[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-458608-105":3,"detail-sidebar-cat-0-en-105":81,"doc-detail-458608-en":130},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","diode-laser-versus-scalpel-in-the-surgical-treatment-of-infant-ankyloglossia-a-randomized-parallel-double-blind-controlled-clinical-trial","Diode laser versus scalpel in the surgical treatment of infant ankyloglossia - a randomized, parallel, double-blind, controlled clinical trial","","Ankyloglossia (tongue-tie) can compromise breastfeeding, swallowing, and maxillomandibular development, making effective management essential. This randomized, parallel, double-blind controlled clinical trial compared diode laser frenotomy with conventional scalpel frenotomy in infants aged 0–6 months with severe ankyloglossia (BTAT 0–3; n=40/group). Outcomes assessed tongue function, wound healing, perioperative pain, and breastfeeding performance at D0, D7, and D14.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/diode-laser-versus-scalpel-in-the-surgical-treatment-of-infant-ankyloglossia-a-randomized-parallel-double-blind-controlled-clinical-trial/458608/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/diode-laser-versus-scalpel-in-the-surgical-treatment-of-infant-ankyloglossia-a-randomized-parallel-double-blind-controlled-clinical-trial/458608.png","ImageObject",300,407,{"name":42,"@type":43},"Mabel","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-11-03","2026-09-30",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",7,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What conditions and age group were included in the trial?","Question",{"text":63,"@type":64},"Infants aged 0–6 months diagnosed with severe ankyloglossia (BTAT score 0–3) were included.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"How did the diode laser and scalpel techniques compare overall?",{"text":68,"@type":64},"Both diode laser and scalpel groups showed significant functional improvements and weight gain over time, with no significant intergroup differences for most outcomes.",{"name":70,"@type":61,"acceptedAnswer":71},"Which technique showed better breastfeeding performance at day 7?",{"text":72,"@type":64},"On D7, the scalpel group demonstrated superior breastfeeding performance, with LATCH (p=0.003) and IBFAT (p=0.024) results favoring scalpel.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},458608,1790980649,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,109,114,119,122,126],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":107,"slug":108},40,"healthcare",{"id":110,"doc_module":4,"doc_module_name":25,"category_name":111,"show_sort_weight":112,"slug":113},8,"Research & Report",30,"research-report",{"id":115,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},9,"Religion & Spirituality",20,"religion-spirituality",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":117,"slug":121},"World Cup","world-cup",{"id":123,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":123,"slug":125},10,"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":97,"slug":129},19,"General","general",{"code":4,"msg":82,"data":131},{"doc_id":79,"user_id":132,"nickname":42,"user_avatar":133,"doc_module":4,"category_id":55,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":123,"language":139,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":12,"update_tm":143,"read_time":144,"preview_page_count":4},7971474920318,"https://ap-avatar.wpscdn.com/avatar/74000ee537e6b0ca360?x-image-process=image/resize,m_fixed,w_180,h_180&k=1788430171632181674","Carneiro etal. BMC Pediatrics (2026) 26:22 BMC Pediatrics  \n[https://doi.org/10.1186/s12887-025-06307-y](https://doi.org/10.1186/s12887-025-06307-y)  \nRESEARCH Open Access  \nDiode laser versus scalpel in the surgical treatment of infant ankyloglossia: a randomized, parallel, double-blind, controlled clinical trial  \nMariana Laprovitera Teixeira Carneiro 1, Maria Elisa Quezado Lima Verde 1,2*, Maria Fernanda da Silva Nascimento 1, João Emanuel Sousa de Almeida 1, Maria Clara Mendes Gomes3, Rebeca Neneza Dias Barboza3,  \nSheyla Cristinty Rodrigues Mendes3, Laís Fernandes Pontes Mendonça3, Luzia Rayane Gomes de Lima3, Barbhara Girão Costa Rodrigues3, Gustavo Mendes de Oliveira3, Paulo Goberlânio de Barros Silva 1,3 and Juliana Ximenes Damasceno 1,4  \nAbstract  \nBackground Ankyloglossia can impair vital functions such as breastfeeding, swallowing, and maxillomandibular development, making effective treatment essential. This study aimed to compare the clinical effectiveness of diode laser (DL) and scalpel (SC) frenotomy in infants with severe ankyloglossia.  \nMethods This randomized, parallel, double-blind clinical trial evaluated the efficacy of diode laser surgery compared to conventional scalpel frenotomy in infants aged 0–6 months, all diagnosed with severe ankyloglossia (BTAT score 0–3) (n = 40/group) . Patients were assessed at D0 (pre-, trans-, and/or 30 min postoperative), D7, and D14 using specific instruments according to each outcome: tongue repositioning and frenulum release (BTAT and Tongue Test), wound healing (Landry index), perioperative pain (CRIES scale), and breastfeeding performance (body mass variation, LATCH, and IBFAT scales) .  \nResults Both the diode laser (DL) and scalpel (SC) groups showed significant functional improvements and weight gain over time (p \u003C 0. 001), with no significant intergroup differences in most outcomes (p >0. 05) . However, on D7, the SC group demonstrated superior breastfeeding performance (LATCH: p= 0 . 003; IBFAT: p= 0 . 024) . Both groups exhibited reduced pain and progressive healing (p \u003C 0. 001) . In the diode laser group, a negative correlation was found between total energy applied and healing quality at D14 (r = − 0 . 355; p = 0 . 027) .  \nConclusions Findings suggest both techniques are clinically effective, but laser parameters may influence healing. Further studies are warranted to optimize laser protocols in pediatric ankyloglossia surgery.  \nTrial registration RBR466cykz November 13th, 2024.  \n*Correspondence:  \nMaria Elisa Quezado Lima Verde [elisalimaverde@gmail.com](elisalimaverde@gmail.com)  \nFull list of author information is available at the end of the article  \n© The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit [http://creativecommons.org/l](http://creativecommons.org/l)icenses/by/4.0/.  \nCarneiro et al. BMC Pediatrics (2026) 26:22 Page 2 of 10  \nKeywords Laser therapy, Ankyloglossia, Infant  \nBackground  \nThe lingual frenulum is a fibrous connective tissue structure that connects the ventral surface of the tongue to the floor of the mouth [1]. Along with the labial frenulum, it plays a key role in the function of the lingual and perioral muscles, being essential for speech, swallowing, sucking, and br","cbCaiepxhpMtcMjb","https://ap.wps.com/l/cbCaiepxhpMtcMjb","pdf",1832105,"English","# Background\n## Clinical impact of ankyloglossia\n## Diagnostic tools and lack of consensus\n# Methods\n## Trial design and participants\n## Outcome measures and assessment times\n# Results\n## Functional and weight outcomes\n## Breastfeeding performance and pain/healing\n# Conclusions\n## Clinical effectiveness and need for protocol optimization","[{\"question\":\"What conditions and age group were included in the trial?\",\"answer\":\"Infants aged 0–6 months diagnosed with severe ankyloglossia (BTAT score 0–3) were included.\"},{\"question\":\"How did the diode laser and scalpel techniques compare overall?\",\"answer\":\"Both diode laser and scalpel groups showed significant functional improvements and weight gain over time, with no significant intergroup differences for most outcomes.\"},{\"question\":\"Which technique showed better breastfeeding performance at day 7?\",\"answer\":\"On D7, the scalpel group demonstrated superior breastfeeding performance, with LATCH (p=0.003) and IBFAT (p=0.024) results favoring scalpel.\"}]","Diode laser versus scalpel in the surgical treatment of infant ankyloglossia - a randomized, parallel, double-blind, controlled clinical trial | PDF",1790753835,25]