[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-32745":3,"doc-seo-32745":27},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"file_id":15,"file_url":16,"file_type":17,"file_size":18,"view_count":4,"is_deleted":4,"is_public":19,"is_downloadable":19,"audit_status":19,"page_count":20,"language":21,"language_code":22,"table_of_contents":23,"faqs":24,"seo_title":13,"seo_description":14,"update_tm":25,"read_time":26},32745,687197100911,"Himbo","https://ap-avatar.wpscdn.com/avatar/a000239b6f1da00475?_k=1775820430993990792",8,"Research & Report","Extended Characterization of a New Class of Membranes for Blood Purification: The High Cut-Off Membranes","Extended characterization investigates a new class of blood purification membranes, focusing on high cut-off membranes and the difficulties they pose for conventional characterization methods. Dextran sieving curves of high-flux and high cut-off membranes are measured and compared with the glomerular filtration barrier (GFB). Post–blood exposure performance is evaluated for the most permeable synthetic membranes. A new membrane classification approach introduces MWRO to map molecular weight cut-off versus retention onset, enabling differentiation of membrane families and defining MWCO/MWRO regions.","cbCainjKXvyKtBSu","https://ap.wps.com/l/cbCainjKXvyKtBSu","pdf",144725,1,9,"English","en","# Introduction\n## Membrane design and removal mechanisms\n## Membrane classification approach (dextran sieving and MWRO)\n# Methods and characterization\n## Dextran sieving curves and GFB comparison\n## Effect of blood exposure on permeation and selectivity\n# Results and implications\n## Differentiating membrane families and defining MWCO/MWRO regions","[{\"question\":\"What problem do high cut-off membranes create for standard characterization methods?\",\"answer\":\"Their distinct properties make them challenging to characterize using commonly used characterization methods.\"},{\"question\":\"How are dextran sieving curves used in this study?\",\"answer\":\"Dextran sieving curves are measured for representative high-flux and high cut-off blood purification membranes and compared to curves for the glomerular filtration barrier (GFB).\"},{\"question\":\"What new parameter supports the proposed membrane classification method?\",\"answer\":\"The study introduces molecular weight retention onset (MWRO) and uses it with molecular weight cut-off to classify dialysis membrane types via a MWCO versus MWRO landscape.\"}]",1781826462,23,{"code":4,"msg":28,"data":29},"ok",{"site_id":30,"language":22,"slug":31,"title":13,"keywords":32,"description":14,"schema_data":33,"social_meta":84,"head_meta":86,"extra_data":88,"updated_unix":25},105,"extended-characterization-of-a-new-class-of-membranes-for-blood-purification-the-high-cut-off-membranes","",{"@graph":34,"@context":83},[35,52,66],{"@type":36,"itemListElement":37},"BreadcrumbList",[38,42,46,49],{"item":39,"name":40,"@type":41,"position":19},"https://docshare.wps.com","Home","ListItem",{"item":43,"name":44,"@type":41,"position":45},"https://docshare.wps.com/document/","Document",2,{"item":47,"name":12,"@type":41,"position":48},"https://docshare.wps.com/document/research-report/",3,{"item":50,"name":13,"@type":41,"position":51},"https://docshare.wps.com/document/extended-characterization-of-a-new-class-of-membranes-for-blood-purification-the-high-cut-off-membranes/32745/",4,{"url":50,"name":13,"@type":53,"author":54,"headline":13,"publisher":56,"fileFormat":59,"description":14,"dateModified":60,"datePublished":60,"encodingFormat":59,"isAccessibleForFree":61,"interactionStatistic":62},"DigitalDocument",{"name":9,"@type":55},"Person",{"url":39,"name":57,"@type":58},"DocShare","Organization","application/pdf","2026-06-18",true,{"@type":63,"interactionType":64,"userInteractionCount":4},"InteractionCounter",{"@type":65},"ViewAction",{"@type":67,"mainEntity":68},"FAQPage",[69,75,79],{"name":70,"@type":71,"acceptedAnswer":72},"What problem do high cut-off membranes create for standard characterization methods?","Question",{"text":73,"@type":74},"Their distinct properties make them challenging to characterize using commonly used characterization methods.","Answer",{"name":76,"@type":71,"acceptedAnswer":77},"How are dextran sieving curves used in this study?",{"text":78,"@type":74},"Dextran sieving curves are measured for representative high-flux and high cut-off blood purification membranes and compared to curves for the glomerular filtration barrier (GFB).",{"name":80,"@type":71,"acceptedAnswer":81},"What new parameter supports the proposed membrane classification method?",{"text":82,"@type":74},"The study introduces molecular weight retention onset (MWRO) and uses it with molecular weight cut-off to classify dialysis membrane types via a MWCO versus MWRO landscape.","https://schema.org",{"og:url":50,"og:type":85,"og:title":13,"og:site_name":57,"og:description":14},"article",{"robots":87,"canonical":50},"index,follow",{"doc_id":7,"site_id":30}]