163.com)[ gangwang82@163.com](China. gangwang82@163.com)  \nAbstract  \nBACKGROUND  \nThe enhanced recovery after surgery (ERAS) perioperative management framework has been well-documented to improve surgical outcomes and alleviate financial burdens for patients. Against the backdrop of a rapidly aging global population, the incidence of gastric cancer (GC) among elderly individuals continues to increase.  \nAIM  \nTo validate the feasibility and safety of the ERAS protocol in elderly GC patients, thereby enhancing its evidence-based medical foundation.  \nMETHODS  \nA retrospective analysis of 161 GC patients who underwent ERAS between January 2022 and January 2024 was conducted. The subjects included 79 young patients (\u003C 65 years) and 82 elderly patients (≥ 65 years) . The rates of ERAS compliance, postoperative ventilation time, postoperative hospital stay, reoperation rate, mortality rate, postoperative inflammatory markers C-reactive protein (CRP), white blood cells (WBCs), IL-2, IL-6, and the rate of postoperative complications (anastomotic leakage, incision infection, pulmonary infection) were compared between these two groups.  \nRESULTS  \nThe incidence of complications in the elderly group was significantly higher than that in the young group, and included hypertension (P = 0.002), diabetes (P = 0.005), respiratory disease (P = 0.034), and heart disease (P = 0.016) . In terms of American Society of Anesthesiologists (ASA) grading indicators, the overall ASA grade in the elderly group was biased toward grade II, which was significantly  \n WJG  [https://www.wjgnet.com](https://www.wjgnet.com) 1 December 21, 2025  Volume 31  Issue 47   \nLi JY et al. Application of ERAS in elderly patients  \nhigher than that in the young group (P \u003C 0.001) . There was no significant difference in sex, body mass index, preoperative albumin, preoperative WBCs, TNM classification, differentiation, number of lymph node metastasis, and preoperative IL-6 between the two groups. There were no significant differences between the two groups in terms of operative method, surgical approach, conversion to open surgery, operation time, intraoperative bleeding volume, and number of lymph nodes dissected (all P values > 0.05) . There were no significant differences between the two groups in ERAS completion rate, reoperation, postoperative ","cbCaic7v6BULaO9s","https://ap.wps.com/l/cbCaic7v6BULaO9s","pdf",438203,10,"English","# Abstract\n## Background\n## Aim\n## Methods\n## Results\n## Conclusion\n# Introduction\n## Background on gastric cancer burden","[{\"question\":\"What is the study’s main objective?\",\"answer\":\"To validate the feasibility and safety of the ERAS protocol in elderly patients with gastric cancer and strengthen its evidence base.\"},{\"question\":\"How was the study designed and who were the participants?\",\"answer\":\"It was a retrospective analysis of 161 gastric cancer patients who underwent ERAS from January 2022 to January 2024, including 79 young patients (\\u003c65) and 82 elderly patients (≥65).\"},{\"question\":\"Were there differences in postoperative outcomes between elderly and young groups?\",\"answer\":\"The elderly group had a significantly higher overall incidence of complications and specific comorbidities (hypertension, diabetes, respiratory disease, heart disease). However, many ERAS-related completion and postoperative outcomes (including key leakage/infection types, ventilation time, hospital stay, inflammatory markers on days 1 and 3) showed no significant differences, and no deaths occurred within 30 days in either group.\"}]","Feasibility and safety of enhanced recovery after surgery in elderly patients with gastric cancer | PDF",1790565259,25,{"code":4,"msg":82,"data":100},[101,105,109,113,118,122,125,130,135,138,141],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":102,"show_sort_weight":103,"slug":104},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":106,"show_sort_weight":107,"slug":108},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":110,"show_sort_weight":111,"slug":112},"Exam",70,"exam",{"id":114,"doc_module":4,"doc_module_name":25,"category_name":115,"show_sort_weight":116,"slug":117},5,"Comic",60,"comic",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":119,"show_sort_weight":120,"slug":121},"Technology",50,"technology",{"id":86,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":123,"slug":124},40,"healthcare",{"id":126,"doc_module":4,"doc_module_name":25,"category_name":127,"show_sort_weight":128,"slug":129},8,"Research & Report",30,"research-report",{"id":131,"doc_module":4,"doc_module_name":25,"category_name":132,"show_sort_weight":133,"slug":134},9,"Religion & Spirituality",20,"religion-spirituality",{"id":133,"doc_module":4,"doc_module_name":25,"category_name":136,"show_sort_weight":133,"slug":137},"World Cup","world-cup",{"id":92,"doc_module":4,"doc_module_name":25,"category_name":139,"show_sort_weight":92,"slug":140},"Lifestyle","lifestyle",{"id":142,"doc_module":4,"doc_module_name":25,"category_name":143,"show_sort_weight":114,"slug":144},19,"General","general"]