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Gastric variceal bleeding accounts for about 20% of variceal bleeding and carries high morbidity and mortality. Traditional endoscopic injection using thrombosis-inducing agents such as glue can cause systemic embolization, endoscope injury, and recurrent bleeding. EUS-guided coil embolization improves visualization, efficacy, and safety compared with conventional glue injection, though standardization remains challenging.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/endoscopic-ultrasound-guided-coil-embolization-for-gastric-varices-a-promising-alternative-to-traditional-therapies/406393/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/endoscopic-ultrasound-guided-coil-embolization-for-gastric-varices-a-promising-alternative-to-traditional-therapies/406393.png","ImageObject",300,407,{"name":92,"@type":93},"Đào","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-03","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",14,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What is EUS-guided coil embolization used for in this review?","Question",{"text":113,"@type":114},"It is presented as an endoscopic ultrasound-guided vascular intervention for managing gastric varices and gastric variceal hemorrhage.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How does EUS-guided coil embolization compare with traditional glue injection?",{"text":118,"@type":114},"Compared with conventional glue injection, EUS-guided embolization is associated with improved visualization, higher efficacy, and a better safety profile.",{"name":120,"@type":111,"acceptedAnswer":121},"Why is standardization of EUS-guided embolization considered difficult?",{"text":122,"@type":114},"The review states that, despite increasing adoption, the standardization of EUS-guided embolization remains a challenge and high-quality studies are needed to standardize the technique and define its role in clinical practice.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},406393,1790813170,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":145,"read_time":41,"preview_page_count":4},1374402968488,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","| W | J | G | E | World Journal of\u003Cbr>Gastrointestinal Endoscopy |\n| --- | --- | --- | --- | --- |\n\nSubmit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Gastrointest Endosc 2025 December 16; 17(12): 110168  \nDOI: 10.4253/wjge.v17.i12.110168 ISSN 1948-5190 (online)  \nMINIREVIEWS  \nEndoscopic ultrasound-guided coil embolization for gastric varices: A promising alternative to traditional therapies  \nAnthony El Dada, Mandy El Khoury, Peter Stephan, Fredy Nehme  \nSpecialty type: Gastroenterology and hepatology  \nProvenance and peer review:  \nInvited article; Externally peer reviewed.  \nPeer-review model: Single blind  \nPeer-review report’s classification Scientific Quality: Grade B  \nNovelty: Grade B  \nCreativity or Innovation: Grade B  \nScientific Significance: Grade B  \nP-Reviewer: Türkmen U, Associate Professor, Türkiye  \nReceived: June 3, 2025  \nRevised: June 24, 2025  \nAccepted: October 22, 2025  \nPublished online: December 16, 2025  \nProcessing time: 200 Days and 0.3 Hours  \nAnthony El Dada, Mandy El Khoury, Department of Medicine, University of Balamand, Beirut 100, Beyrouth, Lebanon  \nPeter Stephan, Department of Medicine, Saint George University of Beirut, Beirut 100, Beyrouth, Lebanon  \nFredy Nehme, Department of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN 46202, United States  \nCo-first authors: Anthony El Dada and Mandy El Khoury.  \nCorresponding author: Fredy Nehme, MD, Assistant Professor, Department of Gastroenterology and Hepatology, Indiana University School of Medicine, 340 W 10th Street, Indianapolis, IN 46202, [United States.](United States. nehme.fredy@gmail.com)[ nehme.fredy@gmail.com](United States. nehme.fredy@gmail.com)  \nAbstract  \nEndoscopic ultrasound (EUS) guided vascular interventions have expanded the reach of therapeutic endoscopy to include vascular pathology previously inaccessible by endoscopists. Gastric variceal bleeding comprises 20% of all variceal bleeding and is associated with high morbidity and mortality. Historically, endoscopic injection of thrombosis-inducing agents such as glue has been used. However, glue injection carries potential risks including systemic embolization, damage to the endoscope, and recurrent bleeding. The introduction of hemostatic coils has revolutionized the endoscopic approach, with EUS-guided coil embolization emerging as an effective and safe modality for the management of gastric varices (GVs) . When compared with conventional glue injection, EUSguided embolization is associated with improved visualization, higher efficacy, and better safety profile. Despite its expanding adoption, the standardization of EUS guided embolization remains a challenge. High-quality studies are needed to standardize this promising technique and define its role in clinical practice. In this review, we will discuss the indications, efficacy, techniques, and various approaches for EUS-guided embolization of GVs.  \nKey Words: Gastric variceal hemorrhage; Endoscopic ultrasound; Therapeutic endoscopy; Coil embolization; Cyanoacrylate; Gastrointestinal bleeding  \n©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.  \n WJGE  [https://www.wjgnet.com](https://www.wjgnet.com) 1 December 16, 2025  Volume 17  Issue 12   \nEl Dada A et al. EUS-guided interventions for GVs  \nCore Tip: Endoscopic ultrasound (EUS)-guided vascular interventions have changed the treatment landscape of gastric varices, providing a safer, more effective alternative to conventional glue injection. EUS-guided coil embolization improves visualization, provides higher efficacy and is associated with fewer complications including systemic embolization andrecurrent bleeding. Nevertheless, the procedure remains difficult to standardize, and high-quality data is lacking to inform and optimize the treatment approach. This review will discuss the indications, techniques and emerging role of EUS-guided embolization i","cbCaivNIRIcSfp8O","https://ap.wps.com/l/cbCaivNIRIcSfp8O","pdf",6872997,12,"English","# Minireviews\n## Endoscopic ultrasound-guided coil embolization for gastric varices\n## Abstract\n## Core Tip\n## Introduction","[{\"question\":\"What is EUS-guided coil embolization used for in this review?\",\"answer\":\"It is presented as an endoscopic ultrasound-guided vascular intervention for managing gastric varices and gastric variceal hemorrhage.\"},{\"question\":\"How does EUS-guided coil embolization compare with traditional glue injection?\",\"answer\":\"Compared with conventional glue injection, EUS-guided embolization is associated with improved visualization, higher efficacy, and a better safety profile.\"},{\"question\":\"Why is standardization of EUS-guided embolization considered difficult?\",\"answer\":\"The review states that, despite increasing adoption, the standardization of EUS-guided embolization remains a challenge and high-quality studies are needed to standardize the technique and define its role in clinical practice.\"}]","Endoscopic ultrasound-guided coil embolization for gastric varices - A promising alternative to traditional therapies | PDF",1790565373]