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Emerging evidence suggests dietary interventions may play a meaningful role alongside pharmacy and surgery.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"What is the current limitation of standard PD treatments?",{"text":68,"@type":64},"Current treatments mainly ameliorate or alleviate partial symptoms and signs in early and mid-stages. No existing medicine or surgery can prevent PD progression or cure the disease.",{"name":70,"@type":61,"acceptedAnswer":71},"Which diet-related components does the review focus on?",{"text":72,"@type":64},"The review focuses on polyphenols, fatty acids, vitamins, and dietary patterns as diet interventions relevant to prevention and treatment of PD.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},407401,1790760562,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,110,115,120,123,127],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":107,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":108,"slug":109},7,40,"healthcare",{"id":111,"doc_module":4,"doc_module_name":25,"category_name":112,"show_sort_weight":113,"slug":114},8,"Research & Report",30,"research-report",{"id":116,"doc_module":4,"doc_module_name":25,"category_name":117,"show_sort_weight":118,"slug":119},9,"Religion & Spirituality",20,"religion-spirituality",{"id":118,"doc_module":4,"doc_module_name":25,"category_name":121,"show_sort_weight":118,"slug":122},"World Cup","world-cup",{"id":124,"doc_module":4,"doc_module_name":25,"category_name":125,"show_sort_weight":124,"slug":126},10,"Lifestyle","lifestyle",{"id":128,"doc_module":4,"doc_module_name":25,"category_name":129,"show_sort_weight":97,"slug":130},19,"General","general",{"code":4,"msg":82,"data":132},{"doc_id":79,"user_id":133,"nickname":42,"user_avatar":134,"doc_module":4,"category_id":107,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":140,"language":141,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":12,"update_tm":145,"read_time":146,"preview_page_count":4},13056703020460,"https://ap-avatar.wpscdn.com/avatar/be000253dac470eee5d?_k=1778207105932848923","OPEN ACCESS  \nEDITED BY  \nIngrid Lofgren,  \nUniversity of Rhode Island, United States  \nREVIEWED BY  \nSergio A. Castillo-Torres,  \nUniversidad Autónoma de Nuevo León, Mexico  \nLaura Beth McIntire,  \nNewYork-Presbyterian, United States  \n*CORRESPONDENCE  \nRenshi Xu  \n [xurenshi@ncu.edu.cn](xurenshi@ncu.edu.cn)  \n†These authors have contributed equally to this work  \nRECEIVED 07 March 2025  \nREVISED 16 November 2025  \nACCEPTED 28 November 2025  \nPUBLISHED 17 December 2025  \nCITATION  \nChen W, Fan T and Xu R (2025) Diet for the prevention and treatment of Parkinson’s disease.  \nFront. Nutr. 12:1587246 .  \ndoi: 10.3389/fnut.2025.1587246  \nCOPYRIGHT  \n© 2025 Chen, Fan and Xu. This is an  \nopen-access article distributed under the terms of the Creative Commons Attribution License (CC BY) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.  \nTYPE Review  \nPUBLISHED 17 December 2025 DOI 10.3389/fnut.2025.1587246  \nDiet for the prevention and treatment of Parkinson’s disease  \nWenzhi Chen1†, Ting Fan 1,2† and Renshi Xu1,2*  \n1Department of Neurology, Jiangxi Provincial People’s Hospital, The Clinical College of Nanchang Medical College, The First Affiliated Hospital of Nanchang Medical College, Xiangya Hospital of Center South University, Jiangxi Hospital and National Regional Center for Neurological Disease, Nanchang, Jiangxi, China, 2School of Clinical Medicine, Jiangxi University of Traditional Chinese Medicine, Nanchang, China  \nParkinson’s disease (PD) is a common degenerative disease of the central nervous system with a variety of non-motor symptoms, in addition to the typical motor symptoms, which seriously affect the physical and mental health of patients, as well as their quality of life. All current treatment measures for PD only ameliorate and alleviate partial symptoms and signs in the early and middle stages. To date, no medicine or surgery can prevent PD progression. The search for preventive measures to treat and prevent PD is currently a research priority. Based on current related studies and investigations, diet interventions have now been found to play important roles in the treatment and prevention of PD. This article reviews recent research advances in diet in terms of polyphenols, fatty acids, vitamins, and dietary patterns for the prevention and treatment of PD.  \nKEYWORDS  \nParkinson’s disease, polyphenols, fatty acids, vitamins, dietary pattern  \n1 Introduction  \nParkinson’s disease (PD) is a neurodegenerative disease commonly present in middle-aged and elderly populations, with insidious onset and progressive exacerbation. Its clinical manifestations include motor symptoms, such as bradykinesia, resting tremor, myotonia, and postural balance disorders, and non-motor symptoms, such as hyposmia, sleep disturbance, constipation, and mental and cognitive impairment ( 1). The main pathological features of PDare the absence of dopaminergic neurons in the dense substantia nigra and accumulation of toxic Lewy bodies in the cytoplasm of neurons ( 1–3) .  \nAt present, the treatment of PD only ameliorates and alleviates the partial symptoms and signs at the early and mid-stages, cannot prevent and squelch the pathological lesions of PD, and cannot reverse and stop the progression of PD (2) . The current major treatment of PD supplies the deficiency of dopaminergic neurotransmitters and/or reduces the degradation of dopaminergic neurotransmitters in the synaptic gap of the striatum, or the use of dopaminergic agonists to model dopaminergic neurotransmitters to stimulate the dopaminergic receptor to relieve the symptoms and signs, mainly consisting of compound levodopa agents (dopaminergic neurotransmitter supplemental drugs), monoamine oxida","cbCaigGhGPQM3x0o","https://ap.wps.com/l/cbCaigGhGPQM3x0o","pdf",1628891,14,"English","# 1 Introduction\n# 2 Polyphenols","[{\"question\":\"Why is diet considered important for preventing and treating Parkinson’s disease?\",\"answer\":\"Diet is considered a potential environmental factor in PD development and progression. Emerging evidence suggests dietary interventions may play a meaningful role alongside pharmacy and surgery.\"},{\"question\":\"What is the current limitation of standard PD treatments?\",\"answer\":\"Current treatments mainly ameliorate or alleviate partial symptoms and signs in early and mid-stages. No existing medicine or surgery can prevent PD progression or cure the disease.\"},{\"question\":\"Which diet-related components does the review focus on?\",\"answer\":\"The review focuses on polyphenols, fatty acids, vitamins, and dietary patterns as diet interventions relevant to prevention and treatment of PD.\"}]","Diet for the prevention and treatment of Parkinson’s disease | PDF",1790573645,35]