[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-333465-105":59,"doc-detail-333465-en":135},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":128,"head_meta":130,"extra_data":132,"updated_unix":134},105,"en","diagnostic-accuracy-of-high-frequency-ultrasound-for-cutaneous-neoplasms-a-narrative-review-of-the-literature","Diagnostic accuracy of high-frequency ultrasound for cutaneous neoplasms - a narrative review of the literature","","High-frequency ultrasound is used to visualize depth and vascularization of cutaneous neoplasms, yet robust evidence on diagnostic accuracy has not been consolidated. A narrative review of PubMed literature assessed how ultrasound findings correspond with histopathologic and dermoscopic features. Studies were grouped into melanocytic, keratinocytic/epidermal, appendageal, and soft tissue/neural neoplasms. Ultrasound and histopathology showed strong correlation for tumor depth, while morphological correlations were most evident in soft tissue/neural neoplasms. Literature remains limited overall, requiring further studies across dermatologic conditions.",{"@graph":69,"@context":127},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/diagnostic-accuracy-of-high-frequency-ultrasound-for-cutaneous-neoplasms-a-narrative-review-of-the-literature/333465/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/diagnostic-accuracy-of-high-frequency-ultrasound-for-cutaneous-neoplasms-a-narrative-review-of-the-literature/333465.png","ImageObject",300,407,{"name":92,"@type":93},"Hazel","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-03","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",14,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119,123],{"name":110,"@type":111,"acceptedAnswer":112},"What diagnostic question does this narrative review address?","Question",{"text":113,"@type":114},"It evaluates the diagnostic accuracy of high-frequency ultrasound (HFUS) for cutaneous neoplasms by examining correlations between ultrasound findings and histopathologic/dermoscopic findings.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How were the reviewed articles categorized?",{"text":118,"@type":114},"They were divided into four categories based on World Health Organization classification: melanocytic, keratinocytic/epidermal, appendageal, and soft tissue/neural neoplasms.",{"name":120,"@type":111,"acceptedAnswer":121},"What did the review find about ultrasound versus histopathology?",{"text":122,"@type":114},"Ultrasound findings were strongly correlated with histopathologic findings regarding the depth of a cutaneous neoplasm, while morphological characteristics correlated primarily in soft tissue/neural neoplasms.",{"name":124,"@type":111,"acceptedAnswer":125},"What limitations and future research needs are highlighted?",{"text":126,"@type":114},"The review notes a paucity of literature on the correlation between HFUS and histopathology, calling for further studies to investigate these relationships across various dermatologic conditions.","https://schema.org",{"og:url":83,"og:type":129,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":131,"canonical":83},"index,follow",{"doc_id":133,"site_id":62},333465,1790218672,{"code":4,"msg":5,"data":136},{"doc_id":133,"user_id":137,"nickname":92,"user_avatar":138,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":139,"file_id":140,"file_url":141,"file_type":142,"file_size":143,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":144,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":145,"faqs":146,"seo_title":147,"seo_description":67,"update_tm":148,"read_time":149,"preview_page_count":4},137441390410,"https://ap-avatar.wpscdn.com/avatar/2000252f4ab5702993?_k=1776741390130283984","Archives of Dermatological Research (2024) 316:419 [https://doi.org/10.1007/s00403-024-03179-7](https://doi.org/10.1007/s00403-024-03179-7)  \nREVIEW  \nDiagnostic accuracy of high-frequency ultrasound for cutaneous neoplasms: a narrative review of the literature  \nCatherine Grace P. Hobayan1 · Ashley N. Gray2 · Margo F. Waters1 · Layna A. Mager1 · Sonja Kobayashi1 ·  \nEllen W. Essien1 · Catherine A. Ulman2 · Benjamin H. Kaffenberger2  \nReceived: 4 March 2024 / Revised: 7 June 2024 / Accepted: 8 June 2024 / Published online: 21 June 2024 © The Author(s) 2024  \nAbstract  \nHigh-frequency ultrasound has been used to visualize depth and vascularization of cutaneous neoplasms, but little has been synthesized as a review for a robust level of evidence about the diagnostic accuracy of high-frequency ultrasound in dermatology. A narrative review of the PubMed database was performed to establish the correlation