[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-425008-105":59,"doc-detail-425008-en":135},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":128,"head_meta":130,"extra_data":132,"updated_unix":134},105,"en","dual-sensory-loss-and-rate-of-dementia-symptom-progression-in-cognitively-normal-older-adults","Dual Sensory Loss and Rate of Dementia Symptom Progression in Cognitively Normal Older Adults","","Study evaluates whether loss of both hearing and vision predicts faster dementia symptom progression among cognitively normal older adults. Data come from 21,098 participants in the National Alzheimer’s Coordinating Center Uniform Data Set, followed annually for 3.7 years on average. Clinicians classified vision impairment and hearing impairment using post-correction and unaided performance, while progression was measured by CDRSUM. Dual sensory impairment showed the highest annual increase in CDRSUM, exceeding single-modality impairment.",{"@graph":69,"@context":127},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/dual-sensory-loss-and-rate-of-dementia-symptom-progression-in-cognitively-normal-older-adults/425008/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/dual-sensory-loss-and-rate-of-dementia-symptom-progression-in-cognitively-normal-older-adults/425008.png","ImageObject",300,407,{"name":92,"@type":93},"dawugda","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-06","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",13,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119,123],{"name":110,"@type":111,"acceptedAnswer":112},"What question does the study address?","Question",{"text":113,"@type":114},"The study examines whether dual loss of hearing and vision predicts the rate of dementia symptom progression more strongly than losing either sense alone.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How were hearing and vision impairments defined?",{"text":118,"@type":114},"Vision impairment was based on difficulty with vision after correction, and hearing impairment was based on difficulty with hearing without any correction.",{"name":120,"@type":111,"acceptedAnswer":121},"What progression metric was used?",{"text":122,"@type":114},"Dementia staging and progression were measured using the Clinical Dementia Rating Sum of Boxes (CDRSUM).",{"name":124,"@type":111,"acceptedAnswer":125},"What is the main result about dual sensory impairment?",{"text":126,"@type":114},"Compared with no sensory impairment, dual impairment showed the greatest annual increase in CDRSUM, indicating greater clinical progression over time.","https://schema.org",{"og:url":83,"og:type":129,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":131,"canonical":83},"index,follow",{"doc_id":133,"site_id":62},425008,1790815201,{"code":4,"msg":5,"data":136},{"doc_id":133,"user_id":137,"nickname":92,"user_avatar":138,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":139,"file_id":140,"file_url":141,"file_type":142,"file_size":143,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":8,"language":144,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":145,"faqs":146,"seo_title":147,"seo_description":67,"update_tm":148,"read_time":81,"preview_page_count":4},3985747870947,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","1062 Innovation in Aging, 2025, Vol. 9, No. S2  \nthe longitudinal associations of hearing, vision, and dual sensory loss with clinical progression among 21,098 participants in the National Alzheimer’s Coordinating Center’s Uniform Data Set, restricting to those who were cognitively normal at baseline. Participants were 69 ±11 years at baseline, and followed annually for an average of 3.7 years, 66% were female, 78% White, 2.9% visually impaired, 18.6% hearing impaired, and 1.6% dual sensory impaired. Participants were rated by clinicians as vision impaired if they had trouble with vision after correction and as hearing impaired if they had trouble with hearing without any correction. Dementia staging was measured using the Clinical Dementia Rating Sum of Boxes (CDRSUM). Linear mixed-effects models estimated associations, adjusting for age, sex, race, education, cardiovascular disease, diabetes, hypertension, depression, and APOE-ε4 status. At baseline, sensory impairment was not significantly associated with CDRSUM; however, significant interactions with time were observed. Compared to those with no sensory impairments, individuals with dual impairment had the highest annual increase in CDRSUM (β = 0.075, 95%CI:0.048–0.102), followed by those with vision impairment alone (β = 0.028, 95%CI:0.006–0.049) and hearing impairment  \nalone (β =0.019, 95%CI:0.011–0.028). Dual sensory impairment (versus single sensory impairment) is associated with greater clinical progression of dementia symptoms over time, highlighting the potential importance of early identification and management of dual sensory loss.  \nAbstract citation ID: igaf122.3574  \nDUAL SENSORY LOSS AND RATE OF DEMENTIA  \nSYMPTOM PROGRESSION IN COGNITIVELY NORMAL  \nOLDER ADULTS  \nKathryn Hand1, Lilah Besser2, Walter Kukull3, and  \nWilla Brenowitz4, 1. Oregon Health and Science University, Portland, Oregon, United States, 2. University of Miami, Boca Raton, Florida, United States, 3. University of Washington, Seattle, Washington, United States, 4. Kaiser Permanente, Portland, Oregon, United States  \nLoss of both hearing and vision may serve as a stronger predictor of the rate of dementia symptom progression (i.e., clinical progression) than loss of either sense individually. We evaluated","cbCainzJ3APNalmd","https://ap.wps.com/l/cbCainzJ3APNalmd","pdf",946712,"English","# Abstract\n## Participants and design\n## Measures and models\n## Key findings","[{\"question\":\"What question does the study address?\",\"answer\":\"The study examines whether dual loss of hearing and vision predicts the rate of dementia symptom progression more strongly than losing either sense alone.\"},{\"question\":\"How were hearing and vision impairments defined?\",\"answer\":\"Vision impairment was based on difficulty with vision after correction, and hearing impairment was based on difficulty with hearing without any correction.\"},{\"question\":\"What progression metric was used?\",\"answer\":\"Dementia staging and progression were measured using the Clinical Dementia Rating Sum of Boxes (CDRSUM).\"},{\"question\":\"What is the main result about dual sensory impairment?\",\"answer\":\"Compared with no sensory impairment, dual impairment showed the greatest annual increase in CDRSUM, indicating greater clinical progression over time.\"}]","Dual Sensory Loss and Rate of Dementia Symptom Progression in Cognitively Normal Older Adults | PDF",1790635969]