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This review summarizes transanal excision, transanal endoscopic microsurgery, and transanal minimally invasive surgery, emphasizing when proper diagnostics establish eligibility. Compared with total mesorectal excision, transanal excision shows fewer complications while achieving complete cancer tissue removal in suitable cases. Local excision can also support organ preservation when combined with neoadjuvant chemoradiotherapy, total neoadjuvant therapy, and immunotherapy.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/current-surgical-methods-in-local-rectal-excision-review-article/330959/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/current-surgical-methods-in-local-rectal-excision-review-article/330959.png","ImageObject",300,407,{"name":92,"@type":93},"Noah","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why are less invasive local excision methods becoming more accepted for rectal cancer?","Question",{"text":112,"@type":113},"Advances in surgical techniques have made transanal and local excision approaches less invasive. For strictly selected patients, these methods can be offered as primary curative treatment while reducing morbidity.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What are the key differences between transanal excision, TEM, and TAMIS?",{"text":117,"@type":113},"Transanal excision removes visible rectal lesions. TEM dilates the rectum mechanically and with air insufflation, then removes suspicious lesions under telescope vision. TAMIS combines TEM principles with single-incision laparoscopic surgery to reach difficult proximal rectal areas with laparoscopic instruments.",{"name":119,"@type":110,"acceptedAnswer":120},"When can transanal surgery be used in locally advanced rectal cancer?",{"text":121,"@type":113},"Transanal surgery may be offered as part of an organ preservation strategy for locally advanced disease when combined with other modalities such as neoadjuvant chemoradiotherapy, total neoadjuvant therapy, and immunotherapy.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},330959,1790098976,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145},8796095462418,"https://ap-avatar.wpscdn.com/avatar/80000253c1241d02b47?x-image-process=image/resize,m_fixed,w_180,h_180&k=1778826106357471780","Gastrointestinal Tumors  \nReview Article  \nGastrointest Tumors 2024;10:44–56 DOI: 10.1159/000538958  \nReceived: March 24, 2023  \nAccepted: April 10, 2024  \nPublished online: April 17, 2024  \nCurrent Surgical Methods in Local Rectal Excision  \nKristina Šemanjskia Karla Lužaićb Jure Brkić a  \naDepartment of Surgery, Clinical Hospital Sveti Duh, Zagreb, Croatia; bInstitute of Emergency Medicine of Sisak-Moslavina County, Sisak, Croatia  \nKeywords  \nRectal cancer · Local excision · Surgical techniques · Transanal surgery · Organ preservation  \nAbstract  \nBackground: The treatment of rectal cancer has evolved with the advancement of surgical techniques. Less invasive approaches are becoming more accepted as the primary treatment method. Summary: Such methods as transanal excision, transanal endoscopic microsurgery, and transanal minimally invasive surgery can reduce morbidity and mortality rates. However, not all patients are suitable candidates for these procedures, and proper diagnostics are necessary to establish indications. Compared to total mesorectal excision, transanal excision techniques have been shown to have fewer complications and comorbidities while still being able to remove cancerous tissue entirely. Transanal excision is the simplest method, where the operator removes visible rectal lesions. The basic principle of transanal endoscopic microsurgery is to dilate the rectum mechanically and by air insufﬂation and then use special surgical instruments to remove suspicious lesions under the vision of a telescope. Transanal minimally invasive surgery combines transanal endoscopic microsurgery and singleincision laparoscopic surgery, making the hard-to-reach proximal rectum accessible to classic laparoscopic instruments. Key Message: Local excision techniques, when used as a monotherapy for treating patients with rectal cancer,  \nhave established themselves as a curative and less radical treatment for strictly selected patients with early rectal carcinoma, leading to improved quality of life. When combined with other modalities such as neoadjuvant chemoradiotherapy, total neoadjuvant therapy, and immunotherapy, transanal surgery can be offered to patients with locally advanced rectal cancer as part of the organ preservation strategy. This review will discuss the patient selection and technical aspects of transanal surgery, showcasing its current role in treating rectal carcinoma.  \n© 2024 The Author(s) .  \nPublished by S. Karger AG, Basel  \nIntroduction  \nAlthough colon and rectal cancer incidence has been dropping since the mid-1980s, colorectal cancer (CRC) is still the third most diagnosed cancer worldwide [1] . Rectal carcinoma (colon cancer within 15 cm from the anal verge) affects approximately 737,000 new patients per year worldwide [2] . The incidence of CRC is highly associated with screening programs. Studies have shown that the incidence has been decreasing in countries with long-standing faecal testing and screening colonoscopy programs and increasing mainly in countries with no screening programs available [3, 4] . Also, because of screening and timely diagnosis, the percentage of early rectal carcinoma is increasing; another fact is that CRC is  \n[karger@karger.com](karger@karger.com)[ ](karger@karger.com)[www.karger.com/gat](www.karger.com/gat)  \n© 2024 The Author(s) .  \nPublished by S. Karger AG, Basel  \nThis article is licensed under the Creative Commons AttributionNonCommercial4.0International License(CC BY-NC)([http://www](http://www). [karger.com/Services/OpenAccessLicense](karger.com/Services/OpenAccessLicense)). Usage and distribution for commercial purposes requires written permission.  \nCorrespondence to:  \nKristina Šemanjski, [ksemanj](ksemanj@ gmail.com)[@](ksemanj@ gmail.com)[ gmail.com](ksemanj@ gmail.com)  \nnow more diagnosed in younger people, demanding the balance between good curative oncological outcomes and the bad functional outcomes caused by overtreatment.  \nBefore and at the beginning","cbCaiu7vjRre8BgK","https://ap.wps.com/l/cbCaiu7vjRre8BgK","pdf",589059,13,"English","# Introduction\n## Trends in colorectal and rectal cancer incidence\n## Evolution of standard surgical approaches\n## Emergence and technological development of transanal surgery\n# Current Surgical Methods in Local Rectal Excision\n## Transanal excision\n## Transanal endoscopic microsurgery\n## Transanal minimally invasive surgery (TAMIS)\n# Patient Selection and Indications\n## Diagnostic requirements for candidacy\n# Technical Aspects and Role in Multimodal Therapy\n## Curative monotherapy in early disease\n## Integration with neoadjuvant/adjuvant modalities","[{\"question\":\"Why are less invasive local excision methods becoming more accepted for rectal cancer?\",\"answer\":\"Advances in surgical techniques have made transanal and local excision approaches less invasive. For strictly selected patients, these methods can be offered as primary curative treatment while reducing morbidity.\"},{\"question\":\"What are the key differences between transanal excision, TEM, and TAMIS?\",\"answer\":\"Transanal excision removes visible rectal lesions. TEM dilates the rectum mechanically and with air insufflation, then removes suspicious lesions under telescope vision. TAMIS combines TEM principles with single-incision laparoscopic surgery to reach difficult proximal rectal areas with laparoscopic instruments.\"},{\"question\":\"When can transanal surgery be used in locally advanced rectal cancer?\",\"answer\":\"Transanal surgery may be offered as part of an organ preservation strategy for locally advanced disease when combined with other modalities such as neoadjuvant chemoradiotherapy, total neoadjuvant therapy, and immunotherapy.\"}]","Current Surgical Methods in Local Rectal Excision - Review Article | PDF",1789990890,33]