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Eighty-five participants completed a modified NEPSY-II Word Generation Task at two time points. In the full sample, the measure did not meet pre-specified reliability and feasibility criteria, though semantic trials were more feasible than phonemic trials. Performance correlated with chronological age and IQ, with no sex effects. 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Eighty-five participants attempted a modified version of the NEPSY-II Word Generation Task at two time points. In the full sample, the measure fell below a priori reliability and feasibility criteria, though feasibility of the semantic trials were higher than feasibility of the phonemic trials. Performance on the measure correlated with chronological age and IQ scores, and no sex-related effects were found. Additional analyses suggested that the semantic verbal fluency trials might be appropriate forchildren with Down syndrome 10 years of age and older. |\n\nPowered by Editorial Manager® and ProduXion Manager® from Aries Systems Corporation  \nManuscript Click here to access/download;Manuscript;Verbal Fluency in   \nDown Syndrome-Revised 09.15.2021.docx  \nVERBAL FLUENCY IN DOWN SYNDROME 1  \nEvaluating Verbal Fluency Outcome Measures in Children with Down Syndrome  \nAbstract  \nThis study evaluates the psychometric properties of a verbal fluency task for potential use as an outcome measure in future clinical trials involving children with Down syndrome. Eightyfive participants attempted a modified version of the NEPSY-II Word Generation Task at two time points. In the full sample, the measure fell below a priori reliability and feasibility criteria, though feasibility of the semantic trials were higher than feasibility of the phonemic trials. Performance on the measure correlated with chronological age and IQ scores, and no sex-related effects were found. Additional analyses suggested that the semantic verbal fluency trials might be appropriate for children with Down syndrome 10 years of age and older.  \nKeywords: Down syndrome, children, adolescents, verbal fluency, outcome measures  \nVERBAL FLUENCY IN DOWN SYNDROME 2  \nEvaluating verbal fluency outcome measures in children with Down syndrome  \nDown syndrome (DS) is one of the most common causes of intellectual disability, and it is typically associated with clinical challenges with executive functioning and language skills (Abbeduto et al., 2007; Fidler et al., 2020; Parker et al., 2010) . Individuals with DS present with challenges in verbal short-term memory and shifting tasks that are further complicated by critical deficits in expressive language (Fabbretti et al., 1997; Fidler, 2005; Fidler et al., 2020) . These impairments in executive control and language highlight a need for effective therapeutic interventions to support cognitive and behavioral outcomes in individuals with DS (Best et al., 2011 ; Daunhauer et al., 2014; Fidler et al., 2020; Naess et al., 2011; Sabat et al., 2020) .  \nMeaningful clinical findings remain limited in pharmacological and behavioral trials pursuing interventions targeting executive function and language in DS (Liogier d'Ardhuy et al., 2015 ; de la Torre et al., 2016; Hart et al., 2017; Hewitt et al., 2005; Kishani et al. 2010; Keeling et al., 2017 ; Wright et al., 2013). These null results may be in part due to a lack of psychometrically evaluated outcome measures appropriate for individuals with DS and other populations with inte","cbCaivDVODSe77jn","https://ap.wps.com/l/cbCaivDVODSe77jn","pdf",999647,41,"English","# Abstract\n# Background and Rationale\n# Verbal Fluency Tasks and Prior Measures","[{\"question\":\"What is the purpose of the study described in this manuscript?\",\"answer\":\"To evaluate psychometric properties of a verbal fluency task as a potential outcome measure for future clinical trials in children with Down syndrome.\"},{\"question\":\"How was the verbal fluency task administered and to whom?\",\"answer\":\"Eighty-five participants attempted a modified version of the NEPSY-II Word Generation Task at two time points.\"},{\"question\":\"What key outcomes were reported regarding reliability, feasibility, and related factors?\",\"answer\":\"In the full sample the measure fell below pre-specified reliability and feasibility criteria, semantic trials were more feasible than phonemic trials, performance correlated with chronological age and IQ, and no sex-related effects were found.\"}]","Evaluating Verbal Fluency Outcome Measures in Children with Down Syndrome | PDF",1790782933,103]