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Ocular hyperemia, punctate keratitis, and meibomian gland dysfunction were accompanied by systemic mucocutaneous findings, including oral erosive lesions, violaceous skin plaques, onychodystrophy, and dysphagia. Oral and nail biopsies supported systemic erosive lichen planus (ELP) with ocular involvement, while immunofluorescence and infectious/autoimmune serologies were unremarkable. Treatment with azathioprine and short-course oral corticosteroids produced substantial improvement and sustained remission at one year.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/erosive-lichen-planus-with-ocular-involvement-a-case-report/416630/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/erosive-lichen-planus-with-ocular-involvement-a-case-report/416630.png","ImageObject",300,407,{"name":92,"@type":93},"Blitz","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What diagnoses were confirmed in the case report?","Question",{"text":112,"@type":113},"The final diagnosis was lichen planus, specifically systemic erosive lichen planus with ocular involvement supported by biopsy findings.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What ocular signs and systemic symptoms were described?",{"text":117,"@type":113},"Ocular findings included conjunctival hyperemia, punctate keratitis, and meibomian gland dysfunction, alongside oral erosive lesions, violaceous skin plaques, onychodystrophy, and dysphagia.",{"name":119,"@type":110,"acceptedAnswer":120},"How was the condition treated and what was the outcome?",{"text":121,"@type":113},"The patient received azathioprine and a short course of oral corticosteroids, leading to substantial improvement in ocular inflammation, mucocutaneous lesions, and visual acuity, with sustained remission after one year.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},416630,1790726205,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},24464137899374,"https://us-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","e-ISSN 1941-5923  \n© Am J Case Rep, 2025; 26: e950464 DOI: 10. 12659/AJCR.950464  \nReceived: 2025.06.29  \nAccepted: 2025.10.13  \nAvailable online: 2025.11.10  \nPublished: 2025.12.13  \nAuthors’ Contribution: Study Design A  \nData Collection B Statistical Analysis C Data Interpretation D Manuscript Preparation E Literature Search F Funds Collection G  \nABCDEF 1 BCD 1  \nDEF 1 ABCD 1 BDF 1  \nACE 2 ACEG 1 ABCEF 1,2  \nCorresponding Author: Financial support: Conflict of interest:  \nErosive Lichen Planus With Ocular Involvement: A Case Report  \nCaio Henrique Peres Oliani   \nIsabella Passarelli Giabardo Marques  Camyla Lemos Budib   \nNicoli Lopes de Oliveira   \nSamuel Gonçalves de Campos  Roberta Kern Menna Barreto  Marcello Novoa Colombo Barboza  Luiz Antônio de Brito Martins   \nCaio Henrique Peres Oliani, e-mail: [oliani.caio@hotmail.com](oliani.caio@hotmail.com)  \nNone declared  \nNone declared  \n1 Department of Ophthalmology, Hospital Oftalmológico Visão Laser, Santos, SP, Brazil  \n2 Department of Ophthalmology, Santa Casa de Misericórdia de São Paulo, São Paolo, SP, Brazil  \nPatient: Female, 69-year-old  \nFinal Diagnosis: Lichen planus  \nSymptoms: Dysphagia • ocular irritation • oral cavity erosive lesions • visual acuity loss • weight loss Clinical Procedure: —  \nSpecialty: Dermatology • Ophthalmology  \nObjective: Unusual clinical course  \nBackground: Lichen planus, a chronic autoimmune inflammatory disorder, primarily affects the skin and mucous membranes but may occasionally involve the ocular surface. Ocular manifestations are rare, often underrecognized, and potentially similar to other cicatrizing conjunctivitides. If left untreated, ocular lichen planus may lead to substantial morbidity and permanent visual impairment. Early identification and interdisciplinary management are essential to prevent irreversible damage and systemic complications. Awareness of this entity among ophthalmologists and dermatologists is crucial for timely diagnosis.  \nCase Report: A 69-year-old woman developed chronic conjunctivitis and visual decline 3 months after bilateral uncomplicated cataract surgery. Ocular findings included conjunctival hyperemia, punctate keratitis, and meibomian gland dysfunction. Systemic evaluation revealed oral ulcers, violaceous skin plaques, onychodystrophy, and dysphagia. Oral biopsy confirmed lichenoid mucositis, and nail biopsy supported a diagnosis of systemic erosive lichen planus (ELP). Both direct and indirect immunofluorescence findings were negative; hepatitis C and autoimmune serologies were unremarkable. A multidisciplinary team established the diagnosis of ELP with ocular involvement. The patient received azathioprine (100 mg/day) and a short course of oral corticosteroids, which resulted in substantial improvement of ocular inflammation, mucocutaneous lesions, and visual acuity within  \n4 months. Sustained remission was evident after 1 year of follow-up.  \nConclusions: This case underscores the importance of considering ELP in patients who present with chronic ocular surface inflammation and concomitant mucocutaneous lesions. Ophthalmologists play a key role in recognizing systemic inflammatory disorders and coordinating interdisciplinary care. Prompt diagnosis, long-term follow-up, and systemic immunosuppressive therapy are vital to prevent scarring and permanent sequelae.  \nKeywords: Autoimmune Diseases • Conjunctival Diseases • Eye Manifestations • Immunosuppressive Agents • Interdisciplinary Communication • Lichen Planus  \nFull-text PDF: [https://www.amjcaserep.com/abstract/index/idArt/950464](https://www.amjcaserep.com/abstract/index/idArt/950464)  \n1629  —  3  16  \nPublisher’s note: All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or e","cbCaii2GKIEf7GdS","https://ap.wps.com/l/cbCaii2GKIEf7GdS","pdf",881252,"English","# Introduction\n# Case Report\n## Ocular findings and systemic evaluation\n## Treatment and follow-up\n# Conclusions","[{\"question\":\"What diagnoses were confirmed in the case report?\",\"answer\":\"The final diagnosis was lichen planus, specifically systemic erosive lichen planus with ocular involvement supported by biopsy findings.\"},{\"question\":\"What ocular signs and systemic symptoms were described?\",\"answer\":\"Ocular findings included conjunctival hyperemia, punctate keratitis, and meibomian gland dysfunction, alongside oral erosive lesions, violaceous skin plaques, onychodystrophy, and dysphagia.\"},{\"question\":\"How was the condition treated and what was the outcome?\",\"answer\":\"The patient received azathioprine and a short course of oral corticosteroids, leading to substantial improvement in ocular inflammation, mucocutaneous lesions, and visual acuity, with sustained remission after one year.\"}]","Erosive Lichen Planus With Ocular Involvement - A Case Report | PDF",1790606108,13]