[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-444053-105":3,"detail-sidebar-cat-0-en-105":80,"doc-detail-444053-en":130},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":73,"head_meta":75,"extra_data":77,"updated_unix":79},105,"en","fatal-spontaneous-rebleeding-of-subdural-haematoma-following-covid-19-infection-a-case-report","Fatal Spontaneous Rebleeding of Subdural Haematoma Following COVID-19 Infection - A Case Report","","COVID-19 is associated with neurological complications, including intracranial haemorrhage, yet spontaneous rebleeding of pre-existing subdural haematomas triggered by infection remains extremely rare. An 88-year-old woman with rheumatoid arthritis and acute-on-chronic subdural haematoma after a fall was managed conservatively due to age and comorbidities. After seven days’ stability, COVID-19 was confirmed by PCR screening; within 24 hours she deteriorated neurologically from a Glasgow Coma Scale of 15 to 3. Imaging showed worsening subdural haemorrhage with increased 12 mm midline shift and acute rebleeding. Despite supportive care, she died 10 days later, highlighting a temporal fatal association possibly involving vascular injury, neuroinflammation, and coagulopathy, warranting heightened surveillance.",{"@graph":14,"@context":72},[15,34,55],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/research-report/","Research & Report",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/fatal-spontaneous-rebleeding-of-subdural-haematoma-following-covid-19-infection-a-case-report/444053/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/fatal-spontaneous-rebleeding-of-subdural-haematoma-following-covid-19-infection-a-case-report/444053.png","ImageObject",300,407,{"name":42,"@type":43},"Melati","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-04","2026-09-29",true,{"@type":52,"interactionType":53,"userInteractionCount":30},"InteractionCounter",{"@type":54},"ViewAction",{"@type":56,"mainEntity":57},"FAQPage",[58,64,68],{"name":59,"@type":60,"acceptedAnswer":61},"How quickly did the patient deteriorate after COVID-19 diagnosis?","Question",{"text":62,"@type":63},"Within 24 hours she experienced catastrophic neurological deterioration, with the Glasgow Coma Scale declining from 15 to 3.","Answer",{"name":65,"@type":60,"acceptedAnswer":66},"What imaging findings confirmed acute rebleeding?",{"text":67,"@type":63},"Imaging confirmed worsening subdural haemorrhage with increased midline shift (12 mm) and acute rebleeding.",{"name":69,"@type":60,"acceptedAnswer":70},"What treatment approach was chosen for the subdural haematoma?",{"text":71,"@type":63},"Conservative management was pursued initially due to advanced age, frailty, and comorbidities, with supportive care after deterioration.","https://schema.org",{"og:url":32,"og:type":74,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":76,"canonical":32},"index,follow",{"doc_id":78,"site_id":7},444053,1790790785,{"code":4,"msg":81,"data":82},"success",[83,87,91,95,100,105,110,114,119,122,126],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":84,"show_sort_weight":85,"slug":86},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":88,"show_sort_weight":89,"slug":90},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":92,"show_sort_weight":93,"slug":94},"Exam",70,"exam",{"id":96,"doc_module":4,"doc_module_name":25,"category_name":97,"show_sort_weight":98,"slug":99},5,"Comic",60,"comic",{"id":101,"doc_module":4,"doc_module_name":25,"category_name":102,"show_sort_weight":103,"slug":104},6,"Technology",50,"technology",{"id":106,"doc_module":4,"doc_module_name":25,"category_name":107,"show_sort_weight":108,"slug":109},7,"Healthcare",40,"healthcare",{"id":111,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":112,"slug":113},8,30,"research-report",{"id":115,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},9,"Religion & Spirituality",20,"religion-spirituality",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":117,"slug":121},"World Cup","world-cup",{"id":123,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":123,"slug":125},10,"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":96,"slug":129},19,"General","general",{"code":4,"msg":81,"data":131},{"doc_id":78,"user_id":132,"nickname":42,"user_avatar":133,"doc_module":4,"category_id":111,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":30,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":101,"language":139,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":12,"update_tm":143,"read_time":144},962085570644,"https://ap-avatar.wpscdn.com/davatar_994ba38a5ba835b3df7d355c54d3ed8d","Review began 11/05/2025  \nReview ended 12/05/2025  \nPublished 12/07/2025  \n© Copyright 2025  \nGhufran et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0. , which permits unrestricted use , distribution , and reproduction in any medium , provided the original author and source are credited.  \nDOI: 10.7759/cureus.98623  \nOpen Access Case Report  \nFatal Spontaneous Rebleeding of Subdural Haematoma Following COVID-19 Infection: A Case Report  \nRimsha Ghufran 1, Sana Aleem 2, Winluck Shayo 2, Abdul Hannan Siddiqui 3  \n1. Internal Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, GBR 2. Acute Medicine, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, GBR 3. Cardiology, University Hospitals of Derby and Burton NHS Foundation Trust, Derby, GBR  \nCorresponding author: Rimsha Ghufran, [r.ghufran@nhs.net](r.ghufran@nhs.net)  \nAbstract  \nCOVID-19 is associated with various neurological complications, including intracranial haemorrhage. However, spontaneous rebleeding of pre-existing subdural haematomas triggered by COVID-19 infection remains exceptionally rare. We report an 88-year-old woman with rheumatoid arthritis who presented with acute-on-chronic subdural haematoma following a fall. Conservative management was pursued, given her advanced age and comorbidities. After seven days of clinical stability, she contracted COVID-19 via PCR screening. Within 24 hours, she experienced catastrophic neurological deterioration (Glasgow Coma Scale declining from 15 to 3) without trauma or anticoagulation. Imaging confirmed worsening subdural haemorrhage with increased midline shift (12 mm) and acute rebleeding. Despite supportive care, she died 10 days later. This case demonstrates a temporal association between COVID-19 infection and fatal subdural haematoma rebleeding, possibly mediated through vascular injury, neuroinflammation, and coagulopathy. Patients with pre-existing intracranial haemorrhage who develop COVID-19 may require heightened neurological surveillance.  \nCategories: Geriatrics, Neurosurgery, Infectious Disease  \nKeywords: cerebrovascular accidents, covid-19, intracranial haemorrhage, spontaneous rebleeding, subdural  \nhematoma  \nIntroduction  \nThe COVID-19 pandemic has revealed the profound neurotropism and vasculopathic potential of SARSCoV-2, with intracranial haemorrhage representing one of the most devastating neurological complications  \n[1] . Cerebrovascular events (both ischemic and haemorrhagic) are the most common neuroradiologic abnormality among COVID-19 patients (27%) [2] . While de novo intracranial haemorrhage in COVID-19 has been increasingly documented, spontaneous rebleeding of pre-existing subdural haematomas triggered by SARS-CoV-2 infection, particularly without trauma or anticoagulation, remains exceptionally rare in the  \nliterature [3,4] .  \nSubdural haematomas typically result from traumatic tearing of bridging veins, with elderly patients at the highest risk due to brain atrophy and vascular fragility [5] . Although recurrence rates following initial  \npresentation range from 5-30% and are traditionally associated with coagulopathy, repeated trauma, or surgical manipulation [6], the interaction between COVID-19 and pre-existing subdural collections remains poorly understood. We present a case of an elderly woman who experienced fatal spontaneous subdural  \nhaematoma rebleeding within 24 hours of COVID-19 diagnosis, occurring without trauma or  \nanticoagulation. This case illustrates the potential for COVID-19 to precipitate catastrophic haemorrhagic  \ncomplications in patients with pre-existing intracranial pathology.  \nCase Presentation  \nAn 88-year-old woman presented to the emergency department following a backwards fall with head trauma that occurred two days before presentation. She reported initially feeling well enough to remain at home, but subsequently developed progressive conf","cbCaiis58tI4CHmz","https://ap.wps.com/l/cbCaiis58tI4CHmz","pdf",1436789,"English","# Introduction\n# Case Presentation\n# Outcome and Discussion","[{\"question\":\"How quickly did the patient deteriorate after COVID-19 diagnosis?\",\"answer\":\"Within 24 hours she experienced catastrophic neurological deterioration, with the Glasgow Coma Scale declining from 15 to 3.\"},{\"question\":\"What imaging findings confirmed acute rebleeding?\",\"answer\":\"Imaging confirmed worsening subdural haemorrhage with increased midline shift (12 mm) and acute rebleeding.\"},{\"question\":\"What treatment approach was chosen for the subdural haematoma?\",\"answer\":\"Conservative management was pursued initially due to advanced age, frailty, and comorbidities, with supportive care after deterioration.\"}]","Fatal Spontaneous Rebleeding of Subdural Haematoma Following COVID-19 Infection - A Case Report | PDF",1790706688,15]