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A retrospective cross-sectional study at King Hussein Medical Center (March 2014 to December 2021) evaluated all pelvic exenteration procedures. Thirty patients underwent thirty-one operations; R0 excision occurred in 21 specimens. Overall complications were 67.7% with 30-day mortality of 16.7%. 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Pan African Medical Journal (ISSN: 1937-8688) . This is an Open Access article distributed under the terms of the Creative Commons Attribution International 4.0 License ( [https://creativecommons.org/licenses/by/4.0/](https://creativecommons.org/licenses/by/4.0/)), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.  \nCite this article: Ahmad Ali Uraiqat et al. Curative pelvic exenteration: initial experience and clinical outcome. Pan African Medical Journal. 2023;44(170) . 10. 11604/pamj.2023.44.170.37182  \nAvailable online at: [https://www.panafrican-med-journal.com//content/article/44/170/full](https://www.panafrican-med-journal.com//content/article/44/170/full)  \nCurative pelvic exenteration: initial experience and clinical outcome  \nAhmad Ali Uraiqat1,&, Dania Al Nsour1, Khaled Mohammad Mestareehy1, Mohammad Saleh Allababdeh1, Mo´taz Fawzat Naffa´1, Muhanad Mohammad Alrabee1, Firas Al-Hammouri2  \n1Colorectal Unit, King Hussein Medical Center, Royal Medical Services, Amman, Jordan, 2 Prince Hussein Center for Kidney Diseases, Royal Medical Services, Amman, Jordan  \n&Corresponding author  \nAhmad Ali Uraiqat, Colorectal Unit, King Hussein Medical Center, Royal Medical Services, Amman, Jordan  \nAbstract  \nIntroduction: in patients with advanced primary or recurrent gynecologic, urologic, or rectal cancers without metastatic disease, extensive aggressive surgery such as pelvic exenteration may be necessary for curative intent treatment. This study aims to present the initial experience and clinical outcome of curative pelvic exenteration procedures for advanced or recurrent pelvic cancer in our center. Methods: a retrospective crosssectional study was conducted at the colorectal unit at King Hussein Medical Center in Amman, Jordan, between March 2014 and December 2021. All patients who underwent pelvic exenteration procedures were included in this study.  \nDemographic characteristics, type of procedure, completeness of excision, postoperative complications, morbidity, and mortality were analyzed. Results: a total of 30 patients underwent thirty-one operations. There were 22 females and eight males with a median age of 55 (range 25-86) years. Twenty-six surgeries were for advanced primary and 5 for recurrent malignancies. Twentynine operations were performed for colorectal and 2 for gynecological tumors. There were 19 posterior pelvic exenterations, 2 posterior pelvic exenterations with sacrectomy, and ten total pelvic exenterations. Completeness of tumor excision R0 was observed in 21 specimens, incomplete (R1/R2) in 6 specimens. The overall complication rate was 67.7% and 30-day mortality was 16.7%. Ten (33.3%) patients are disease free at a median follow-up of 22 months. Conclusion: in our study, pelvic exenteration provides above 40% overall survival at a median follow-up of two years. Gaining experience in this type of procedure, a multidisciplinary approach, careful patients'selection, and preoperative counseling will reduce postoperative morbidity and mortality.  \nIntroduction  \nColorectal cancer is the third commonest malignancy and second in terms of mortality worldwide [1] . In Jordan, it is the second most common cancer among women and the third among men according to the latest Global Cancer Observatory (GLOBOCAN) estimation in 2018 [2] . In","cbCaihp8mX9r9TcZ","https://ap.wps.com/l/cbCaihp8mX9r9TcZ","pdf",915286,13,"English","# Abstract\n## Introduction\n## Methods\n## Results\n## Conclusion\n# Introduction\n## Colorectal cancer background and surgical rationale\n## Role of pelvic exenteration (PE) and margin status","[{\"question\":\"What was the goal of the study on curative pelvic exenteration?\",\"answer\":\"To present the initial experience and clinical outcome of curative pelvic exenteration procedures for advanced or recurrent pelvic cancer in the center.\"},{\"question\":\"How was the study conducted and what time period was analyzed?\",\"answer\":\"A retrospective cross-sectional study was conducted in the colorectal unit at King Hussein Medical Center in Amman, Jordan, between March 2014 and December 2021.\"},{\"question\":\"What were the key clinical outcomes reported?\",\"answer\":\"Thirty patients underwent thirty-one operations; R0 excision was observed in 21 specimens. The overall complication rate was 67.7% and 30-day mortality was 16.7%, with 10 patients disease-free at a median follow-up of 22 months.\"}]","Curative pelvic exenteration: initial experience and clinical outcome - Research | PDF",1790562324,33]