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Final pathology confirmed EGC association in 59.6%.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/endoscopic-features-and-treatments-of-gastric-cystica-profunda-original-article/337593/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/endoscopic-features-and-treatments-of-gastric-cystica-profunda-original-article/337593.png","ImageObject",300,407,{"name":42,"@type":43},"Lucas Martin","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-29","2026-09-21",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",12,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What is gastric cystica profunda (GCP) and why is it clinically important?","Question",{"text":63,"@type":64},"GCP is a rare gastric lesion characterized by cystic dilation of gastric glands within the mucosal and/or submucosal layers. It can be linked to, or progress into, early gastric cancer (EGC), making diagnosis and management important.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"How was the study conducted and what was the main treatment evaluated?",{"text":68,"@type":64},"The study was a retrospective analysis of 104 patients with GCP who underwent endoscopic resection. Follow-up was performed to assess local recurrence.",{"name":70,"@type":61,"acceptedAnswer":71},"What endoscopic and pathological findings were most notable in the results?",{"text":72,"@type":64},"GCP most often showed intraluminal growth and regular appearance, and a majority had ulcerative mucosa. The leading endoscopic feature was the mucosal lesion type, and final pathology confirmed EGC association in 59.6% of cases.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},337593,1790245066,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,110,115,120,123,127],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":107,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":108,"slug":109},7,40,"healthcare",{"id":111,"doc_module":4,"doc_module_name":25,"category_name":112,"show_sort_weight":113,"slug":114},8,"Research & Report",30,"research-report",{"id":116,"doc_module":4,"doc_module_name":25,"category_name":117,"show_sort_weight":118,"slug":119},9,"Religion & Spirituality",20,"religion-spirituality",{"id":118,"doc_module":4,"doc_module_name":25,"category_name":121,"show_sort_weight":118,"slug":122},"World Cup","world-cup",{"id":124,"doc_module":4,"doc_module_name":25,"category_name":125,"show_sort_weight":124,"slug":126},10,"Lifestyle","lifestyle",{"id":128,"doc_module":4,"doc_module_name":25,"category_name":129,"show_sort_weight":97,"slug":130},19,"General","general",{"code":4,"msg":82,"data":132},{"doc_id":79,"user_id":133,"nickname":42,"user_avatar":134,"doc_module":4,"category_id":107,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":140,"language":141,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":12,"update_tm":145,"read_time":146},8796095360427,"https://ap-avatar.wpscdn.com/davatar_994ba38a5ba835b3df7d355c54d3ed8d","| W | J | G | World Journal of\u003Cbr>Gastroenterology |\n| --- | --- | --- | --- |\n\nSubmit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Gastroenterol 2024 February 21; 30(7): 673-684  \nDOI: 10.3748/wjg.v30.i7.673 ISSN 1007-9327 (print) ISSN 2219-2840 (online)  \nORIGINAL ARTICLE  \nRetrospective Study  \nEndoscopic features and treatments of gastric cystica profunda  \nZi-Han Geng, Yan Zhu, Pei-Yao Fu, Yi-Fan Qu, Wei-Feng Chen, Xia Yang, Ping-Hong Zhou, Quan-Lin Li  \nSpecialty type: Gastroenterology and hepatology  \nProvenance and peer review:  \nUnsolicited article; Externally peer reviewed.  \nPeer-review model: Single blind  \nPeer-review report’s scientific quality classification  \nGrade A (Excellent): 0  \nGrade B (Very good): 0  \nGrade C (Good): C  \nGrade D (Fair): 0  \nGrade E (Poor): 0  \nP-Reviewer: Shahidi N, Canada  \nReceived: December 11, 2023  \nPeer-review started: December 11, 2023  \nFirst decision: December 19, 2023  \nRevised: December 25, 2023  \nAccepted: January 22, 2024  \nArticle in press: January 22, 2024  \nPublished online: February 21, 2024  \nZi-Han Geng, Yan Zhu, Pei-Yao Fu, Yi-Fan Qu, Wei-Feng Chen, Xia Yang, Ping-Hong Zhou, QuanLin Li, Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, Shanghai 200032, China  \nCorresponding author: Ping-Hong Zhou, FASGE, MD, Chief Physician, Doctor, Surgeon, Teacher, Endoscopy Center and Endoscopy Research Institute, Zhongshan Hospital, Fudan University, No. 180 Fenglin Road, Xuhui District, Shanghai 200032, China.  \n[zhou.pinghong@zs-hospital.sh.cn](zhou.pinghong@zs-hospital.sh.cn)  \nAbstract  \nBACKGROUND  \nGastric cystica profunda (GCP) represents a rare condition characterized by cystic dilation of gastric glands within the mucosal and/or submucosal layers. GCP is often linked to, or may progress into, early gastric cancer (EGC) .  \nAIM  \nTo provide a comprehensive evaluation of the endoscopic features of GCP while assessing the efficacy of endoscopic treatment, thereby offering guidance for diagnosis and treatment.  \nMETHODS  \nThis retrospective study involved 104 patients with GCP who underwent endoscopic resection. Alongside demographic and clinical data, regular patient followups were conducted to assess local recurrence.  \nRESULTS  \nAmong the 104 patients diagnosed with GCP who underwent endoscopic resection, 12.5% had a history of previous gastric procedures. The primary site predominantly affected was the cardia (38.5%, n = 40) . GCP commonly exhibited intraluminal growth (99%), regular presentation (74.0%), and ulcerative mucosa (61.5%). The leading endoscopic feature was the mucosal lesion type (59.6%, n = 62) . The average maximum diameter was 20.9 ± 15.3 mm, with mucosal involvement in 60.6%(n = 63) . Procedures lasted 73.9 ± 57.5 min, achieving complete resection in 91.3%(n = 95) . Recurrence (4.8%) was managed via either surgical intervention (n = 1) or through endoscopic resection (n = 4) . Final pathology confirmed that 59.6% of GCP cases were associated with EGC. Univariate analysis indicated that elderly males were more susceptible to GCP associated with EGC. Conversely, multivariate analysis identified lesion morphology and endoscopic features as significant risk factors. Survival analysis demonstrated no statistically significant difference in recurrence between GCP  \n WJG  [https://www.wjgnet.com](https://www.wjgnet.com) 673 February 21, 2024  Volume 30  Issue 7   \nGeng ZH et al. Endoscopic features and treatments of GCP with and without EGC (P = 0.72) .  \nCONCLUSION  \nThe findings suggested that endoscopic resection might serve as an effective and minimally invasive treatment for GCP with or without EGC.  \nKey Words: Gastric cystica profunda; Early gastric cancer; Endoscopic features; Endoscopic resection; Endoscopy  \n©The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.  \nCore Tip: Gastric cystica profunda (GCP) associated early gastric cancer (EGC) w","cbCaidncDwgfyUXw","https://ap.wps.com/l/cbCaidncDwgfyUXw","pdf",4912659,13,"English","# Abstract\n## Background\n## Aim\n## Methods\n## Results\n## Conclusion\n# Introduction","[{\"question\":\"What is gastric cystica profunda (GCP) and why is it clinically important?\",\"answer\":\"GCP is a rare gastric lesion characterized by cystic dilation of gastric glands within the mucosal and/or submucosal layers. It can be linked to, or progress into, early gastric cancer (EGC), making diagnosis and management important.\"},{\"question\":\"How was the study conducted and what was the main treatment evaluated?\",\"answer\":\"The study was a retrospective analysis of 104 patients with GCP who underwent endoscopic resection. Follow-up was performed to assess local recurrence.\"},{\"question\":\"What endoscopic and pathological findings were most notable in the results?\",\"answer\":\"GCP most often showed intraluminal growth and regular appearance, and a majority had ulcerative mucosa. The leading endoscopic feature was the mucosal lesion type, and final pathology confirmed EGC association in 59.6% of cases.\"}]","Endoscopic features and treatments of gastric cystica profunda - Original Article | PDF",1790019710,33]