[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-362489-105":59,"doc-detail-362489-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","epidermal-inclusion-cyst-of-the-breast-a-case-report","Epidermal inclusion cyst of the breast - A case report","","Epidermal inclusion cysts are nonmalignant squamous epithelial proliferations within the dermis, with uncommon occurrence in the breast and significant diagnostic difficulty. This case report details multimodal imaging findings and differential diagnosis of a rare breast epidermal inclusion cyst capable of mimicking malignant neoplasms. A 38-year-old woman presented with a progressively enlarging right breast nodule. Clinical exam showed a firm upper inner quadrant mass. Ultrasound showed a heterogeneous solid nodule, mammography revealed a hyperdense BI-RADS 4 mass, and MRI demonstrated a BI-RADS 4 ring-enhancing lesion with restricted diffusion. Ultrasound-guided core biopsy confirmed the diagnosis histologically, emphasizing inclusion in differential to prevent unnecessary invasive procedures.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/epidermal-inclusion-cyst-of-the-breast-a-case-report/362489/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/epidermal-inclusion-cyst-of-the-breast-a-case-report/362489.png","ImageObject",300,407,{"name":92,"@type":93},"Kyle","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-23","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why are epidermal inclusion cysts difficult to diagnose in the breast?","Question",{"text":112,"@type":113},"They are benign squamous epithelial proliferations that are rare in the breast and can closely mimic malignant tumors on imaging, especially when diffusion restriction is present.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What imaging findings were reported for the presented breast lesion?",{"text":117,"@type":113},"Ultrasound showed a heterogeneous solid nodule, mammography found a sizable well-defined hyperdense BI-RADS 4 mass, and MRI demonstrated a well-defined T2/STIR hyperintense lesion with ring-like internal enhancement and restricted diffusion, classified as BI-RADS 4.",{"name":119,"@type":110,"acceptedAnswer":120},"How was the diagnosis confirmed in this case report?",{"text":121,"@type":113},"An ultrasound-guided core biopsy was performed, and histological analysis confirmed an epidermal inclusion cyst.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},362489,1790637680,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":34,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},3985741905716,"https://ap-avatar.wpscdn.com/davatar_994ba38a5ba835b3df7d355c54d3ed8d","Radiology Ca s e Reports 21 (2026) 1919 – 1925  \nAvailable online [at](at www.sciencedirect.com)[ www.sciencedirect.com](at www.sciencedirect.com)  \njournal [homepage:](homepage: www.elsevier.com/locate/radcr)[ www.elsevier.com/locate/radcr](homepage: www.elsevier.com/locate/radcr)  \n| Case Report\u003Cbr>Epidermal inclusion cyst of the breast: A case report ✩,✩✩\u003Cbr>Paula Daniela Vásquez-Rentería, MDa,b,c,d,e, Diego D’Angelo Claure-Robles, MDa,b,f, Deborah Amanda Grados-Godenzi, MDa,b,f, Sebastian Coronel-Arias, MDa,b,f,∗\u003Cbr>a Hospital Nacional Dos de Mayo, Av. Miguel Grau 1549, Cercado de Lima, Lima, 15003, Perú b Sociedad Peruana de Radiología, Av. José Pardo 138 Of. 603, Lima, 15074, Perú c European Society of Breast Imaging (EUSOBI), Am Gestade 1, Vienna, 1010, Austria d Society Breast Imaging (SBI), 6800 Paragon Place, Suite 640, Richmond, VA 23230, USA\u003Cbr>e Sociedad Iberoamericana de Imágenes Mamarias (SIBIM), Las Condes, Región Metropolitana, Santiago, 7561155, Chile\u003Cbr>f Universidad Nacional Mayor de San Marcos, Av. Miguel Grau 755, Cercado de Lima, Lima, 15001, Perú |  |  |\n| --- | --- | --- |\n| a r t i c l e i n f o |  | a b s t r a c t |\n| Article history:\u003Cbr>Received 16 October 2025 Revised 15 January 2026 Accepted 18 January 2026 |  | Epidermal inclusion cysts are nonmalignant proliferations ofsquamous epithelium situated within the dermis. Their presence in the breast is uncommon and presents considerable diagnostic difficulty. This case report aims to elucidate the multimodal imaging findings and differential diagnosis of a rare breast epidermal inclusion cyst, highlighting its capacity to mimic malignant neoplasms. We present a case of a 38-year-old female with a palpable right breast nodule that had progressively increased over a period of 15 years. A clinical examination identified a firm mass in the upper inner quadrant of the right breast. Ultrasound revealed a heterogeneous solid nodule, whilst mammography detected a sizable, well-defined hyperdense mass (BI-RADS 4) . Magnetic resonance imaging demonstrated a well-defined nodule with T2/STIR hyperintensity, characterized by a ring-like internal enhancement pattern and restricted diffusion, classified as BI-RADS 4. An ultrasound-guided core biopsy was performed, and histological analysis confirmed the diagnosis of an epidermal inclusion cyst. This case underscores the importance of considering epidermal inclusion cysts in the differential diagnosis of breast cancers with imaging features to avoid unnecessary invasive interventions.\u003Cbr>© 2026 The Authors. Published by Elsevier Inc. on behalf of University of Washington.\u003Cbr>This is an open access article under the CC BY-NC-ND license\u003Cbr>([http://creativecommons.org/licenses/by-nc-nd/4.0/](http://creativecommons.org/licenses/by-nc-nd/4.0/)) |\n| Keywords: Epidermal cyst Breast diseases Diagnostic imaging |  |  |\n\n✩ Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.  \n✩✩ Acknowledgments: Special thanks to Gustavo Adolfo Cerrillo Sanchez and Milvia Gloria Garrido Millan, Anatomical Pathologists, MD at Hospital Nacional Dos de Mayo, Lima, Peru, for their expert review of the histopathological findings and for providing the slides used in this report. The author(s) received no financial support for the research, authorship, and/or publication of this article.  \n∗ Corresponding author.  \nE-mail address: [scoronela1@gmail.com](scoronela1@gmail.com) (S. Coronel-Arias).  \n[https://doi.org/10.1016/j.radcr.2026.01.065](https://doi.org/10.1016/j.radcr.2026.01.065)  \n1930-0433/© 2026 The Authors. Published by Elsevier Inc. on behalf of University of Washington. This is an open access article under the CC BY-NC-ND license ([http://creativecommons.org/licenses/by-nc-nd/4.0/](http://creativecommons.org/licenses/by-nc-nd/4.0/))  \nIntroduction  \nEpidermal inclusion cysts are benign lesions form","cbCaisoDMgKw0gLF","https://ap.wps.com/l/cbCaisoDMgKw0gLF","pdf",2361083,"English","# Article history\n## Case report","[{\"question\":\"Why are epidermal inclusion cysts difficult to diagnose in the breast?\",\"answer\":\"They are benign squamous epithelial proliferations that are rare in the breast and can closely mimic malignant tumors on imaging, especially when diffusion restriction is present.\"},{\"question\":\"What imaging findings were reported for the presented breast lesion?\",\"answer\":\"Ultrasound showed a heterogeneous solid nodule, mammography found a sizable well-defined hyperdense BI-RADS 4 mass, and MRI demonstrated a well-defined T2/STIR hyperintense lesion with ring-like internal enhancement and restricted diffusion, classified as BI-RADS 4.\"},{\"question\":\"How was the diagnosis confirmed in this case report?\",\"answer\":\"An ultrasound-guided core biopsy was performed, and histological analysis confirmed an epidermal inclusion cyst.\"}]","Epidermal inclusion cyst of the breast - A case report | PDF",1790147946,18]