between ultrasound findings and histopathologic/dermoscopic findings for cutaneous neoplasms. Articles were divided into the following four categories: melanocytic, keratinocytic/epidermal, appendageal, and soft tissue/neural neoplasms. Review of the literature revealed that ultrasound findings and histopathology findings were strongly correlated regarding the depth of a cutaneous neoplasm. Morphological characteristics were correlated primarily in soft tissue/neural neoplasms. Overall, there is a paucity of literature on the correlation between high-frequency ultrasound and histopathology of cutaneous neoplasms. Further studies are needed to investigate this correlation in various dermatologic conditions.  \nKeywords Cutaneous neoplasm · General dermatology · Medical dermatology · Oncology · Pathology · Ultrasound  \nIntroduction  \nHigh frequency ultrasound (HFUS) has been used in clinical dermatology to visualize the physical characteristics of cutaneous neoplasms, such as depth and vascularization [1, 2]. Despite the known clinical utility of HFUS, dermoscopy followed by histopathologic diagnosis of biopsy specimens remains the gold standard for dermatologic diagnosis [1, 2] . HFUS is used as a supplementary imaging modality in conjunction with current clinical practice to noninvasively visualize deeper skin tissue at bedside, similar to how dermoscopy is used for noninvasive microscopic evaluation of lesions at bedside [1, 2] . To ensure that HFUS provides accurate visual information regarding dermatologic conditions, it is critical to elucidate the correlations between HFUS and histopathologic appearance. Thus, the purpose  \n􀀍 Benjamin H. Kaffenberger [Benjamin.Kaffenberger@osumc.edu](Benjamin.Kaffenberger@osumc.edu)  \n1 The Ohio State University College of Medicine, Columbus, OH, USA  \n2 Department of Dermatology, The Ohio State University, 540 Officecenter Place, Suite 240, Columbus, OH 43230, USA  \nof this narrative review is to demonstrate the similarities between HFUS and histopathologic findings for cutaneous neoplasms.  \nMaterials and methods  \nThe authors performed a search of the PubMed database with a combination of Medical Subject Headings (MeSH) and controlled terms in April 2024; no filters on language or publication date were placed. Exclusion criteria included the following: articles that did not directly make comparisons between HFUS and histopathology/dermoscopy, articles that focused on lymph node evaluation, articles discussing cutaneous metastases of primary visceral cancers, and articles that primarily featured the use of ultrasound for internal organs or did not mention ultrasound at all. No language or time filters were placed on the search query. The search query returned 495 results. 62 duplicate articles were removed. 238 articles were excluded during title and abstract screening, and 63 articles were excluded during full text screening. A total of 132 articles are included in in this narrative review. Articles were divided into four categories based on World Health Organization classification  \nof cut","cbCaibrKlCDsXYli","https://ap.wps.com/l/cbCaibrKlCDsXYli","pdf",864343,"English","# Abstract\n# Introduction\n# Materials and methods\n# Results\n## Melanocytic cutaneous neoplasms\n## Cutaneous neoplasm categories (WHO classification)\n# Table 1: Reviewed articles and key points","[{\"question\":\"What diagnostic question does this narrative review address?\",\"answer\":\"It evaluates the diagnostic accuracy of high-frequency ultrasound (HFUS) for cutaneous neoplasms by examining correlations between ultrasound findings and histopathologic/dermoscopic findings.\"},{\"question\":\"How were the reviewed articles categorized?\",\"answer\":\"They were divided into four categories based on World Health Organization classification: melanocytic, keratinocytic/epidermal, appendageal, and soft tissue/neural neoplasms.\"},{\"question\":\"What did the review find about ultrasound versus histopathology?\",\"answer\":\"Ultrasound findings were strongly correlated with histopathologic findings regarding the depth of a cutaneous neoplasm, while morphological characteristics correlated primarily in soft tissue/neural neoplasms.\"},{\"question\":\"What limitations and future research needs are highlighted?\",\"answer\":\"The review notes a paucity of literature on the correlation between HFUS and histopathology, calling for further studies to investigate these relationships across various dermatologic conditions.\"}]","Diagnostic accuracy of high-frequency ultrasound for cutaneous neoplasms - a narrative review of the literature | PDF",1790002590,23]