[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-371794-105":59,"doc-detail-371794-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","dietary-monounsaturated-fatty-acids-in-relation-to-risk-of-gastric-cancer","Dietary Monounsaturated Fatty Acids in Relation to Risk of Gastric Cancer","","Monounsaturated fatty acids (MUFA) contain a single double bond and are linked to antioxidant, cholesterol-lowering, and anti-inflammatory effects. Evidence on MUFA intake and gastric cancer risk remains inconsistent across populations. A hospital-based case–control study in Vietnam evaluated this association using 1182 incident gastric cancer cases and 2965 controls, with MUFA intake estimated from a validated food frequency questionnaire.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/dietary-monounsaturated-fatty-acids-in-relation-to-risk-of-gastric-cancer/371794/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/dietary-monounsaturated-fatty-acids-in-relation-to-risk-of-gastric-cancer/371794.png","ImageObject",300,407,{"name":92,"@type":93},"Aran","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the main focus of this study?","Question",{"text":112,"@type":113},"The study evaluates the association between dietary monounsaturated fatty acid (MUFA) intake and the risk of gastric cancer in Vietnam.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was MUFA intake measured?",{"text":117,"@type":113},"MUFA intake was quantified using a validated semi-quantitative food frequency questionnaire (FFQ).",{"name":119,"@type":110,"acceptedAnswer":120},"What were the key findings regarding gastric cancer risk?",{"text":121,"@type":113},"Higher MUFA intake showed an inverse association with gastric cancer risk, with results consistent across sexes and age groups (\u003C60 and ≥60 years).","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},371794,1790309190,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":41},137455076865,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","European Journal of Nutrition (2025) 64:268  \n[https://doi.org/10.1007/s00394-025-03773-z](https://doi.org/10.1007/s00394-025-03773-z)  \nORIGINAL CONTRIBUTION  \nDietary monounsaturated fatty acids in relation to risk of gastric cancer  \nNgoanTran Le1 · Yen Thi-Hai Pham2,3,4 · Linh Thuy Le5 · Dai Duc Nguyen6 · Xingyi Guo7,8 · Hung N. Luu2,3,4  \nReceived: 3 August 2024 / Accepted: 22 July 2025 / Published online: 31 August 2025 © The Author(s) 2025  \nAbstract  \nBackground Monounsaturated fatty acids (MUFA) are considered healthy fats with a single double bond in the constituent fatty acids and have antioxidant properties, cholesterol-lowering properties, and ability to reduce chronic inflammation. Evidence regarding the effect of MUFA intake on gastric cancer risk is inconclusive among diverse populations. Given the differences in dietary composition among different racial/ethnicities, we aimed to evaluate the association between MUFA intake and risk of gastric cancer in a hospital-based case–control study comprising 1182 incident cases of gastric cancer and 2965 controls in Vietnam.  \nMethods MUFA intake was quantified using a semi-quantitative validated food frequency questionnaire (FFQ) . We used an unconditional logistic regression model to calculate the odds ratios (ORs) and 95% confidence intervals (CIs) for the risk of gastric cancer in relation to MUFA intake.  \nResults Overall, there was an inverse association between MUFA intake and gastric cancer risk (ORper-SD increment = 0.75, 95% CI 0.67–0.84; Ptrend \u003C 0.001). Compared with the lowest quintile, the ORs (95% CIs) of gastric cancer for quintiles 2, 3, 4, and 5 of the MUFA intake were 0.86 (0.68–1.03), 0.65 (0.51–0.81), 0.53 (0.41–0.67) and 0.43 (0.33–0.57), respectively. A similar pattern was observed in both sexes and in individuals aged \u003C 60 years and those aged 60 years or older.  \nConclusions In summary, MUFA intake was associated with a reduced risk of gastric cancer in the Vietnamese population, regardless of sex or age. Our findings have great implications for gastric cancer prevention and control programs in lowmiddle-income countries and similar limited-resource settings.  \nKeywords Monounsaturated fatty acids · MUFA intake · Dietary · Gastric cancer risk · Case–control study · Vietnam  \nNgoan Tran Le, Yen Thi-Hai Pham contributed equally as first authors.  \nNgoan Tran Le and Hung N. Luu contributed equally as senior authors.  \n􀀍  \n1  \n2  \n3  \n4  \nHung N. Luu  \n[hluu2@houstonmethodist.org](hluu2@houstonmethodist.org)  \nNgoan Tran Le  \n[letranngoan@duytan.edu.vn](letranngoan@duytan.edu.vn)  \nInstitute of Research and Development, Duy Tan University, Da Nang, Vietnam  \nUniversity of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, PA, USA  \nDepartment of Epidemiology, School of Public Health, University of Pittsburgh, Pittsburgh, PA, USA  \nDr. Mary and Ron Neal Cancer Center, Houston Methodist Research Institute, Houston Methodist Hospital, 6670 Bertner Avenue, Room R9-213, Houston, TX 77030, USA  \n5 Laboratory of Embryology and Genetics of Human Malformation, Imagine Institute, INSERM UM`R, Paris, France  \n6 School of Medicine, International University of Health and Welfare, Narita City, Japan  \n7 Division of Epidemiology, Department of Medicine, Vanderbilt Epidemiology Center, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA  \n8 Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, USA  \nIntroduction  \nGastric cancer is one of the leading cancer incidence and mortality worldwide, with annual 968,000 new cases and close to 660,000 deaths [1] . In the United States, approximately 27,000 new cases of and 11,000 deaths from gastric cancer are expected in 2024 [2] . In Vietnam, gastric cancer is considered one of the leading malignancies, ranking 4th in incidence and 3rd in mortality [3] . While there have been many advancements in early detection and treatment, gast","cbCaikdyUkLg8j25","https://ap.wps.com/l/cbCaikdyUkLg8j25","pdf",1112961,12,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusions\n# Introduction\n## Gastric cancer burden and risk factors\n## MUFA sources and proposed health effects\n## Prior evidence from observational studies","[{\"question\":\"What is the main focus of this study?\",\"answer\":\"The study evaluates the association between dietary monounsaturated fatty acid (MUFA) intake and the risk of gastric cancer in Vietnam.\"},{\"question\":\"How was MUFA intake measured?\",\"answer\":\"MUFA intake was quantified using a validated semi-quantitative food frequency questionnaire (FFQ).\"},{\"question\":\"What were the key findings regarding gastric cancer risk?\",\"answer\":\"Higher MUFA intake showed an inverse association with gastric cancer risk, with results consistent across sexes and age groups (\\u003c60 and ≥60 years).\"}]","Dietary Monounsaturated Fatty Acids in Relation to Risk of Gastric Cancer | PDF",1790192882]