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Methods: A single-blind randomized controlled trial was conducted in primary care with participants aged ≥50 years with SCI or MCI, randomized to a personalized computerized cognitive stimulation program, a stimulating leisure activities program, or control. Results: Compared to control, computerized stimulation reduced anxiety post-intervention and depressive symptoms at 6 months, while leisure activities improved global cognition after intervention and at 6 months. Conclusion: Both approaches offer complementary benefits.",{"@graph":69,"@context":121},[70,84,104],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/differential-effects-of-computerized-cognitive-stimulation-versus-stimulating-leisure-activities-on-mood-and-global-cognition-in-adults-with-subjective-and-mild-cognitive-impairment-a-randomized-controlled-trial/433402/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":98,"encodingFormat":97,"isAccessibleForFree":99,"interactionStatistic":100},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/differential-effects-of-computerized-cognitive-stimulation-versus-stimulating-leisure-activities-on-mood-and-global-cognition-in-adults-with-subjective-and-mild-cognitive-impairment-a-randomized-controlled-trial/433402.png","ImageObject",300,407,{"name":92,"@type":93},"CatatanPagi","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-09-29",true,{"@type":101,"interactionType":102,"userInteractionCount":8},"InteractionCounter",{"@type":103},"ViewAction",{"@type":105,"mainEntity":106},"FAQPage",[107,113,117],{"name":108,"@type":109,"acceptedAnswer":110},"How were participants assigned to study groups?","Question",{"text":111,"@type":112},"Adults aged ≥50 years with subjective cognitive impairment or mild cognitive impairment were randomized to a computerized cognitive stimulation program, a stimulating leisure activities program, or a control group.","Answer",{"name":114,"@type":109,"acceptedAnswer":115},"What outcomes were assessed in the trial?",{"text":116,"@type":112},"The primary outcome was global cognition, and secondary outcomes included memory, verbal fluency, daily functioning, and mood.",{"name":118,"@type":109,"acceptedAnswer":119},"What were the main findings comparing interventions with the control group?",{"text":120,"@type":112},"Computerized cognitive stimulation showed greater reductions in anxiety after the intervention and lower depressive symptoms at 6-month follow-up, while stimulating leisure activities improved global cognition post-intervention and at 6 months.","https://schema.org",{"og:url":83,"og:type":123,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":125,"canonical":83},"index,follow",{"doc_id":127,"site_id":62},433402,1790695418,{"code":4,"msg":5,"data":130},{"doc_id":127,"user_id":131,"nickname":92,"user_avatar":132,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":133,"file_id":134,"file_url":135,"file_type":136,"file_size":137,"view_count":8,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":138,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},962090894170,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","DEL SISTEMA SANITARIO DE NAVARRA  \nAn Sist Sanit Navar 2025; 48(3): e1136  \n[https://doi.org/10.23938/ASSN.1136](https://doi.org/10.23938/ASSN.1136)  \neISSN: 2340-3527 • ISSN: 1137-6627  \n[https://recyt.fecyt.es/index.php/ASSN/](https://recyt.fecyt.es/index.php/ASSN/)  \nORIGINAL ARTICLE  \nDifferential effects of computerized cognitive stimulation versus  \nstimulating leisure activities on mood and global cognition in adults with subjective and mild cognitive impairment: A randomized controlled trial Efectos diferenciales de la estimulación cognitiva computarizaday las actividades de ocio estimulantes sobre el estado de ánimoy la cogniciónglobal en adultos con deterioro cognitivo subjetivo y leve: Ensayo controlado aleatorizado Isabel Gómez-Soria1,2, Juan Nicolás Cuenca-Zaldivar3,4,5, Bárbara Oliván-Blázquez2,6*,  \nAlejandra Aguilar-Latorre2,7, Rosa Mª Magallón-Botaya2,8, Estela Calatayud1,2  \n\n| ABSTRACT | RESUMEN |\n| --- | --- |\n| Background. Mild Cognitive Impairment (MCI) involves both subjec- | Fundamento. El