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While steroid injections can prevent strictures after ESD for esophageal cancer, benefit after pharyngeal ESD is unclear. Case Presentation: A 60-year-old woman underwent ESD, then received 80 mg triamcinolone acetonide into the ulcer bed to prevent scar contracture. Follow-up endoscopy at 6 weeks showed granulation tissue and complete healing without deformity by 14 weeks.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/effectiveness-of-triamcinolone-injections-in-preventing-scar-deformity-following-endoscopic-submucosal-dissection-for-pharyngeal-cancer-single-case/371279/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/effectiveness-of-triamcinolone-injections-in-preventing-scar-deformity-following-endoscopic-submucosal-dissection-for-pharyngeal-cancer-single-case/371279.png","ImageObject",300,407,{"name":92,"@type":93},"Liam","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why are local steroid injections considered after ESD for pharyngeal cancer?","Question",{"text":113,"@type":114},"ESD is effective for superficial pharyngeal cancer, but ulcer contraction can lead to pharyngeal deformity and reduced quality of life. The case explores whether triamcinolone injections can prevent scar contracture and subsequent deformity.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What treatment was given to the patient in this case report?",{"text":118,"@type":114},"After ESD, 80 mg of triamcinolone acetonide was injected into the ulcer bed to prevent scar contracture.",{"name":120,"@type":111,"acceptedAnswer":121},"What were the follow-up findings after triamcinolone injection?",{"text":122,"@type":114},"Endoscopy at 6 weeks showed granulation tissue in the surgical wound, and the lesion healed completely without pharyngeal deformity by 14 weeks post-ESD.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},371279,1790234289,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":34,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145},8796095461564,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Case Reports in Gastroenterology  \n\n| Case Rep Gastroenterol 2025;19:113–119 |  |\n| --- | --- |\n| DOI: 10.1159/000543878\u003Cbr>Received: November 13, 2024\u003Cbr>Accepted: January 13, 2025\u003Cbr>Published online: February 25, 2025 | © 2025 The Author(s) .\u003Cbr>Published by S. Karger AG, Basel [www.karger.com/crg](www.karger.com/crg) |\n\nThis article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC) ([http://www.karger.com/Services/OpenAccessLicense](http://www.karger.com/Services/OpenAccessLicense)). Usage and distribution for commercial purposes requires written permission.  \nSingle Case  \nEffectiveness of Triamcinolone Injections in Preventing Scar Deformity following Endoscopic Submucosal Dissection for Pharyngeal Cancer  \nYugo Suzuki a Shinji Ito b Tsuyoshi Ishii a Minoru Oda a Shu Hoteyaa  \na Department of Gastroenterology, Toranomon Hospital, Tokyo, Japan; bDepartment of Pathology, Toranomon Hospital, Tokyo, Japan  \nKeywords  \nPharyngeal cancer · Endoscopic submucosal dissection · Squamous cell carcinoma  \nAbstract  \nIntroduction: Endoscopic submucosal dissection (ESD) is an effective treatment for superficial pharyngeal cancer. However, pharyngeal deformity caused by postoperative ulcer contraction is a major concern and can result in a poor quality of life. While local steroid injections have been shown to prevent strictures after ESD for esophageal cancer, their effectiveness in preventing deformities following ESD for pharyngeal cancer remains unclear. Case Presentation: A 60-year-old woman with superficial pharyngeal cancer in the left pyriform sinus underwent ESD. After ESD, 80 mg of triamcinolone acetonide was injected into the ulcer bed to prevent scar contracture. The patient experienced mild pharyngeal pain, which resolved within a few days. Histopathological examination confirmed the lesion was well-differentiated SCC, with negative resection margins and no lymphovascular invasion. Follow-up endoscopy at 6 weeks showed granulation tissue in the surgical wound, which completely healed without pharyngeal deformity by 14 weeks post-ESD. Conclusion: This case demonstrated that the injection of triamcinolone in an ulcer that developed after ESD may be an effective method of preventing pharyngeal deformity caused by scar contracture.  \n© 2025 The Author(s) .  \nPublished by S. KargerAG, Basel  \nCorrespondence to:  \nYugo Suzuki, [yugo-suzuki](yugo-suzuki@ nms.ac.jp)[@](yugo-suzuki@ nms.ac.jp)[ nms.ac.jp](yugo-suzuki@ nms.ac.jp)  \nCase Reports in Gastroenterology  \nCase Rep Gastroenterol 2025;19:113–119 114  \n\n| DOI: 10.1159/000543878 | © 2025 The Author(s) . Published by S. Karger AG, Basel [www.karger.com/crg](www.karger.com/crg) |\n| --- | --- |\n\nSuzuki et al.: Steroid Injection after Pharyngeal ESD  \nIntroduction  \nEndoscopic submucosal dissection (ESD) is an effective and minimally invasive treatment for superficial pharyngeal squamous cell carcinoma (PSCC) that has been applied in clinical practice [1, 2]. Although the outcomes and long-term prognosis of PSCC are favorable [3–5], problems such as the technical difficulty of treatment in a confined space, laryngeal edema during treatment, and pharyngeal deformity caused by postoperative ulcer contraction remain. Although treatment strategies, including the use of an ultrathin endoscope and laryngeal forceps [6], for ESD have been reported, the prevention of scar contracture after ESD for PSCC has not been reported.  \nStrictures caused by ulcer scarring after ESD for esophageal cancer are major concerns that can result in a poor quality of life [7]. Therefore, local steroid injections are recommended to prevent lesions with circumferences larger than three-quarters [8] . Local steroid injections after transoral videolaryngoscopic surgery for pharyngeal cancer have been reported [9]; however, the effectiveness of local steroid injections for ulcers after ESD has not been demonstrated. We report the injection of triamcinolone in an ulc","cbCaivbTv9rZex0W","https://ap.wps.com/l/cbCaivbTv9rZex0W","pdf",1225591,"English","# Introduction\n# Case Presentation\n## Treatment and pathological findings\n## Follow-up and outcomes\n# Conclusion","[{\"question\":\"Why are local steroid injections considered after ESD for pharyngeal cancer?\",\"answer\":\"ESD is effective for superficial pharyngeal cancer, but ulcer contraction can lead to pharyngeal deformity and reduced quality of life. The case explores whether triamcinolone injections can prevent scar contracture and subsequent deformity.\"},{\"question\":\"What treatment was given to the patient in this case report?\",\"answer\":\"After ESD, 80 mg of triamcinolone acetonide was injected into the ulcer bed to prevent scar contracture.\"},{\"question\":\"What were the follow-up findings after triamcinolone injection?\",\"answer\":\"Endoscopy at 6 weeks showed granulation tissue in the surgical wound, and the lesion healed completely without pharyngeal deformity by 14 weeks post-ESD.\"}]","Effectiveness of Triamcinolone Injections in Preventing Scar Deformity following Endoscopic Submucosal Dissection for Pharyngeal Cancer - Single Case | PDF",1790191685,18]