[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-406829-105":59,"doc-detail-406829-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","developmental-venous-anomalies-and-cerebral-cavernous-malformations-partners-in-crime-review","Developmental venous anomalies and cerebral cavernous malformations: Partners in crime - Review","","Developmental venous anomalies (DVAs) are benign congenital veins that channel normal brain venous drainage into a single outlet, while cerebral cavernous malformations (CMs) consist of thin-walled capillary cavities prone to bleeding. When DVAs and CMs coexist, altered venous pressure and flow may contribute to CM formation or rupture. Identifying a DVA adjacent to an otherwise unexplained intracerebral hemorrhage can therefore suggest an occult CM and guide accurate, timely diagnosis and targeted management.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/developmental-venous-anomalies-and-cerebral-cavernous-malformations-partners-in-crime-review/406829/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/developmental-venous-anomalies-and-cerebral-cavernous-malformations-partners-in-crime-review/406829.png","ImageObject",300,407,{"name":92,"@type":93},"Alexandar","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-03","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What are developmental venous anomalies (DVAs)?","Question",{"text":113,"@type":114},"DVAs are benign congenital veins that collect normal brain venous drainage into a single outlet.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What are cerebral cavernous malformations (CMs)?",{"text":118,"@type":114},"CMs are clusters of thin-walled capillary cavities that are prone to bleeding.",{"name":120,"@type":111,"acceptedAnswer":121},"How does the coexistence of DVAs and CMs influence diagnosis and management?",{"text":122,"@type":114},"An altered venous pressure and flow associated with a DVA may promote CM formation or rupture, so a DVA next to an unexplained intracerebral hemorrhage can indicate an occult CM and support accurate, timely diagnosis and appropriately targeted management.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},406829,1790625050,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":145,"read_time":146,"preview_page_count":4},962090768658,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","| W | J | R | World Journal of\u003Cbr>Radiology |\n| --- | --- | --- | --- |\n\nSubmit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Radiol 2025 December 28; 17(12): 114595  \nDOI: 10.4329/wjr.v17.i12.114595 ISSN 1949-8470 (online)  \nREVIEW  \nDevelopmental venous anomalies and cerebral cavernous malformations: Partners in crime  \nNikolaos-Achilleas Arkoudis, Manos Siderakis, Ilianna Tsetsou, Evgenia Efthymiou, George Triantafyllou, Dimitrios Chalmoukis, Anastasia Karachaliou, Andreas Papadopoulos, Spyridon Prountzos, Ornella Moschovaki-Zeiger, Nikolaos Gouliopoulos, Olympia Papakonstantinou, Dimitrios Filippiadis, Georgios Velonakis  \nSpecialty type: Radiology, nuclear medicine and medical imaging  \nProvenance and peer review:  \nInvited article; Externally peer reviewed.  \nPeer-review model: Single blind  \nPeer-review report’s classification Scientific Quality: Grade B  \nNovelty: Grade C  \nCreativity or Innovation: Grade C  \nScientific Significance: Grade B  \nP-Reviewer: Sade R, MD, Associate Professor, Türkiye  \nReceived: September 24, 2025  \nRevised: October 13, 2025  \nAccepted: November 3, 2025  \nPublished online: December 28, 2025  \nProcessing time: 93 Days and 22.4 Hours  \nNikolaos-Achilleas Arkoudis, Evgenia Efthymiou, Georgios Velonakis, Research Unit of Radiology and Medical Imaging, National and Kapodistrian University of Athens, Athens 11528, Greece  \nNikolaos-Achilleas Arkoudis, Evgenia Efthymiou, Dimitrios Chalmoukis, Anastasia Karachaliou, Andreas Papadopoulos, Spyridon Prountzos, Ornella Moschovaki-Zeiger, Olympia Papakonstantinou, Dimitrios Filippiadis, Georgios Velonakis, The Second Department of Radiology, General University Hospital “Attikon”, National and Kapodistrian University of Athens, Athens 12462, Greece  \nManos Siderakis, Department of Radiology, Agios Savas Anticancer Hospital, Athens 11522, Greece  \nIlianna Tsetsou, Department of Imaging and Interventional Radiology,“Sotiria” General and Chest Diseases Hospital of Athens, Athens 11527, Greece  \nGeorge Triantafyllou, Department of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, Athens 11527, Attikí, Greece  \nNikolaos Gouliopoulos, Moorfields Eye Hospital, London 162, London, United Kingdom  \nCorresponding author: Nikolaos-Achilleas Arkoudis, MD, PhD, Consultant, Lecturer, Researcher, Research Unit of Radiology and Medical Imaging, National and Kapodistrian University of Athens, 19 Papadiamantopoulou Street, Athens 11528, Greece.  \n[nick.arkoudis@gmail.com](nick.arkoudis@gmail.com)  \nAbstract  \nDevelopmental venous anomalies (DVAs) are benign congenital veins that collect normal brain drainage into a single outlet. Cerebral cavernous malformations (CMs) are clusters of thin-walled capillary cavities prone to bleeding. When both lesions coexist, the DVA’s altered venous pressure and flow can promote CM formation or rupture. Detecting a DVA abutting an otherwise unexplained intracerebral hemorrhage can therefore raise suspicion of an occult CM as a likely cause, a clue which may be invaluable for daily clinical practice. The main focus of this review is to acknowledge the hallmark imaging appearances of DVAs and  \n WJR  [https://www.wjgnet.com](https://www.wjgnet.com) 1 December 28, 2025  Volume 17  Issue 12   \nArkoudis NA et al. DVAs and CMs: Partners in crime  \nCMs, as well as their coexistence, explore the clinical consequences of mixed lesions, and emphasize that recognizing their partnership is vital for an accurate, timely diagnosis and appropriately targeted management.  \nKey Words: Vascular malformations; Developmental venous anomaly; Cavernous malformation; Brain magnetic resonance imaging; Central nervous system; Neuroimaging; Cerebral venous circulation; Neuroradiology; Radiology review  \n©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.  \nCore Tip: When developmental venous anomalies (DVAs) and cerebral cavernous malfor","cbCaib8MJZzvDTZg","https://ap.wps.com/l/cbCaib8MJZzvDTZg","pdf",15777303,22,"English","# Abstract\n# Core Tip\n# Introduction\n## Definition","[{\"question\":\"What are developmental venous anomalies (DVAs)?\",\"answer\":\"DVAs are benign congenital veins that collect normal brain venous drainage into a single outlet.\"},{\"question\":\"What are cerebral cavernous malformations (CMs)?\",\"answer\":\"CMs are clusters of thin-walled capillary cavities that are prone to bleeding.\"},{\"question\":\"How does the coexistence of DVAs and CMs influence diagnosis and management?\",\"answer\":\"An altered venous pressure and flow associated with a DVA may promote CM formation or rupture, so a DVA next to an unexplained intracerebral hemorrhage can indicate an occult CM and support accurate, timely diagnosis and appropriately targeted management.\"}]","Developmental venous anomalies and cerebral cavernous malformations: Partners in crime - Review | PDF",1790568225,55]