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Coverage spans protein, carbohydrate, nucleic acid, and lipid assemblies; synthetic strategies including directed biological synthesis; molecular biology toolsets; and major spectroscopic, magnetic resonance, diffraction, and microscopy approaches. Designed to connect structure with dynamics using practical experimental concepts and terminology.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/essentials-of-chemical-biology-structure-and-dynamics-of-biological-macromolecules/657150/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/essentials-of-chemical-biology-structure-and-dynamics-of-biological-macromolecules/657150.png","ImageObject",300,407,{"name":92,"@type":93},"Logic","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-10-26",true,{"@type":102,"interactionType":103,"userInteractionCount":19},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What topics does the book cover in the chapter on biological macromolecule structures and lipid assemblies?","Question",{"text":112,"@type":113},"It covers general introduction, protein structure, carbohydrate structure, nucleic acid structure, macromolecular lipid assemblies, and the structural forces that shape biological macromolecules.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How does the book treat chemical and biological synthesis?",{"text":117,"@type":113},"It introduces synthesis in chemical biology and then discusses chemical synthesis of peptides, proteins, nucleic acids, oligosaccharides, and lipids, followed by biological synthesis, including directed biological synthesis of proteins and related syntheses.",{"name":119,"@type":110,"acceptedAnswer":120},"Which experimental techniques are included for structure determination?",{"text":121,"@type":113},"It includes electronic and vibrational spectroscopy, magnetic resonance (including NMR and EPR), and diffraction and microscopy approaches such as X-ray diffraction and neutron diffraction.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},657150,1792974915,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":19,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":129,"read_time":144},1099513958762,"https://ap-avatar.wpscdn.com/avatar/1000023916a998db790?x-image-process=image/resize,m_fixed,w_180,h_180&k=1784791008015729253","Essentials of Chemical Biology  \nStructure and Dynamics of Biological Macromolecules  \nAndrew Miller  \nDepartment of Chemistry, Imperial College London, UK  \nJulian Tanner  \nDepartment of Biochemistry, University of Hong Kong  \nEssentials of Chemical Biology  \nEssentials of Chemical Biology  \nStructure and Dynamics of Biological Macromolecules  \nAndrew Miller  \nDepartment of Chemistry, Imperial College London, UK  \nJulian Tanner  \nDepartment of Biochemistry, University of Hong Kong  \nCopyright  2008 John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester,  \nWest Sussex PO19 8SQ, England  \nTelephone (+44) 1243 779777  \nEmail (for orders and customer service enquiries): [cs-books@wiley.co.uk](cs-books@wiley.co.uk)  \n[Visit our Home Page on](Visit our Home Page on www.wileyeurope)[ www.wileyeurope](Visit our Home Page on www.wileyeurope).com or www.wiley.com  \nAll Rights Reserved. No part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, scanning or otherwise, except under the terms of the Copyright, Designs and Patents Act 1988 or under the terms ofa licence issued by the Copyright Licensing Agency Ltd, 90 Tottenham Court Road, London W1T 4LP, UK, without the permission in writing of the Publisher. Requests to the Publisher should be addressed to the Permissions Department, John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex PO19 8SQ, England, or [emailed to permreq@wiley.co.uk](emailed to permreq@wiley.co.uk), or faxed to (+44) 1243 770620.  \nDesignations used by companies to distinguish their products are often claimed as trademarks. All brand names and product names used in this book are trade names, service marks, trademarks or registered trademarks oftheir respective owners. The Publisher is not associated with any product or vendor mentioned in this book.  \nThis publication is designed to provide accurate and authoritative information in regard to the subject matter covered. It is sold on the understanding that the Publisher is not engaged in rendering professional services. If professional advice or other expert assistance is required, the services ofa competent professional should be sought.  \nOther Wiley Editorial Offices  \nJohn Wiley & Sons Inc., 111 River Street, Hoboken, NJ 07030, USA  \nJossey-Bass, 989 Market Street, San Francisco, CA 94103-1741, USA  \nWiley-VCH Verlag GmbH, Boschstrasse 12, D-69469 Weinheim, Germany  \nJohn Wiley & Sons Australia Ltd, 33 Park Road, Milton, Queensland 4064, Australia  \nJohn Wiley & Sons (Asia) Pte Ltd, 2 Clementi Loop \\#02-01, Jin Xing Distripark, Singapore 129809 John Wiley & Sons Canada Ltd, 6045 Freemont Boulevard, Mississauga, Ontario, Canada L5R 4J3  \nWiley also publishes its books in a variety of electronic formats. Some content that appears in print may not be available in electronic books.  \nLibrary of Congress Cataloging-in-Publication Data  \nMiller, Andrew, 1963–  \nEssentials of chemical biology : structure and dynamics of biological  \nmacromolecules / Andrew Miller and Julian Tanner.  \np. ; cm.  \nISBN 978-0-470-84530-1 (cloth : alk. paper)  \n1. Biochemistry. 2. Molecular biology. 3. Macromolecules.  \nI. Tanner, Julian, 1976– II. Title.  \n[DNLM: 1 . Biochemistry. 2. Chemistry. 3. Macromolecular Substances–chemistry.  \n4. Molecular Biology. QU 4 M6565e 2007]  \nQP514.2.M55 2007  \n612􀀃 .015–dc22  \n2007050369  \nBritish Library Cataloguing in Publication Data  \nA catalogue record for this book is available from the British Library  \nISBN 978-0-470-84530-1 (HB) 978-0-470-84531-8 (PB)  \nTypeset in 10.5/12.5pt Minion by Aptara Inc., New Delhi, India  \nPrinted and bound by Grafos SpA., Barcelona, Spain  \nThis book is printed on acid-free paper responsibly manufactured from sustainable forestry in which at least two trees are planted for each one used for paper production.  \nTo Izumi,  \nwithout whose love, patience, common sense and great encouragem","cbCaisqLoUSiyVJY","https://ap.wps.com/l/cbCaisqLoUSiyVJY","pdf",35474463,592,"English","# Preface\n# Glossary of physical terms\n# The structures of biological macromolecules and lipid assemblies\n## General introduction\n## Protein structure\n## Carbohydrate structure\n## Nucleic acid structure\n## Macromolecular lipid assemblies\n## Structural forces in biological macromolecules\n# Chemical and biological synthesis\n## Introduction to synthesis in chemical biology\n## Chemical synthesis of peptides and proteins\n## Chemical synthesis of nucleic acids\n## Chemical synthesis of oligosaccharides\n## Chemical synthesis of lipids\n## Biological synthesis of biological macromolecules\n## Directed biological synthesis of proteins\n## Biological syntheses of nucleic acids, oligosaccharides and lipids\n# Molecular biology as a toolset for chemical biology\n## Key concepts in molecular biology\n## Tools and techniques in molecular biology\n## Cloning and identification of genes in DNA\n## Integrating cloning and expression\n## Site-directed mutagenesis\n# Electronic and vibrational spectroscopy\n## Electronic and vibrational spectroscopy in chemical biology\n## UV–visible spectroscopy\n## Circular dichroism spectroscopy\n## Vibrational spectroscopy\n## Fluorescence spectroscopy\n## Probing metal centres by absorption spectroscopy\n# Magnetic resonance\n## Magnetic resonance in chemical biology\n## Key principles of NMR\n## Two-dimensional NMR\n## Multi-dimensional NMR\n## Biological macromolecule structural information\n## EPR spectroscopy; key principles\n# Diffraction and microscopy\n## Diffraction and microscopy in chemical biology\n## Key principles of X-ray diffraction\n## Structural information from X-ray diffraction\n## Neutron diffraction","[{\"question\":\"What topics does the book cover in the chapter on biological macromolecule structures and lipid assemblies?\",\"answer\":\"It covers general introduction, protein structure, carbohydrate structure, nucleic acid structure, macromolecular lipid assemblies, and the structural forces that shape biological macromolecules.\"},{\"question\":\"How does the book treat chemical and biological synthesis?\",\"answer\":\"It introduces synthesis in chemical biology and then discusses chemical synthesis of peptides, proteins, nucleic acids, oligosaccharides, and lipids, followed by biological synthesis, including directed biological synthesis of proteins and related syntheses.\"},{\"question\":\"Which experimental techniques are included for structure determination?\",\"answer\":\"It includes electronic and vibrational spectroscopy, magnetic resonance (including NMR and EPR), and diffraction and microscopy approaches such as X-ray diffraction and neutron diffraction.\"}]","Essentials of Chemical Biology - Structure and Dynamics of Biological Macromolecules | PDF",1492]