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Using VA barcode medication administration systems, data from 45,183 residents aged 65+ (2006–2019) quantified antihistamine and non-antihistamine anticholinergic exposure and linked it with demographics, conditions, labs, and functional status. Antihistamine use was lower in dementia (6.5% vs 10.7% median weeks), while non-antihistamine use was somewhat lower among dementia.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/discontinuation-of-anticholinergic-medications-among-va-nursing-home-residents-with-and-without-dementia-abstract/421859/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/discontinuation-of-anticholinergic-medications-among-va-nursing-home-residents-with-and-without-dementia-abstract/421859.png","ImageObject",300,407,{"name":92,"@type":93},"Terk","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":29},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why is it challenging to study anticholinergic medication use in electronic health records?","Question",{"text":112,"@type":113},"Over-the-counter anticholinergic medications, such as antihistamines, are difficult to capture in electronic health records.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How did the study capture anticholinergic medications in VA nursing homes?",{"text":117,"@type":113},"Providers used a barcode medication administration system to administer and track medications, enabling capture of all anticholinergics, including over-the-counter ones.",{"name":119,"@type":110,"acceptedAnswer":120},"What proportion of residents discontinued non-antihistamine anticholinergic medications before discharge or death?",{"text":121,"@type":113},"Over 80% of residents with and without dementia discontinued their non-antihistamine anticholinergic medication before discharge or death.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},421859,1790791317,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":29,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":8,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":81,"preview_page_count":4},1099525198933,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","108 Innovation in Aging, 2025, Vol. 9, No. S2  \nAbstract citation ID: igaf122.357  \nDISCONTINUATION OF ANTICHOLINERGIC  \nMEDICATIONS AMONG VA NURSING HOME  \nRESIDENTS WITH AND WITHOUT DEMENTIA  \nCellas Hayes, Stanford University, Stanford, California, United States  \nAnticholinesterase drugs are used commonly among older adults despite their known adverse effects on cognitive outcomes.  \nA major challenge in studying their use is the difficulty of capturing over-the-counter anticholinergic medications, such as antihistamines, in electronic health records. In Veterans Affairs (VA) nursing homes, healthcare providers administer and track medications using a barcode medication administration system, which allows us to capture all anticholinergic medications, including over-the-counter ones. The present study used data from 45,183 VA long-term care residents (admitted between 2006 – 2019) aged 65 years and older. We captured antihistamine and non-antihistamine anticholinergic medication use, and linked with data on demographics, chronic conditions, laboratory measures, and functional status data from the minimum dataset.  \nResidents were an average of 78.1 years old and 2.5% were women and 44.5% had dementia. The median length of stay was  \n9 months. Residents with dementia used antihistamine anticholinergics for a median of 6.5%(0.15–100%) weeks of their stay, compared to 10.7%(0.13–100%) in those without dementia.  \nAdditionally, 44% of residents with dementia used non-antihistamine anticholinergic medications at some point during their stay compared with 56% of those without dementia.  \nOver 80% of residents with and without dementia discontinued their non-antihistamine anticholinergic medication before discharge or death. Anticholinergic medication use is high among nursing home residents but discontinuation is common.","cbCaikqscoc9LtXa","https://ap.wps.com/l/cbCaikqscoc9LtXa","pdf",153910,"English","# Abstract\n## Background and challenge\n## Data source and cohort\n## Key results\n## Conclusion","[{\"question\":\"Why is it challenging to study anticholinergic medication use in electronic health records?\",\"answer\":\"Over-the-counter anticholinergic medications, such as antihistamines, are difficult to capture in electronic health records.\"},{\"question\":\"How did the study capture anticholinergic medications in VA nursing homes?\",\"answer\":\"Providers used a barcode medication administration system to administer and track medications, enabling capture of all anticholinergics, including over-the-counter ones.\"},{\"question\":\"What proportion of residents discontinued non-antihistamine anticholinergic medications before discharge or death?\",\"answer\":\"Over 80% of residents with and without dementia discontinued their non-antihistamine anticholinergic medication before discharge or death.\"}]","DISCONTINUATION OF ANTICHOLINERGIC MEDICATIONS AMONG VA NURSING HOME RESIDENTS WITH AND WITHOUT DEMENTIA - Abstract | PDF",1790625710]