deterioro cognitivo leve (DCL) se caracteriza por |\n| tive and objective cognitive decline with relatively preserved daily | deterioro cognitivo subjetivo y objetivo con funcionamiento diario |\n| functioning, whereas Subjective Cognitive Impairment (SCI) refers | relativamente preservado, mientras que el deterioro cognitivo sub- |\n| to perceived decline without measurable deficits. This study aimed | jetivo (DCS) implica percepción de deterioro cognitivo sin déficits |\n| to compare the effects of a personalized computerized cognitive | medibles. Este estudio evalúa los efectos de un programa persona- |\n| stimulation (CS) program (IG1) and a stimulating leisure activities | lizado de estimulación cognitiva computarizada frente a actividades |\n| program (IG2) in adults with MCI and SCI. | de ocio estimulantes en adultos con DCL y DCS. |\n| Methods. A single-blind randomized controlled trial was conducted | Métodos. Ensayo controlado aleatorizado simple ciego realizado en |\n| in primary care with participants aged ≥50 years with SCI or MCI. | Atención Primaria con participantes de ≥50 años, con DCL o DCS, asig- |\n| Participants were randomized to IG1, IG2), or a control group (CG). | nados aleatoriamente a dos grupos de intervención (GI1, GI2) y a un |\n| IG1 completed personalized computerized CS for 30 minutes/day, 5 | grupo control (GC). El GI1 realizó estimulación cognitiva computarizada |\n| days/week, for 8 weeks. IG2 engaged in 2-5 stimulating leisure acti- | personalizada 30 minutos/día, 5 días/semana, durante 8 semanas. El GI2 |\n| vities per week for the same period. The primary outcome was glo- | participó en 2-5 actividades de ocio estimulantes/semana durante el mis- |\n| bal cognition; secondary outcomes included memory, verbal fluen- | mo periodo. El resultado principal fue la cognición global y los secunda- |\n| cy, daily functioning, and mood. | rios memoria, fluidez verbal, funcionamiento diario y estado de ánimo. |\n| Results. Fifty-nine participants were enrolled in the study, 44 with | Resultados. Se reclutaron 59 participantes, 15 con DCL. Frente al |\n| SCI and 15 with MCI. Compared to CG, IG1 showed greater reductions in anxiety post-intervention (2.07; 95%CI: 0.93-3.22 vs. 4.34; 95%CI: 3.22-5.46) and lower depressive symptoms at 6-month fol- | GC, el GI1 redujo más la ansiedad post-intervención (2,074; IC95%: 0,927-3,222 vs. 4,338; IC95%: 3.22-5.456) y los síntomas depresivos alos 6 meses (3,407; IC95%: 2,047-4,767 vs. 5,615; IC95%: 4,262-6,968), |\n| low-up (3.41; 95%CI: 2.05-4.77 vs. 5.62; 95%CI: 4.26-6.97). IG2 par- | mientras que el GI2 mejoró la cognición global tanto post-interven- |\n| ticipants demonstrated improved global cognition post-intervention (29.2; 95%CI: 27.625-30.776) and at 6 months (28.78; 95%CI: 27.16- 30.42) relative to CG (30.626; 95%CI: 28.99-32.27). | ción (29,2; IC95%: 27,625-30.776) como a los 6 meses (28,782; IC95%: 27,163-30,402) respecto del GC (30,626; IC95%: 28,987-32,265). ","cbCaiuMGT3OESVlD","https://ap.wps.com/l/cbCaiuMGT3OESVlD","pdf",1538331,15,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusion","[{\"question\":\"How were participants assigned to study groups?\",\"answer\":\"Adults aged ≥50 years with subjective cognitive impairment or mild cognitive impairment were randomized to a computerized cognitive stimulation program, a stimulating leisure activities program, or a control group.\"},{\"question\":\"What outcomes were assessed in the trial?\",\"answer\":\"The primary outcome was global cognition, and secondary outcomes included memory, verbal fluency, daily functioning, and mood.\"},{\"question\":\"What were the main findings comparing interventions with the control group?\",\"answer\":\"Computerized cognitive stimulation showed greater reductions in anxiety after the intervention and lower depressive symptoms at 6-month follow-up, while stimulating leisure activities improved global cognition post-intervention and at 6 months.\"}]","Diferential effects of computerized cognitive stimulation versus stimulating leisure activities on mood and global cognition in adults with subjective and mild cognitive impairment: A randomized controlled trial | PDF",1790663988,38]