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38, 1–6 [https://doi.org/10.1093/ajh/hpae099](https://doi.org/10.1093/ajh/hpae099)[ ](https://doi.org/10.1093/ajh/hpae099)Advance access publication 30 July 2024 Review  \nReview  \nCurrent Status and Future Perspective of Onco-Hypertension  \nTatsuhiko Azegami1, Hidehiro Kaneko2,3,*,, Shintaro Minegishi4, Yuta Suzuki2,5, Hiroyuki Morita2, Katsuhito Fujiu2,3, Norihiko Takeda2, Takashi Yokoo6, Yuichiro Yano7,8, Kaori Hayashi1, Akira Nishiyama9, Koichi Node10  \n1Division of Endocrinology, Metabolism and Nephrology, Department of Internal Medicine, Keio University School of Medicine, Tokyo, Japan;  \n2Department of Cardiovascular Medicine, The University of Tokyo, Tokyo, Japan;  \n3Department of Advanced Cardiology, The University of Tokyo, Tokyo, Japan;  \n4Department of Cardiology, Yokohama City University School of Medicine, Yokohama, Japan;  \n5Center for Outcomes Research and Economic Evaluation for Health, National Institute of Public Health, Saitama, Japan;  \n6Division of Nephrology and Hypertension, Department of Internal Medicine, Jikei University School of Medicine, Tokyo, Japan;  \n7Department of General Medicine, Juntendo University Faculty of Medicine, Tokyo, Japan;  \n8Noncommunicable Disease (NCD) Epidemiology Research Center, Shiga University of Medical Science, Otsu, Japan;  \n9Department of Pharmacology, Faculty of Medicine, Kagawa University, Kagawa, Japan; 10Department of Cardiovascular Medicine, Saga University, Saga, Japan  \n*Corresponding author: Hidehiro Kaneko ([kanekohidehiro@gmail.com](kanekohidehiro@gmail.com))  \nBackground Hypertension and cancer are both increasing with age. Recently, the new concept of“Onco-Hypertension”has been proposed to address the mutual risks posed by hypertension and cancer and to provide comprehensive care for patients with these two conditions in an aging society.  \nMethods In this review, we provide an overview of the current status and future perspective of the “Onco-Hypertension,” including our research findings.  \nResults Hypertension and cancer share common risk factors and may be interrelated in pathogenesis: Hypertension is involved in the development of certain cancers, and cancer survivors have a higher incidence of hypertension. With recent advances in cancer therapy, the number of cancer survivors has increased. Cancer survivors not only have a higher risk of incident hypertension but also an increased risk of future cardiovascular events, highlighting the growing importance of comprehensive care.  \nConclusions There exists a diverse array of epidemiological and pathophysiological relationships between hypertension and cancer. It is imperative to move the emerging scientific field of“Onco-Hypertension” forward through relentless research efforts.  \nKeywords: blood pressure; cancer; cardiovascular disease; hypertension; onco-hypertension; oncology.  \nGraphical Abstract  \nCancer  \nHypertension  \nReceived 15 July 2024; revised 24 July 2024; accepted 24 July 2024.  \n© The Author(s) 2024. Published by Oxford University Press on behalf of American Journal of Hypertension, Ltd.  \nThis is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License ([https://creativecommons.org/](https://creativecommons.org/)[ ](https://creativecommons.org/)[licenses/by-nc/4.0/](licenses/by-nc/4.0/)), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact [reprints@oup.com](reprints@oup.com) for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please [contact journals.permissions@oup.com](contact journals.permissions@oup.com).  \nIntroduction  \nHypertension and cancer are multifactorial and chronic diseases, with their prevalence increasing with age.1 ,2 The","cbCainNL8D8bWs4n","https://ap.wps.com/l/cbCainNL8D8bWs4n","pdf",390102,"English","# Background\n## Methods\n## Results\n## Conclusions\n# Introduction\n## Shared risk factors\n## Clinical implications for prevention and early detection","[{\"question\":\"What is the “Onco-Hypertension” concept?\",\"answer\":\"It is a new framework proposed to address the mutual risks posed by hypertension and cancer and to support comprehensive care for patients with both conditions in an aging society.\"},{\"question\":\"How are hypertension and cancer related according to the review?\",\"answer\":\"The review describes shared risk factors and interrelated pathogenesis, where hypertension can be involved in the development of certain cancers, and cancer survivors have a higher incidence of hypertension.\"},{\"question\":\"Why is comprehensive care important for cancer survivors?\",\"answer\":\"Cancer survivors not only have increased risk of incident hypertension but also an elevated risk of future cardiovascular events, making coordinated prevention and management essential.\"}]","Current Status and Future Perspective of Onco-Hypertension | PDF",1789999784,15]