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When drainage directs toward the left atrium, it may create a right-to-left shunt and impair whole-body oxygen delivery. This report describes a 48-year-old man with dyspnea and leg edema in whom imaging showed a double SVC with left-sided drainage directly to the left atrium.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/double-superior-vena-cava-and-anomalous-left-atrial-drainage-of-persistent-left-svc-a-case-report/441919/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/double-superior-vena-cava-and-anomalous-left-atrial-drainage-of-persistent-left-svc-a-case-report/441919.png","ImageObject",300,407,{"name":92,"@type":93},"Cipher","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-04","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What is persistent left superior vena cava (PLSVC) and how is it related to duplicated SVC?","Question",{"text":113,"@type":114},"PLSVC is a rare developmental variation of the thoracic venous system. It can occur alone or with a duplicated superior vena cava.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"Why can anomalous drainage of PLSVC toward the left atrium be clinically important?",{"text":118,"@type":114},"Left atrial drainage can produce a right-to-left shunt, potentially compromising whole-body oxygen delivery.",{"name":120,"@type":111,"acceptedAnswer":121},"How was the anomaly identified in this case?",{"text":122,"@type":114},"Contrast-enhanced CT performed for pulmonary evaluation revealed a double SVC, with the left-sided vessel connecting directly to the left atrium.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},441919,1790726689,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},687208528416,"https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc","Radiology Ca s e Reports 21 (2026) 1145 – 1149  \nAvailable online [at](at www.sciencedirect.com)[ www.sciencedirect.com](at www.sciencedirect.com)  \njournal [homepage:](homepage: www.elsevier.com/locate/radcr)[ www.elsevier.com/locate/radcr](homepage: www.elsevier.com/locate/radcr)  \n| Case Report\u003Cbr>Double superior vena cava and anomalous left atrial drainage of persistent left SVC: A case report ✩\u003Cbr>Parisa Pishdad, MDa,b, Parham Heidari, MDc, Amirhossein Soltani, MDa,b, Mohsen Salimi, MDd,∗\u003Cbr>a Department of Radiology, Shiraz University of Medical Sciences, Shiraz, Iran b Medical Imaging Research Center, Shiraz University of Medical Sciences, Shiraz, Iran c School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran\u003Cbr>d Research Center of Thoracic Oncology (RCTO), National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran |  |\n| --- | --- |\n| a r t i c l e i n f o | a b s t r a c t |\n| Article history: | Persistent left superior vena cava (PLSVC) is an uncommon developmental variation of the |\n| Received 23 July 2025 | thoracic venous system, sometimes accompanied by a duplicated superior vena cava (SVC) . |\n| Revised 22 November 2025 | While often asymptomatic when draining into the right atrium, drainage toward the left |\n| Accepted 25 November 2025 | atrium could lead to a right-to-left shunt and potential compromise of whole-body oxygen |\n|  | delivery. This report describes a 48-year-old male patient with hypertension and chronic tobacco use who was evaluated for dyspnea and leg edema. Imaging revealed a double SVC, where the left-sided vessel connected directly to the left atrium. Despite this anomaly, the |\n| Keywords: |  |\n| Persistent left superior vena cava | patient exhibited no significant hypoxemia or cyanosis, likely due to long-term compen- |\n| Vascular anomaly | satory mechanisms. This report underscores the need to consider vascular anomalies in |\n| Double superior vena cava | imaging interpretation, particularly when findings are incidental. It also underscores the |\n| Contrast-enhanced computed | role of contrast-enhanced CT in identifying rare anatomical variants and the potential for |\n| tomography | such anomalies to remain clinically silent despite physiological significance.\u003Cbr>© 2025 The Authors. Published by Elsevier Inc. on behalf of University of Washington.\u003Cbr>This is an open access article under the CC BY-NC-ND license\u003Cbr>([http://creativecommons.org/licenses/by-nc-nd/4.0/](http://creativecommons.org/licenses/by-nc-nd/4.0/)) |\n\nfrom the cranial, cervical, and superior limb regions to the right atrium (RA) [1] . Under normal circumstances, venous drainage from the right side occurs via the right brachiocephalic vein, while the left side drains through the left brachiocephalic vein [2] . Occasionally, a rare vascular variation  \n✩ Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.  \n∗ Corresponding author.  \nE-mail [address:](address: mohsenwork98@gmail.com)[ mohsenwork98@gmail.com](address: mohsenwork98@gmail.com) (M. Salimi).  \n[https://doi.org/10.1016/j.radcr.2025.11.065](https://doi.org/10.1016/j.radcr.2025.11.065)  \n1930-0433/© 2025 The Authors. Published by Elsevier Inc. on behalf of University of Washington. This is an open access article under the CC BY-NC-ND license ([http://creativecommons.org/licenses/by-nc-nd/4.0/](http://creativecommons.org/licenses/by-nc-nd/4.0/))  \nFig. 1 – A rare case of double superior vena cava (SVC) identified on contrast-enhanced CT performed using a pulmonary thromboembolism (PTE) protocol. (A) The right SVC is opacified and drains normally into the right atrium. (B) In contrast, the left SVC anomalously drains into the left atrium, representing a rare congenital vascular variant.  \nknown as a duplicated SVC maybe present, characteriz","cbCaiuz6hCGjNOSL","https://ap.wps.com/l/cbCaiuz6hCGjNOSL","pdf",822794,"English","# Case presentation","[{\"question\":\"What is persistent left superior vena cava (PLSVC) and how is it related to duplicated SVC?\",\"answer\":\"PLSVC is a rare developmental variation of the thoracic venous system. It can occur alone or with a duplicated superior vena cava.\"},{\"question\":\"Why can anomalous drainage of PLSVC toward the left atrium be clinically important?\",\"answer\":\"Left atrial drainage can produce a right-to-left shunt, potentially compromising whole-body oxygen delivery.\"},{\"question\":\"How was the anomaly identified in this case?\",\"answer\":\"Contrast-enhanced CT performed for pulmonary evaluation revealed a double SVC, with the left-sided vessel connecting directly to the left atrium.\"}]","Double superior vena cava and anomalous left atrial drainage of persistent left SVC - A case report | PDF",1790698087,13]