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Analyses used 1,001 participants from the DORMIR study, defining insomnia by frequent self-reported sleep difficulty or medication use and measuring overnight sleep duration by actigraphy. ISSD and LS prevalence varied by race/ethnicity, and several comorbidities differed between phenotypes despite broadly similar dementia status.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/epidemiology-of-high-risk-sleep-phenotypesin-a-diverse-cohort-of-older-adults/428182/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/epidemiology-of-high-risk-sleep-phenotypesin-a-diverse-cohort-of-older-adults/428182.png","ImageObject",300,407,{"name":92,"@type":93},"Adam","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-20","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":24},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What are the high-risk sleep phenotypes examined in the study?","Question",{"text":112,"@type":113},"The study examines insomnia with objectively short sleep duration (ISSD) and insomnia with objectively long sleep duration (LS). It also includes normal sleep (NS) as a comparison phenotype.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was insomnia defined and sleep duration measured?",{"text":117,"@type":113},"Insomnia was defined by self-reported sleep problems or sleep medication use occurring at least 3 times per week. Objective overnight sleep duration was assessed using actigraphy averaged over about 5.9 days.",{"name":119,"@type":110,"acceptedAnswer":120},"Do the prevalence and comorbidities differ across race/ethnicity groups?",{"text":121,"@type":113},"Yes. ISSD and LS prevalence differed by race/ethnicity (e.g., higher ISSD among Blacks and higher LS among Whites). Depression was higher in ISSD and LS than in NS across groups, while anxiety patterns varied by group; physical impairment was higher in LS than NS across groups.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},428182,1790794593,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":24,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":8,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":81},1374404737137,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","558 Innovation in Aging, 2025, Vol. 9, No. S2  \nAbstract citation ID: igaf122.1914  \nEPIDEMIOLOGY OF HIGH-RISK SLEEP PHENOTYPESIN A DIVERSE COHORT OF OLDER ADULTS  \nBrienne Miner1, Jarett Talarczyk1, Clemence Cavailles2, Carrie Peltz3, and Kristine Yaffe2, 1. Yale University, New Haven, Connecticut, United States, 2. University of California, San Francisco, San Francisco, California, United States,  \n3. Northern California Institute for Research and Education, San Francisco, California, United States  \nBackground: Insomnia with objective short sleep duration (ISSD) and objective long sleep duration (LS) are high-risk sleep phenotypes that have not been examined in a diverse group of older adults. Methods: We studied 1001 adults in the DORMIR study (average age 64.4[8.6] years, 65.7% female; 28.4% Black, 31.6% Hispanic, 40.1% non-Hispanic White) . Insomnia was defined as self-reporting any of the following >=3 times/week: trouble getting to sleep within 30min, waking in the middle of the night/early morning or taking sleep medication. Objective overnight sleep duration was assessed by actigraphy (averagedover 5.9[0.9] days). We examined ISSD (insomnia and sleep duration\u003C 6h), LS (sleep duration>8h), and normal sleep (NS; no insomnia and sleep duration=6-8h) . Using ANOVA F-tests or chi-square, we assessed phenotype prevalence overall and according to race/ethnicity, and also examined, within each race/ethnicity group, whether comorbidities (e.g., depression, anxiety, dementia status, physical impairment [Short Physical Performance Battery\u003C 10]) differed among phenotypes. Results: ISSD prevalence was 8.1% overall and was higher among Blacks (13.4%; p \u003C 0.001) . LS prevalence was 22.1% overall and was higher among Whites (27.2%; p \u003C 0.001). Compared to NS, depression was higher in ISSD and LS across all groups. Anxiety was higher in Hispanics and Whites with ISSD and LS compared with NS. Across all groups, physical impairment was significantly higher in LS compared with NS. Dementia status was not different across phenotypes. Conclusion: The prevalence of high-risk sleep phenotypes differs across race/ethnicity groups, while comorbidities associated with phenotypes were similar. Future work should examine the association of phenotypes with adverse outcomes.","cbCaieg2F6Fhzz8m","https://ap.wps.com/l/cbCaieg2F6Fhzz8m","pdf",48441,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusion","[{\"question\":\"What are the high-risk sleep phenotypes examined in the study?\",\"answer\":\"The study examines insomnia with objectively short sleep duration (ISSD) and insomnia with objectively long sleep duration (LS). It also includes normal sleep (NS) as a comparison phenotype.\"},{\"question\":\"How was insomnia defined and sleep duration measured?\",\"answer\":\"Insomnia was defined by self-reported sleep problems or sleep medication use occurring at least 3 times per week. Objective overnight sleep duration was assessed using actigraphy averaged over about 5.9 days.\"},{\"question\":\"Do the prevalence and comorbidities differ across race/ethnicity groups?\",\"answer\":\"Yes. ISSD and LS prevalence differed by race/ethnicity (e.g., higher ISSD among Blacks and higher LS among Whites). Depression was higher in ISSD and LS than in NS across groups, while anxiety patterns varied by group; physical impairment was higher in LS than NS across groups.\"}]","EPIDEMIOLOGY OF HIGH-RISK SLEEP PHENOTYPESIN A DIVERSE COHORT OF OLDER ADULTS | PDF",1790646019]