[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-417415-105":59,"doc-detail-417415-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","effects-of-endocrine-disruptors-on-the-neurological-system","Effects of endocrine disruptors on the neurological system","","Increasing attention centers on endocrine disrupting chemicals for their potential impacts on neurological health. Widely present in consumer products and industrial processes, these substances can disturb hormone synthesis, expression, and function, leading to endocrine-system disorders that may cascade into neurological outcomes. This review evaluates epidemiological and experimental evidence connecting exposure to endocrine disruptors with adverse neurological effects, emphasizing neurodegenerative diseases and neurodevelopmental disorders.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/effects-of-endocrine-disruptors-on-the-neurological-system/417415/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/effects-of-endocrine-disruptors-on-the-neurological-system/417415.png","ImageObject",300,407,{"name":92,"@type":93},"dabgoudw","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What are endocrine disrupting chemicals and why are they relevant to neurological health?","Question",{"text":112,"@type":113},"They are chemical substances that can interfere with hormone synthesis, expression, transport, metabolism, and function. Because hormones regulate many neurological processes, these disruptions are linked to adverse neurological outcomes.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the evidence for this review gathered?",{"text":117,"@type":113},"A PubMed literature search was conducted using terms such as “endocrine disruptors,” “neuroendocrine effects,” “neurobehavioral effects,” and “neurodevelopmental effects,” and relevant studies were examined.",{"name":119,"@type":110,"acceptedAnswer":120},"Which neurological outcomes are highlighted in recent research?",{"text":121,"@type":113},"Recent studies emphasize correlations between endocrine disruptor exposure and neurodegenerative diseases like Alzheimer’s and Parkinson’s disease, as well as neurodevelopmental diseases such as autism spectrum disorder and attention deficit hyperactivity disorder.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},417415,1790718531,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":39,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":46,"preview_page_count":4},3985747860484,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","Turkish Journal of Medical Sciences  \n\n| Volume 55\u003Cbr>Number 7 SI-1 | Article 10 |\n| --- | --- |\n| 12-17-2025\u003Cbr>Effects of endocrine disruptors on the neurological system KADİRCAN KARATOPRAK\u003Cbr>SONER CANDER\u003Cbr>Follow this and additional works at: [https://journals.tubitak.gov.tr/medical](https://journals.tubitak.gov.tr/medical)\u003Cbr> Part of the Medical Sciences Commons |  |\n\nRecommended Citation  \nKARATOPRAK, K, & CANDER, S (2025) . Effects of endocrine disruptors on the neurological system. Turkish Journal of Medical Sciences 55 (7): 1657-1663 . [https://doi.org/10.55730/1300-0144.6127](https://doi.org/10.55730/1300-0144.6127)  \nThis work is licensed under a Creative Commons Attribution 4.0 International License.  \nThis Review Article is brought to you for free and open access by TÜBİTAK Academic Journals. It has been accepted for inclusion in Turkish Journal of Medical Sciences by an authorized editor of TÜBİTAK Academic Journals. For more information, please contact [academic.publications@tubitak.gov.tr](academic.publications@tubitak.gov.tr)  \n\n| \u003Cbr>| Turkish Journal of Medical Sciences [http://journals.tubitak.gov.tr/medical/](http://journals.tubitak.gov.tr/medical/)\u003Cbr>\u003Cbr>Review Article | Turk J Med Sci\u003Cbr>(2025) 55: 1657-1663 © TÜBİTAK\u003Cbr>doi:10.55730/1300-0144.6127 |\n| --- | --- | --- |\n\nEffects of endocrine disruptors on the neurological system  \nKadircan KARATOPRAK􀁋, Soner CANDER*􀁋  \nDivision of Endocrinology and Metabolism, Department of Internal Medicine, Faculty of Medicine, Bursa Uludağ University, Bursa,  \nTurkiye  \nReceived: 28.02.2025  Accepted/Published Online: 11.11.2025  Final Version: 17.12.2025  \nBackground/aim: There is increasing interest in endocrine disrupting chemicals because of the potential effects on neurological health. These chemicals are widely found in various consumer products and industrial processes, and can lead to serious disorders of the endocrine system by disrupting hormone synthesis, expression, and function. The aim of this review was to examine epidemiological and experimental findings by investigating the link between exposure to endocrine disrupting chemicals and adverse neurological outcomes.  \nMaterials and methods: In the preparation of this review, a PubMed literature search was conducted using the words “endocrine disruptors,” “neuroendocrine effects,” “neurobehavioral effects,” and “neurodevelopmental effects” and articles containing relevant studies were examined.  \nResults: Recent studies have shown a strong correlation between exposure to endocrine disrupting chemicals and the development of neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease, and neurodevelopmental diseases such as autism spectrum disorder and attention deficit hyperactivity disorder. The effects of common pollutants such as pesticides, bisphenol A, polychlorinated biphenyls, and heavy metals on the endocrine system have been especially emphasized.  \nConclusion: In conclusion, understanding the role played by endocrine disrupting chemicals in the development of neurological diseases will be of critical importance in the development of new strategies to prevent these diseases.  \nKey words: Endocrine disruptors, neurological diseases, Parkinson’s disease, Alzheimer’s disease, neuroendocrine effects, neurobehavioral and neurodevelopmental effects  \n1. Introduction  \nThe effects of endocrine disruptors on human health have been investigated in recent years. Endocrine disruptors are chemical substances widely found in the environment and generally originate from industrial processes. They are present at low concentrations in many natural and manufactured products such as toys, furniture, medical devices, and cosmetics, and are among the most common pollutants in the environment. They may also be found naturally in some plant-based products. People and animals may be exposed to these chemicals through various pathways. For example, there can be transfer from mother to fetus through food an","cbCaioiX03F6LKME","https://ap.wps.com/l/cbCaioiX03F6LKME","pdf",266805,"English","# Introduction\n# Association with neurological diseases\n# Materials and methods\n# Results\n# Conclusion","[{\"question\":\"What are endocrine disrupting chemicals and why are they relevant to neurological health?\",\"answer\":\"They are chemical substances that can interfere with hormone synthesis, expression, transport, metabolism, and function. Because hormones regulate many neurological processes, these disruptions are linked to adverse neurological outcomes.\"},{\"question\":\"How was the evidence for this review gathered?\",\"answer\":\"A PubMed literature search was conducted using terms such as “endocrine disruptors,” “neuroendocrine effects,” “neurobehavioral effects,” and “neurodevelopmental effects,” and relevant studies were examined.\"},{\"question\":\"Which neurological outcomes are highlighted in recent research?\",\"answer\":\"Recent studies emphasize correlations between endocrine disruptor exposure and neurodegenerative diseases like Alzheimer’s and Parkinson’s disease, as well as neurodevelopmental diseases such as autism spectrum disorder and attention deficit hyperactivity disorder.\"}]","Effects of endocrine disruptors on the neurological system | PDF",1790609111]