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Axial and sagittal T2-weighted images were interpreted independently by blinded radiologists, including assessment of uterine attachment and measurement of tumor-uterus angles across histologic subtypes.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/differences-in-the-position-of-endometriosis-associated-and-non-associated-ovarian-cancer-relative-to-the-uterus-study-findings-using-mri/381474/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/differences-in-the-position-of-endometriosis-associated-and-non-associated-ovarian-cancer-relative-to-the-uterus-study-findings-using-mri/381474.png","ImageObject",300,407,{"name":42,"@type":43},"Sarah ","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-29","2026-09-24",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",11,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"Why is preoperative histological assessment of ovarian cancer important in this study?","Question",{"text":63,"@type":64},"Preoperative assessment of ovarian cancer histology is essential to determine the appropriate treatment strategy, and tumor location may help support that assessment.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"How was tumor position evaluated relative to the uterus?",{"text":68,"@type":64},"MRI T2-weighted sagittal and axial images of the uterine body long axis were analyzed. Radiologists judged whether the ovarian tumor was attached to the uterus and measured the angle between the uterus and the tumor.",{"name":70,"@type":61,"acceptedAnswer":71},"What positional differences were found between EAOCs and non-EAOCs?",{"text":72,"@type":64},"EAOCs were positioned significantly more posteriorly to the uterus than non-EAOCs. 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Insights into Imaging (2023) 14:136 [https://doi.org/10.1186/s13244-023-01468-9](https://doi.org/10.1186/s13244-023-01468-9)  \nORIGINAL ARTICLE Open Access  \nDifferences in the position  \nof endometriosis-associated and non-associated ovarian cancer relative to the uterus  \nTsukasa Saida1* , Kensaku Mori 1, Toshitaka Ishiguro 1, Yukihisa Saida2, Toyomi Satoh3 and Takahito Nakajima 1  \nAbstract  \nBackground Preoperative assessment of the histological type of ovarian cancer is essential to determine the appropriate treatment strategy. Tumor location may be helpful in this regard. The purpose of this study was to com  \npare the position of endometriosis-associated (EAOCs) and non-associated (non-EAOCs) ovarian cancer relative to the uterus using MRI.  \nMethods This retrospective study included patients with pathologically confirmed malignant epithelial ovarian tumors who underwent MRI at our hospital between January 2015 and January 2023. T2-weighted images of the sagittal and axial sections of the long axis of the uterine body were used for the analysis. Three blinded experienced radiologists independently interpreted the images and assessed whether the ovarian tumor was attached to the uterus, and the angle between the uterus and the tumor was measured. The presence of attachment and the measured angles were compared for each histology. In addition, the angles between EAOCs, including endometrioid carcinomas (ECs) and clear cell carcinomas (CCCs), were compared with non-EAOCs.  \nResults In total, 184 women (mean age, 56 years; age range, 20–91 years) were evaluated. High-grade serous carcinomas (HGSCs) were significantly smaller than the others and had significantly less uterine attachment than CCCs (p \u003C 0.01 for all readers) . According to the mean of the measured angles, CCCs were positioned significantly more posteriorly than HGSCs and mucinous carcinomas (p \u003C 0. 02), and EAOCs were positioned significantly more posteriorly to the uterus than non-EAOCs (p \u003C 0. 01) .  \nConclusion HGSCs are often not attached to the uterus, and EAOCs are positioned more posteriorly to the uterus than non-EAOCs.  \nCritical relevance statement High-grade serous carcinomas were often not attached to the uterus, and endometriosis-associated ovarian cancers were positioned more posteriorly to the uterus than non-endometriosis-associated ovarian cancers. Key points  \n• The position of the ovarian tumor can be determined using MRI.  \n• High-grade serous carcinomas had less attachment to the uterus.  \n• Endometriosis-associated cancers were positioned more posteriorly to the uterus.  \n• The location of ovarian tumors is helpful in estimating histology.  \nKeywords Ovary, Carcinoma, Magnetic resonance imaging, Location  \n*Correspondence:  \nTsukasa Saida  \n[saida_sasaki_tsukasa@md.tsukuba.ac.jp](saida_sasaki_tsukasa@md.tsukuba.ac.jp)  \nFull list of author information is available at the end of the article  \n© The Author(s) 2023. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit [http://creativecommons.org/licenses/by/4.0/](http://creativecommons.org/licenses/by/4.0/.)[.](http://creativecommons.org/licenses/by/4.0/.)  \nSaida et al. Insights into Imaging (2023) 14:136 Page 2 of 10  \nGraphical abstract ","cbCaiv0W1qX9NlVy","https://ap.wps.com/l/cbCaiv0W1qX9NlVy","pdf",1931910,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusion\n## Key points\n# Introduction\n## O-RADS MRI and ovarian lesion risk stratification\n## Ovarian carcinogenesis model (types I and II)","[{\"question\":\"Why is preoperative histological assessment of ovarian cancer important in this study?\",\"answer\":\"Preoperative assessment of ovarian cancer histology is essential to determine the appropriate treatment strategy, and tumor location may help support that assessment.\"},{\"question\":\"How was tumor position evaluated relative to the uterus?\",\"answer\":\"MRI T2-weighted sagittal and axial images of the uterine body long axis were analyzed. Radiologists judged whether the ovarian tumor was attached to the uterus and measured the angle between the uterus and the tumor.\"},{\"question\":\"What positional differences were found between EAOCs and non-EAOCs?\",\"answer\":\"EAOCs were positioned significantly more posteriorly to the uterus than non-EAOCs. Additionally, high-grade serous carcinomas showed less uterine attachment than other histologies.\"}]","Differences in the position of endometriosis-associated and non-associated ovarian cancer relative to the uterus - study findings using MRI | PDF",1790245452,25]