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A retrospective study assessed two Traditional Chinese Medicine prescriptions—Fuzheng Yifei Formula (FZYF) and Fuzheng Anshen Formula (FZAS)—on psychological status, dyspnea severity, and quality-of-life outcomes. Records of 114 convalescent patients were reviewed and assessed at baseline, 7 days, 14 days, and follow-up using GHQ-12, the Modified Borg Scale, and SF-36. Both formulas improved psychological well-being and health-related quality of life, with no significant between-group difference.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/effect-of-fuzheng-series-of-formulas-on-the-psychological-state-dyspnea-and-quality-of-life-in-convalescent-covid-19-patients-a-retrospective-observational-study/449697/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/effect-of-fuzheng-series-of-formulas-on-the-psychological-state-dyspnea-and-quality-of-life-in-convalescent-covid-19-patients-a-retrospective-observational-study/449697.png","ImageObject",300,407,{"name":92,"@type":93},"RuangKosong","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":29},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the study purpose regarding COVID-19 convalescent patients?","Question",{"text":112,"@type":113},"To evaluate the clinical effects of two Traditional Chinese Medicine prescriptions on psychological state, dyspnea, and quality of life after COVID-19.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which two formulas were compared, and how were patients grouped?",{"text":117,"@type":113},"Fuzheng Yifei Formula (FZYF) and Fuzheng Anshen Formula (FZAS) were compared, with patients categorized into two groups based on the treatment regimen.",{"name":119,"@type":110,"acceptedAnswer":120},"What key outcomes improved during follow-up?",{"text":121,"@type":113},"Both groups showed improved psychological well-being, reduced dyspnea severity, and notable improvements in physical and mental health domains of SF-36.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},449697,1791171052,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":29,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":39,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":46,"preview_page_count":4},962090883219,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","®  \n Observational Study   \nEffect of Fuzheng series of formulas on the psychological state, dyspnea, and quality of life in convalescent COVID-19 patients  \nA retrospective observational study  \nLijuan Tang, MMa , Zichen Jie, MMb , Danwen Zheng, MMb , Qiaoli Hua, MMc , Shubin Cai, MMd , Chenghui Li, MMe , Yan Cai, MMf , Lianshun Jin, MMa , Rongyuan Yang, MMa , Zhongde Zhang, MMa ,*  \n\n| Abstract\u003Cbr>Post-infectious symptoms of COVID-19—such as persistent dyspnea, psychological disturbances, and reduced quality of life—continue to pose significant health challenges for convalescent patients. Traditional Chinese Medicine (TCM) has been widely used as a complementary therapeutic approach to alleviate post-COVID sequelae. This retrospective study evaluated the clinical effects of 2 TCM prescriptions, Fuzheng Yifei Formula (FZYF) and Fuzheng Anshen Formula (FZAS), on the psychological state, dyspnea, and quality of life among patients recovering from COVID-19 . Medical records of 114 COVID-19 convalescent patients treated at the Second Affiliated Hospital of Guangzhou University of Chinese Medicine were retrospectively reviewed. Based on the treatment regimen, patients were categorized into 2 groups: FZYF (n = 77) and FZAS (n = 37) . Clinical data were collected at baseline, 7 days, 14 days, and during follow-up. Changes in psychological status, dyspnea severity, and quality-of-life scores were analyzed using validated assessment tools, including the General Health Questionnaire (GHQ-12), the Modified Borg Scale, and the 36-Item Short Form Survey (SF-36) Health Survey. Both FZYF and FZAS were associated with significant improvements in psychological well-being, with mean GHQ-12 scores decreasing from 14.5 at baseline to 9 at follow-up (P \u003C .05) . Dyspnea symptoms improved across both groups, with an average reduction of 3.5 points on the Modified Borg Scale. The SF-36 results indicated notable enhancements in both physical and mental health domains, showing mean improvements of 22% and 23%, respectively. No statistically significant difference was found between the 2 formulas, although FZYF showed slightly superior benefits in respiratory symptom relief. The retrospective analysis suggests that the FZYF may help alleviate long-term respiratory and psychological symptoms among COVID-19 convalescents, thereby potentially improving their overall quality of life. The FZAS, while showing comparable trends of benefit, appeared to exert relatively greater influence on mental and emotional well-being. However, these findings should be interpreted with caution given the non-randomized design and limited sample size, and further validation through large-scale controlled studies is warranted. |\n| --- |\n| Abbreviations: COVID-19 = Coronavirus Disease 2019 , FZAS = Fuzheng Anshen Formula, FZYF = Fuzheng Yifei Formula, SF-36 = 36-Item Short Form Health Survey, TCM = Traditional Chinese Medicine. |\n| Keywords: COVID-19 , dyspnea, Fuzheng Yifei, long COVID, psychological health, quality of life, Traditional Chinese Medicine |\n\nThis study was supported by Special Project of Guangdong Provincial Chinese Medicine Hospital (YN2024MS041), The Second National Famous TCM Doctor Inheritance Office (Guangdong TCM Office Letter [2022] No. 52), Project of Building Inheritance Office for Lingnan Zhen’s Miscellaneous Diseases School (Second Hospital of Traditional Chinese Medicine [2013] No. 233), Qihuang Scholars Support Project (National TCM Renjiao Han [2022] No. 6), Special Project of Guangdong Provincial Chinese Medicine Hospital (YN2023MS36), and Zhuhai Social Development Field Science and Technology Plan-Key Project (No. 2320004000286).  \nThe authors have no conflicts of interest to disclose.  \nThe datasets generated during and/or analyzed during the current study are available from the corresponding author on reasonable request.  \na Zhang Zhongde National Famous Traditional Chinese Medicine Inheritance Studio, The Second Affiliated Hospital of Guangzho","cbCaisl4tgtHNnb1","https://ap.wps.com/l/cbCaisl4tgtHNnb1","pdf",768246,"English","# Abstract\n## Study design and participants\n## Interventions and assessment tools\n## Outcomes and findings\n## Funding and disclosures","[{\"question\":\"What was the study purpose regarding COVID-19 convalescent patients?\",\"answer\":\"To evaluate the clinical effects of two Traditional Chinese Medicine prescriptions on psychological state, dyspnea, and quality of life after COVID-19.\"},{\"question\":\"Which two formulas were compared, and how were patients grouped?\",\"answer\":\"Fuzheng Yifei Formula (FZYF) and Fuzheng Anshen Formula (FZAS) were compared, with patients categorized into two groups based on the treatment regimen.\"},{\"question\":\"What key outcomes improved during follow-up?\",\"answer\":\"Both groups showed improved psychological well-being, reduced dyspnea severity, and notable improvements in physical and mental health domains of SF-36.\"}]","Effect of Fuzheng series of formulas on the psychological state, dyspnea, and quality of life in convalescent COVID-19 patients - A retrospective observational study | PDF",1790730922]