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This retrospective case series analyzes MRI parameters for lymphomas (n=6), adenocarcinomas (n=2), and inflammatory polyps (n=4), including T1-, T2-, contrast-enhanced T1-weighted imaging, and diffusion-weighted imaging with apparent diffusion coefficient (ADC) values. All lymphomas show hypointense signal on contrast-enhanced T1WI and more frequent homogeneous enhancement than other lesions. ADC values are significantly lower in lymphomas than in adenocarcinomas and inflammatory polyps, suggesting MRI may distinguish lymphoma from other intestinal tumors.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/differential-diagnosis-using-mri-of-canine-intestinal-neoplasms-including-lymphoma-adenocarcinoma-and-inflammatory-polyp-case-series/356209/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/differential-diagnosis-using-mri-of-canine-intestinal-neoplasms-including-lymphoma-adenocarcinoma-and-inflammatory-polyp-case-series/356209.png","ImageObject",300,407,{"name":92,"@type":93},"moss~","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-03","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What canine intestinal neoplasm types were included in the study?","Question",{"text":112,"@type":113},"The study included lymphomas (n=6), adenocarcinomas (n=2), and inflammatory polyps (n=4) in dogs.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which MRI features most clearly differentiated lymphoma from other lesions?",{"text":117,"@type":113},"Lymphomas were characterized by hypointense signal on contrast-enhanced T1WI and more frequent homogeneous enhancement. They also showed significantly lower ADC values than adenocarcinomas and inflammatory polyps.",{"name":119,"@type":110,"acceptedAnswer":120},"Did T1WI/T2WI findings or qualitative DWI and intestinal obstruction differ across tumor types?",{"text":121,"@type":113},"No significant differences were observed among intestinal neoplasms for T1WI and T2WI signal characteristics, qualitative DWI, or the presence of intestinal obstruction.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},356209,1790189233,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":39,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":46},962090895452,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Veterinary Radiology & Ultrasound   \n ORIGINAL RESEARCH   \nDifferential Diagnosis Using MRI of Canine Intestinal Neoplasms, Including Lymphoma, Adenocarcinoma, and Inflammatory Polyp: Case Series  \nToshiyuki Tanaka1, 2   Yusuke Wada3  Mizuki Tomihari1   Takashi Hasegawa1   \n1 Laboratory of Veterinary Advanced Diagnosis and Treatment, School of Veterinary Science, Osaka Metropolitan University, Osaka, Japan  2 Kinki Animal  \nMedical Training Institute & Veterinary Clinic, Osaka, Japan  3 Osaka Hospital, Japan Animal Referral Medical Center, Osaka, Japan Correspondence: Toshiyuki Tanaka ([toshiyukitanaka001@gmail.com](toshiyukitanaka001@gmail.com))  \nReceived: 10 February 2026  Revised: 12 August 2026  Accepted: 19 August 2026  \nKeywords: abdomen | apparent diffusion coefficient (ADC) | computed tomography (CT) | diffusion-weighted imaging (DWI) | dog | magnetic resonance imaging (MRI)  \nABSTRACT  \nNo studies have evaluated magnetic resonance imaging (MRI) findings of intestinal neoplasms in veterinary medicine. We hypothesized that MRI findings would differ among intestinal neoplasms in veterinary medicine. This study retrospectively assessed the MRI findings of intestinal neoplasms, including lymphomas (n = 6), adenocarcinomas (n = 2), and inflammatory polyps (n = 4) in dogs. The following MRI parameters were recorded: neoplasm signal intensity (SI) on T1-weighted images (T1WI), T2-weighted images (T2WI), contrast-enhanced T1WI (C-T1WI), and diffusion-weighted images (DWI); contrast enhancement pattern on C-T1WI; the presence of intestinal obstruction; and apparent diffusion coefficient (ADC) values. All lymphomas (6 of 6) showed hypointense SI on C-T1WI, whereas adenocarcinomas (0 of 2) and inflammatory polyps (0 of 4) did not (p = 0.002) . Lymphomas (5 of 6) showed homogeneous enhancement significantly more frequently than adenocarcinoma (0 of 2) and inflammatory polyps (0 of 4) (p = 0.02) . Regarding SI of T1WI, T2WI, and qualitative DWI, and the presence of intestinal obstruction, no significant differences were observed among intestinal neoplasms. The ADC values of lymphomas (0.58 ± 0.18 × 10−3 mm2 /s) were significantly lower than adenocarcinomas (1.27 ± 0.007 × 10−3 mm2 /s, p = 0.01) and inflammatory polyps (1.56 ± 0.3 × 10−3 mm2 /s, p = 0.0002). Lymphomas showed homogeneous low enhancement and significantly lower ADC values compared with adenocarcinomas and inflammatory polyps by MRI. These MRI findings may help differentiate intestinal lymphoma from other intestinal neoplasms.  \n1  Introduction  \nImaging modalities used in veterinary medicine to investigate intestinal tumors include radiography, ultrasound, and computed tomography (CT) . Recent studies have reported the use of CTin intestinal tumor differentiation [1–5] . However, CT of the intestine has some limitations. First, CT findings of intestinal tumors overlap across different types of tumors [5] . Second, CT has lower soft tissue contrast resolution in soft tissues and cannot effectively distinguish the layers of the bowel wall [6] .  \nBecause magnetic resonance imaging (MRI) allows for the acquisition of multi-parameter images, it can reduce radiation exposure from CT and the use of iodinated contrast agents [7] . MRI provides excellent soft tissue contrast, detailed anatomical information, and information on lesions on hemorrhage, necrosis, edema, cystic and myxoid degeneration, and fibrosis [7, 8] . With recent advances in MRI technology, including high-resolution three-dimensional (3D) gradient-recalled echo (GRE) sequencesand diffusion-weighted imaging (DWI), MRI provides improved diagnostic accuracy [9–11]. DWI has the potential to assess tissues  \nThis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.  \n© 2026 The Author(s) . Veterinary Radiology & Ultrasound published by Wiley Periodicals LLC on behalf of ","cbCaib2Dxc9Qo5aS","https://ap.wps.com/l/cbCaib2Dxc9Qo5aS","pdf",1052697,"English","# Abstract\n# Introduction\n# Materials and Methods","[{\"question\":\"What canine intestinal neoplasm types were included in the study?\",\"answer\":\"The study included lymphomas (n=6), adenocarcinomas (n=2), and inflammatory polyps (n=4) in dogs.\"},{\"question\":\"Which MRI features most clearly differentiated lymphoma from other lesions?\",\"answer\":\"Lymphomas were characterized by hypointense signal on contrast-enhanced T1WI and more frequent homogeneous enhancement. They also showed significantly lower ADC values than adenocarcinomas and inflammatory polyps.\"},{\"question\":\"Did T1WI/T2WI findings or qualitative DWI and intestinal obstruction differ across tumor types?\",\"answer\":\"No significant differences were observed among intestinal neoplasms for T1WI and T2WI signal characteristics, qualitative DWI, or the presence of intestinal obstruction.\"}]","Differential Diagnosis Using MRI of Canine Intestinal Neoplasms - Including Lymphoma, Adenocarcinoma, and Inflammatory Polyp: Case Series | PDF",1790124075]