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A single-center retrospective cohort included patients treated between 2012 and 2017 with Doppler ultrasound surveillance every 3 months during the first year. In 248 patients (287 limbs), overall technical success reached 87%, with primary patency at 41.5% at 1 year and amputation-free outcomes of 80.8% at 1 year and 67.7% at 3 years. 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Follow-up included Doppler ultrasound conduction every 3 months during the first year unless CLTI symptoms appeared.",{"name":120,"@type":111,"acceptedAnswer":121},"What were the main results regarding technical success and limb outcomes?",{"text":122,"@type":114},"A total of 248 patients (287 limbs) were treated, with overall technical success of 87%. Primary patency was 41.5% at 1 year, and freedom from amputation was 80.8% at 1 year and 67.7% at 3 years.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},265950,1789402759,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":29,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":130,"read_time":144},16904993612988,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Copyright© Author(s) -[Available online at dirjournal.org.](Available online at dirjournal.org. ORIGINAL)[ ORIGINAL](Available online at dirjournal.org. ORIGINAL) ARTICLE  \nContent of this journal is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.  \nEndovascular recanalization of infra-popliteal TASC C and TASC D lesions in patients with critical limb-threatening ischemia: a singlecenter experience  \n Mehmet Koray Akkan1  \n Ali CanYalçın2  \nTolga Zeydanlı3  Fatih Öncü1  \n Erhan Turgut Ilgıt1  \n Ahmet Baran Önal1  Mustafa Hakan Zor4  \n Abdullah Özer4  \n1Gazi University Faculty of Medicine, Department of Radiology, Ankara, Turkey  \n2Konya City Hospital, Clinic of Radiology, Konya, Turkey  \n3Başkent University Ankara Hospital, Department of Radiology, Ankara, Turkey  \n4Gazi University Faculty of Medicine, Department of Cardiovascular Surgery, Ankara, Turkey  \nPURPOSE  \nThe present study aims to (1) assess the technical success and limb salvage rates of endovascular therapy in patients with critical limb-threatening ischemia (CLTI) and infra-popliteal Trans-Atlantic Inter-Society Consensus (TASC) C/D lesions according to the updated 2015 TASC II classification and (2) to present our institutional experience.  \nMETHODS  \nA single-center retrospective study was conducted on patients with TASC C/D CLTI who underwent endovascular treatment between 2012 and 2017. The follow-up protocol consisted of Doppler ultrasound conduction every 3 months for the first year unless patients showed symptoms of CLTI. Patients with at least 1 year of follow-up data were included in the study, and if applicable their 3-year results were evaluated in terms of primary patency, absence of amputation, amputation-free survival, and overall survival.  \nRESULTS  \nA total of 248 patients and 287 limbs (238 TASC D lesions and 49 TASC C lesions) were treated via infra-popliteal percutaneous transluminal angioplasty. The overall technical success was 87%, the primary patency rate was 41.5% in the first year, and the freedom from amputation rates were 80.8% in 1 year and 67.7% in 3 years.  \nCONCLUSION  \nIn patients with infra-popliteal arterial occlusive diseases, endovascular treatment methods demonstrate a high rate of technical success and favorable outcomes in limb preservation.  \nKEYWORDS  \nPercutaneous angioplasty, infra-popliteal arteries, critical limb ischemia, TASC  \nCorresponding author: Tolga Zeydanlı  \nE-mail: [tz.tolga@gmail.com](tz.tolga@gmail.com)  \nReceived 28 October 2023; revision requested 11 November 2023; accepted 11 January 2024.  \nEpub: 31.01.2024  \nPublication date: 30.12.2024  \nDOI: 10.4274/dir.2024.232524  \nInfra-popliteal arterial disease constitutes a substantial contributor to critical limb-threaten  \ning ischemia (CLTI); it is also closely associated with elevated rates of limb amputation and  \nmortality. CLTI is marked by (1) a presence of persistent ischemic pain at rest or (2) tissue loss, typically occurring in the distal parts of the lower extremities.1-4 Surgical revascularization of CLTI for limb salvage is a known traditional treatment option; however, an increasing number of centers are treating patients with CLTI via endovascular procedures as the first approach. With the development of small-size stents, low profile balloon catheters, hydrophilic guidewires, support catheters, recanalization devices, and vasodilators, the endovascular approach for infra-popliteal arterial occlusive disease is becoming increasingly common.5-7 Surgical methods carry an elevated risk of systemic and local complications attributable to the presence of multiple comorbidities.8  \nYou may cite this article as: Akkan MK, Yalçın AC, Zeydanlı T, et al. Endovascular recanalization of infra-popliteal TASC C and TASC D lesions in patients with  \ncritical limb-threatening ischemia: a single-center experience. Diagn Interv Radiol. 2025;31(1):39-44 .  \n39  \nCLTI is defined as a Rutherford 4, 5 and 6 disease (ischemic ","cbCaibCnDju4gZzq","https://ap.wps.com/l/cbCaibCnDju4gZzq","pdf",528138,"English","# Purpose\n## Technical success and limb salvage assessment\n# Methods\n## Study design and follow-up\n# Results\n## Patient and limb counts and outcome rates\n# Conclusion\n## Overall clinical implications","[{\"question\":\"What is the purpose of this study on CLTI with infra-popliteal TASC C/D lesions?\",\"answer\":\"To assess technical success and limb salvage rates of endovascular therapy for CLTI with infra-popliteal TASC C/D lesions using the updated 2015 TASC II classification, and to report the authors’ institutional experience.\"},{\"question\":\"How was the study conducted and what follow-up was performed?\",\"answer\":\"It was a single-center retrospective study of patients with TASC C/D CLTI treated endovascularly between 2012 and 2017. Follow-up included Doppler ultrasound conduction every 3 months during the first year unless CLTI symptoms appeared.\"},{\"question\":\"What were the main results regarding technical success and limb outcomes?\",\"answer\":\"A total of 248 patients (287 limbs) were treated, with overall technical success of 87%. Primary patency was 41.5% at 1 year, and freedom from amputation was 80.8% at 1 year and 67.7% at 3 years.\"}]","Endovascular recanalization of infra-popliteal TASC C and TASC D lesions in patients with critical limb-threatening ischemia - a single-center experience | PDF",15]