[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-338377-105":59,"doc-detail-338377-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","fatty-liver-index-as-an-independent-predictor-of-all-cause-and-disease-specific-mortality-read-online-free","Fatty liver index as an independent predictor of all-cause and disease-specific mortality - read online free","","Fatty liver index (FLI), a noninvasive marker for hepatic steatosis, is evaluated for its ability to predict future mortality outcomes. Data from National Health and Nutrition Examination Survey III (1988–1994) were linked to Public-Use Mortality Files, yielding 11,297 participants followed for a median of 26.25 years. Cox proportional hazards and Fine and Gray’s competing-risk models quantify FLI’s associations with all-cause and cause-specific deaths.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/fatty-liver-index-as-an-independent-predictor-of-all-cause-and-disease-specific-mortality-read-online-free/338377/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/fatty-liver-index-as-an-independent-predictor-of-all-cause-and-disease-specific-mortality-read-online-free/338377.png","ImageObject",300,407,{"name":92,"@type":93},"Skyler","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-27","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",12,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What is the main purpose of this study?","Question",{"text":113,"@type":114},"To assess the prognostic value of the fatty liver index (FLI) for predicting all-cause mortality and disease-specific mortality.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How were FLI and mortality risk associations evaluated?",{"text":118,"@type":114},"The study used Cox proportional hazards models for all-cause mortality and Fine and Gray’s models for disease-specific mortality under competing risks.",{"name":120,"@type":111,"acceptedAnswer":121},"What did the study find about FLI levels and mortality?",{"text":122,"@type":114},"FLI ≥ 60 was independently associated with higher risk of all-cause mortality and increased mortality from malignant neoplasms, diabetes, and cardiovascular diseases compared with FLI \u003C 30.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},338377,1790251492,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":145,"read_time":146},2336464648746,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","Original article    \nFatty liver index as an independent predictor of all-cause and disease-specific mortality  \nRuixin Zhanga ,* , Shuhao Rena ,* , Hongfei Mib ,c ,* , Meixia Wangd , Tingjuan Heb ,c , Renyan Zhanga , Wei Jiange ,† and Chenghao Sub ,c ,†  \n\n| Purpose: This study aims to assess the prognostic value of the fatty liver index (FLI), a noninvasive tool for hepatic steatosis assessment, in predicting all-cause and disease-specific mortality.\u003Cbr>Methods: We linked data from the National Health and Nutrition Examination Survey III (1988–1994) with Public-Use Mortality |\n| --- |\n| Files, forming a cohort of 11 297 participants with a median follow-up period of 26.25 years. Cox proportional hazards models were used to evaluate the association between FLI and all-cause mortality, while Fine and Gray’s models assessed the relationship between FLI and disease-specific mortality.\u003Cbr>Results: The FLI ≥ 60 was independently associated with an increased risk of all-cause mortality (hazard ratio = 1.24,\u003Cbr>P \u003C 0.001), as well as mortality from malignant neoplasms (hazard ratio = 1. 18, P = 0.048), diabetes (hazard ratio = 2.62, P = 0.001), and cardiovascular diseases (CVDs) (hazard ratio = 1. 18, P = 0.018), compared to FLI \u003C 30. No significant associations were found with Alzheimer’s disease, influenza and pneumonia, chronic lower respiratory diseases, or renal disorders. Subgroup analyses indicated that individuals who were females aged 40–60 (hazard ratio = 1.67, P = 0.003), nonoverweight (hazard ratio = 1.75, P = 0.007), or without abdominal obesity (hazard ratio = 1.75, P = 0.007) exhibited a stronger association between FLI ≥ 60 and all-cause mortality.\u003Cbr>Conclusion: These findings support the prognostic value of the FLI for predicting mortality from all causes, malignant neoplasms, diabetes, and CVDs. Targeted attention is needed in postmenopausal women, non-overweight, and nonabdominally obese populations. Eur J Gastroenterol Hepatol 36 : 1453–1463\u003Cbr>Graphical abstract: [http://links.lww.com/EJGH/B66](http://links.lww.com/EJGH/B66)\u003Cbr> Copyright © 2024 The Author(s) . Published by Wolters Kluwer Health, Inc.  |\n\nIntroduction  \nNonalcoholic fatty liver disease (NAFLD) is estimated to have a global prevalence of approximately 30% [1] and has become the leading cause of chronic liver disease  \nEuropean Journal of Gastroenterology & Hepatology 2024, 36:1453–1463 Keywords: fatty liver index, Fine and Gray’s model, hepatic steatosis, mortality, prognostic value  \naSchool of Public Health, Xiamen University, bDepartment of Public Health, Zhongshan Hospital, Fudan University (Xiamen Branch), cDepartment of Public Health, Xiamen Clinical Research Center for Cancer Therapy, dDepartment of Hospital Infection Control and eDepartment of Gastroenterology and Hepatology, Zhongshan Hospital, Fudan University (Xiamen Branch), Xiamen, Fujian, China Correspondence to Chenghao Su, PhD, Department of Public Health, Zhongshan Hospital, Fudan University (Xiamen Branch), Xiamen 361015, Fujian, China  \nTel: +86 05923569152; E-mail: [13799752802@163.com](13799752802@163.com)  \n*Ruixin Zhang, Shuhao Ren, and Hongfei Mi contributed equally to the writing of this article.  \n†Wei Jiang and Chenghao Su are joint senior authors and contributed equally to the writing of this article.  \nThis is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBYNC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.  \nReceived 6 May 2024 Accepted 13 September 2024.  \nSupplemental Digital Content is available for this article. Direct URL citations appear in the printed text and are provided in the HTML and PDF versions of this article on the journal’s website, [www.eurojgh.com](www.eurojgh.com).  \nworldwide [2] . A rapid increase in the incidence and morta","cbCaikJWz303GHIl","https://ap.wps.com/l/cbCaikJWz303GHIl","pdf",635197,11,"English","# Purpose\n## Methods\n# Results\n# Conclusion\n# Keywords","[{\"question\":\"What is the main purpose of this study?\",\"answer\":\"To assess the prognostic value of the fatty liver index (FLI) for predicting all-cause mortality and disease-specific mortality.\"},{\"question\":\"How were FLI and mortality risk associations evaluated?\",\"answer\":\"The study used Cox proportional hazards models for all-cause mortality and Fine and Gray’s models for disease-specific mortality under competing risks.\"},{\"question\":\"What did the study find about FLI levels and mortality?\",\"answer\":\"FLI ≥ 60 was independently associated with higher risk of all-cause mortality and increased mortality from malignant neoplasms, diabetes, and cardiovascular diseases compared with FLI \\u003c 30.\"}]","Fatty liver index as an independent predictor of all-cause and disease-specific mortality - read online free | PDF",1790023343,28]