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Benign lesions can imitate cancer on imaging and early needle biopsies, complicating treatment planning. The report presents a rare breast cylindroma initially interpreted as invasive ductal carcinoma with basaloid features after core biopsy, prompting excision and axillary sentinel node dissection. Final pathology confirmed cylindroma with negative sentinel nodes, emphasizing its inclusion in the differential for breast cancer.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/cylindroma-of-the-breast-differential-diagnosis-for-breast-cancer-on-core-biopsies-case-report-and-review-of-literature/332074/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/cylindroma-of-the-breast-differential-diagnosis-for-breast-cancer-on-core-biopsies-case-report-and-review-of-literature/332074.png","ImageObject",300,407,{"name":92,"@type":93},"Eliana","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",13,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why can cylindroma be mistaken for breast cancer on imaging and core biopsy?","Question",{"text":113,"@type":114},"Benign breast pathology can mimic breast cancers on imaging and initial needle biopsies. In this case, imaging and core biopsy findings were initially concerning for breast cancer.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What final diagnosis and key pathology findings were reported after excision?",{"text":118,"@type":114},"Final pathology identified a 2.4-cm cylindroma with margins of at least 5 mm and atypical ductal hyperplasia. Sentinel lymph nodes were negative.",{"name":120,"@type":111,"acceptedAnswer":121},"What treatment approach is described for cylindroma of the breast?",{"text":122,"@type":114},"Treatment of breast cylindromas is excision. The review emphasizes that sentinel lymph node dissection is not indicated and adjuvant therapies are not needed when cylindroma is identified.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},332074,1790431995,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":81,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":39},4398048949847,"https://ap-avatar.wpscdn.com/avatar/400002536579ef2da7f?_k=1778318612642679267","Cylindroma of the Breast: A Rare Differential for Breast Cancer on Core Biopsies, Case Report and Review of Literature  \nDre Steinwehr, MD 1, Toshi Ghosh, MD2, and Michael Bouton, MD 1  \nJournal of Investigative Medicine High Impact Case Reports  \nVolume 12: 1–3  \n© 2024 American Federation for Medical Research  \nDOI: 10. 1177/23247096241246627 [journals.sagepub.com/home/hic](journals.sagepub.com/home/hic)  \nAbstract  \nBreast cancers of either ductal or lobular pathology make up the vast majority of breast malignancies. Other cancers occur rarely in the breast. Benign pathology can at times mimic breast cancers on imaging and initial needle biopsies. We report a rare breast pathology of cylindroma. Cylindromas are usually benign, rare dermatologic lesions most commonly associated with head or neck locations. They more commonly occur as sporadic and solitary masses. Less commonly is an autosomaldominant multi-centric form of this disease. Malignant cylindromas are very rare. We present a patient with findings of a cylindroma of the breast after excision. This was initially felt to be concerning for breast cancer on imaging and core biopsy. Treatment of cylindromas of the breast is excision. Sentinel lymph node dissection is not indicated, nor are adjuvant therapies when identified in the breast. This lesion needs to be included in the differential diagnosis for breast cancer. If cylindromas can be accurately diagnosed preoperatively, this would negate the need for consideration of axillary nodal surgery and adjuvant therapies.  \nKeywords  \nbreast cancer, cylindroma, adenoid cystic carcinoma, benign breast pathology, rare breast pathology  \nNational American College of Physicians April 2023 “Rare breast pathology with cylindroma of breast on surgical resection.” Dre Steinwehr, Toshi Ghosh, and Michael Bouton. National ACP Poster Contest. San Diego, CA. Southeastern Surgical Congress February 2023  \n“Rare breast pathology with cylindroma of breast on surgical resection.” Dre Steinwehr, Toshi Ghosh, and Michael Bouton. National ACP Poster Contest. San Diego, CA.  \nCase Report  \nThe patient is a 79-year-old woman who fell while walking up a flight of stairs. This resulted in an injury to the chest. Evaluation, including a chest computed tomography scan, revealed a mass in the left breast (Figure 1) . Subsequent breast-specific imaging resulted in multiple left breast core biopsies (Figure 2) . Two areas revealed fibroadenoid changes and were concordant. A 1.5-cm, upper inner left breast mass was interpreted to be an invasive ductal carcinoma with basaloid features on core biopsy. This was estrogen receptor low positive (1%), progesterone receptor negative, and human epidermal growth factor receptor 2 negative. The pathologic differential on the lesion on core  \nbiopsy included possible adenoid cystic carcinoma. She has a family history of breast cancer in her daughter. Co-morbidities included hypertension and morbid obesity. Her performance status was good.  \nWith multidisciplinary planning, a left breast needle localization lumpectomy and axillary sentinel lymph node dissection were performed due to the initial diagnosis of cancer 58 days following initial imaging. The surgical pathology had 2 negative sentinel nodes. The final pathology on the breast mass revealed a 2.4-cm cylindroma, margins 5 mm or greater, as well as atypical ductal hyperplasia (size larger than initial imaging with time to surgery) .  \n1 University of North Dakota, Fargo, USA 2Sanford Medical Center, Fargo, ND, USA  \nDre Steinwehr and Michael Bouton are also affiliated to Sanford Medical Center, Fargo, ND, USA  \nReceived November 11, 2023. Revised March 6, 2024. Accepted March 22, 2024.  \nCorresponding Author:  \nDre Steinwehr, MD, Department of Surgery, University of North Dakota, 1919 N Elm St., Fargo, ND 58102, USA. [Email: Dre.steinwehr@sanfordhealth.org](Email: Dre.steinwehr@sanfordhealth.org)  \nCreative Commons Non Commercial CC BY-NC: This article is di","cbCaitdOApPZOmsI","https://ap.wps.com/l/cbCaitdOApPZOmsI","pdf",1259483,"English","# Abstract\n# Case Report\n## Initial presentation and imaging\n## Core biopsy findings and treatment\n## Surgical pathology and final diagnosis\n# Pathology\n# Discussion","[{\"question\":\"Why can cylindroma be mistaken for breast cancer on imaging and core biopsy?\",\"answer\":\"Benign breast pathology can mimic breast cancers on imaging and initial needle biopsies. In this case, imaging and core biopsy findings were initially concerning for breast cancer.\"},{\"question\":\"What final diagnosis and key pathology findings were reported after excision?\",\"answer\":\"Final pathology identified a 2.4-cm cylindroma with margins of at least 5 mm and atypical ductal hyperplasia. Sentinel lymph nodes were negative.\"},{\"question\":\"What treatment approach is described for cylindroma of the breast?\",\"answer\":\"Treatment of breast cylindromas is excision. The review emphasizes that sentinel lymph node dissection is not indicated and adjuvant therapies are not needed when cylindroma is identified.\"}]","Cylindroma of the Breast - Differential Diagnosis for Breast Cancer on Core Biopsies - Case Report and Review of Literature | PDF",1789996629]