[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-426623-105":59,"doc-detail-426623-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","effects-of-social-isolation-on-mortality-in-older-adults-do-age-and-gender-matter","Effects of Social Isolation on Mortality in Older Adults: Do Age and Gender Matter?","","Social isolation is a recognized risk factor for adverse health outcomes, but its effect size on mortality and whether it differs by gender remain uncertain. This study tests whether social isolation predicts all-cause mortality and whether the association varies for men and women. Data come from the National Health and Aging Trends Study (NHATS) and include 7,186 baseline community-living respondents, with 28.5% weighted mortality by 2023.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/effects-of-social-isolation-on-mortality-in-older-adults-do-age-and-gender-matter/426623/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/effects-of-social-isolation-on-mortality-in-older-adults-do-age-and-gender-matter/426623.png","ImageObject",300,407,{"name":92,"@type":93},"Alexandar","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-06","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":19},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What question does the study address?","Question",{"text":112,"@type":113},"The study examines whether social isolation predicts all-cause mortality and whether that relationship varies by gender, and it considers whether age and gender matter.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which dataset and sample are used?",{"text":117,"@type":113},"The analysis uses data from the National Health and Aging Trends Study (NHATS), including 7,186 community-living respondents at baseline.",{"name":119,"@type":110,"acceptedAnswer":120},"Why do the results emphasize the operationalization of social isolation?",{"text":121,"@type":113},"The study compares two NHATS-based measures (Pohl and Cudjoe) and finds both predict mortality, but only Pohl’s measure shows a statistically significant interaction with gender, indicating that how social isolation is measured affects conclusions.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},426623,1790764454,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":19,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":8,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":81},962090768658,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","920 Innovation in Aging, 2025, Vol. 9, No. S2  \nmodels to test the main effect of social isolation and its interaction with gender, adjusting for sociodemographic, neighborhood, and health characteristics. Both measures of social isolation were significant predictors of mortality risk, though Pohl’s measure demonstrated a stronger effect than Cudjoe’s. Further, only Pohl’s measure had a statistically significant interaction effect with gender (F [2, 55] = 4.67, p =.01) . Specifically, the risk of all-cause mortality was 56% and 2.1 times higher, respectively, for somewhat and very isolated men compared to not-isolated men. Among women, the risk of mortality was 33% higher for the very-isolated relative to the not-isolated. The findings suggest that the operationalization of social isolation matters. Overall, our findings show that social isolation hastens death in older adults, particularly for men. Targeted interventions to reduce social isolation may prevent premature mortality.  \nAbstract citation ID: igaf122.3109  \nEFFECTS OF SOCIAL ISOLATION ON MORTALITY IN  \nOLDER ADULTS: DO AGE AND GENDER MATTER?  \nLydia Li, Jay Kayser, and Kyungeun Song, University of Michigan, Ann Arbor, Michigan, United States  \nSocial isolation is a recognized risk factor for adverse health outcomes, yet the magnitude of its effect on mortality and differences between genders remain unclear. This study examines whether social isolation predicts all-cause mortality and whether this relationship varies by gender. We analyzed data from the National Health and Aging Trends Study (NHATS), an ongoing nationally representative panel study of Medicare beneficiaries that began in 2011. The analytic sample included 7,186 community-living respondents at baseline, of whom a weighted 28.5% had died by 2023. Despite being a widely used construct, a gold standard to measure social isolation does not exist.  \nResearchers have developed two NHATS-based measures (Pohl and Cudjoe). We used both in weighted Cox proportional-hazard","cbCaiik1Z6Z91xpj","https://ap.wps.com/l/cbCaiik1Z6Z91xpj","pdf",47115,"English","# Study purpose\n## Data source and sample\n## Measurement of social isolation\n# Main findings\n## Overall mortality associations\n## Gender-specific effects\n# Implications","[{\"question\":\"What question does the study address?\",\"answer\":\"The study examines whether social isolation predicts all-cause mortality and whether that relationship varies by gender, and it considers whether age and gender matter.\"},{\"question\":\"Which dataset and sample are used?\",\"answer\":\"The analysis uses data from the National Health and Aging Trends Study (NHATS), including 7,186 community-living respondents at baseline.\"},{\"question\":\"Why do the results emphasize the operationalization of social isolation?\",\"answer\":\"The study compares two NHATS-based measures (Pohl and Cudjoe) and finds both predict mortality, but only Pohl’s measure shows a statistically significant interaction with gender, indicating that how social isolation is measured affects conclusions.\"}]","Effects of Social Isolation on Mortality in Older Adults: Do Age and Gender Matter? | PDF",1790641192]