[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-31480":3,"doc-seo-31480":27},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"file_id":15,"file_url":16,"file_type":17,"file_size":18,"view_count":4,"is_deleted":4,"is_public":19,"is_downloadable":19,"audit_status":19,"page_count":20,"language":21,"language_code":22,"table_of_contents":23,"faqs":24,"seo_title":13,"seo_description":14,"update_tm":25,"read_time":26},31480,137441390410,"Hazel","https://ap-avatar.wpscdn.com/avatar/2000252f4ab5702993?_k=1776741390130283984",8,"Research & Report","Design of Metal-Organic Frameworks for pH-Responsive Drug Delivery","Metal-Organic Frameworks (MOFs) attract strong attention in nanoscience and biomedical applications including drug delivery systems (DDS), biomedical imaging (BI), and photodynamic therapy (PDT). As emerging porous materials, MOFs offer high surface area, controllable particle size, and good biocompatibility, with design flexibility enabled by tunable organic and inorganic components. This review consolidates MOF design and synthesis strategies and summarizes recent advances in DDS, BI, and PDT, and further outlines prospects and future challenges.","cbCaiesPW8Fv73hM","https://ap.wps.com/l/cbCaiesPW8Fv73hM","pdf",7036980,1,22,"English","en","# Introduction\n## MOF/PCP structures and components\n## Ligand types and tunability\n## Common MOF families and reported diversity\n# Applications Overview\n## MOFs in DDS, BI, and PDT\n## Key material properties guiding performance\n# Design, Synthesis Strategies and Future Directions","[{\"question\":\"What biomedical applications are highlighted for metal-organic frameworks (MOFs)?\",\"answer\":\"MOFs are discussed for drug delivery systems (DDS), biomedical imaging (BI), and photodynamic therapy (PDT).\"},{\"question\":\"Why are MOFs considered suitable as drug delivery vehicles?\",\"answer\":\"MOFs combine high surface area, controllable particle size, good biocompatibility, and design flexibility of organic/inorganic components, enabling functional tuning for delivery uses.\"},{\"question\":\"How do organic ligands influence MOF structure and properties?\",\"answer\":\"Ligands with flexible spacers tune the relative distance and direction between coordination points, while non-flexible spacers induce bending and rotation, both allowing extensive variation in composition, dimensionality, porosity, and surface characteristics.\"}]",1779570092,55,{"code":4,"msg":28,"data":29},"ok",{"site_id":30,"language":22,"slug":31,"title":13,"keywords":32,"description":14,"schema_data":33,"social_meta":84,"head_meta":86,"extra_data":88,"updated_unix":25},105,"design-of-metal-organic-frameworks-for-ph-responsive-drug-delivery","",{"@graph":34,"@context":83},[35,52,66],{"@type":36,"itemListElement":37},"BreadcrumbList",[38,42,46,49],{"item":39,"name":40,"@type":41,"position":19},"https://docshare.wps.com","Home","ListItem",{"item":43,"name":44,"@type":41,"position":45},"https://docshare.wps.com/document/","Document",2,{"item":47,"name":12,"@type":41,"position":48},"https://docshare.wps.com/document/research-report/",3,{"item":50,"name":13,"@type":41,"position":51},"https://docshare.wps.com/document/design-of-metal-organic-frameworks-for-ph-responsive-drug-delivery/31480/",4,{"url":50,"name":13,"@type":53,"author":54,"headline":13,"publisher":56,"fileFormat":59,"description":14,"dateModified":60,"datePublished":60,"encodingFormat":59,"isAccessibleForFree":61,"interactionStatistic":62},"DigitalDocument",{"name":9,"@type":55},"Person",{"url":39,"name":57,"@type":58},"DocShare","Organization","application/pdf","2026-05-23",true,{"@type":63,"interactionType":64,"userInteractionCount":4},"InteractionCounter",{"@type":65},"ViewAction",{"@type":67,"mainEntity":68},"FAQPage",[69,75,79],{"name":70,"@type":71,"acceptedAnswer":72},"What biomedical applications are highlighted for metal-organic frameworks (MOFs)?","Question",{"text":73,"@type":74},"MOFs are discussed for drug delivery systems (DDS), biomedical imaging (BI), and photodynamic therapy (PDT).","Answer",{"name":76,"@type":71,"acceptedAnswer":77},"Why are MOFs considered suitable as drug delivery vehicles?",{"text":78,"@type":74},"MOFs combine high surface area, controllable particle size, good biocompatibility, and design flexibility of organic/inorganic components, enabling functional tuning for delivery uses.",{"name":80,"@type":71,"acceptedAnswer":81},"How do organic ligands influence MOF structure and properties?",{"text":82,"@type":74},"Ligands with flexible spacers tune the relative distance and direction between coordination points, while non-flexible spacers induce bending and rotation, both allowing extensive variation in composition, dimensionality, porosity, and surface characteristics.","https://schema.org",{"og:url":50,"og:type":85,"og:title":13,"og:site_name":57,"og:description":14},"article",{"robots":87,"canonical":50},"index,follow",{"doc_id":7,"site_id":30}]