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Among 121 participants, 18.2% had any EHD, including 9.1% with supraventricular tachyarrhythmias (5% atrial fibrillation) and 7.4% with atrioventricular block. Clinically relevant EHD were found in 9.9%. Adjusted analyses linked SVT to older age and higher BMI, and linked conduction delays and clinically relevant EHD to age, hypertension, and longer disease-modifying antirheumatic-drug treatment duration. 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Vicente-Rabaneda 4,  \nMiguel A. González-Gay 5,6, Fernando Alfonso 3,† and Santos Castañeda 4, *,†  \nAcademic Editor: Anna Kabłak-Ziembicka  \nReceived: 9 December 2025  \nRevised: 24 December 2025  \nAccepted: 31 December 2025  \nPublished: 3 January 2026  \nCopyright: © 2026 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.  \n1 Cardiology Division, Hospital Universitario Príncipe de Asturias, 28805 Madrid, Spain  \n2 Internal Medicine Division, Hospital Universitario Infanta Leonor, 28031 Madrid, Spain  \n3 Cardiology Division, Hospital Universitario de La Princesa, IIS-Princesa, 28006 Madrid, Spain  \n4 Rheumatology Division, Hospital Universitario de La Princesa, IIS-Princesa, 28006 Madrid, Spain  \n5 Rheumatology Division, Hospital Universitario Fundación Jiménez Díaz, 28040 Madrid, Spain  \n6 Department of Medicine, Universidad de Cantabria, 39011 Santander, Spain  \n* Correspondence: [crodriguez@salud.madrid.org](crodriguez@salud.madrid.org) (C.R.-L.); [scastas@gmail.com](scastas@gmail.com) (S.C.)† These authors contributed equally to this work.  \nAbstract  \nBackground/Objectives: Ankylosing spondylitis (AS) has been associated with various comorbidities, including cardiovascular morbidity. Recent studies suggest that certain arrhythmias may be more frequent in AS patients than in the general population. The aim of this study was to analyze the prevalence of electric heart disorders (EHD) in patients with AS in real-world conditions and compare them with those reported in the general population. Methods: Descriptive cross-sectional study aiming to determine the prevalence of EHD in AS in pre-COVID-19 period. EHD were analyzed in a resting ECG and 24 h Holter monitoring. Additionally, the association between clinical and demographic variables was analyzed. Results: Among 121 patients with AS (62% men; mean ± SD age 54.6 ± 15.6 years; median [IQR] disease duration 14 (8–20) years), 18.2% presented any EHD, including 9.1% with supraventricular tachyarrhythmias (SVT) (5% atrial fibrillation [AF]) and 7.4% with atrioventricular block (AVB) . Clinically relevant disorders (≥2nd-degree AVB or SVT) were observed in 9.9% of patients. In adjusted analyses, SVTwas independently associated with older age and higher BMI, while any conduction delay and clinically relevant EHD were associated with age, hypertension, and disease-modifying antirheumatic-drug treatment duration. Comparisons with previous population-based studies showed similar data, with a non-significant trend toward higher AF prevalence in AS patients. Conclusions: There appears to be a trend toward a higher prevalence of arrhythmias in patients with AS in real-world conditions, which could have clinical and therapeutic implications. An association between EHD and pro-inflammatory conditions such as age and BMI was observed, supporting the hypothesis that underlying inflammation might contribute to increased arrhythmogenicity.  \nKeywords: ankylosing spondylitis; arrhythmias; electric heart disorders; atrial fibrillation; atrioventricular block; inflammation  \n1. Introduction  \nAnkylosing spondylitis (AS) is a chronic inflammatory rheumatic disease that primarily affects the axial skeleton and frequently involves the peripheral joints, being the  \nmost common condition within the group of spondyloarthritides (SpA) . The main musculoskeletal symptoms include spondylitis, oligoarthritis, and enthesitis, but extra-articular manifestations are also common [1], including uveitis (23%), inflammatory bowel disease (6.4%) [2], and cardiovascular (CV) involvemen","cbCaivdVRNLXsxJs","https://ap.wps.com/l/cbCaivdVRNLXsxJs","pdf",366414,13,"English","# Abstract\n## Background/Objectives\n## Methods\n## Results\n## Conclusions\n# Introduction","[{\"question\":\"What was the aim of the study on AS patients and electric heart disorders?\",\"answer\":\"To analyze the prevalence of electric heart disorders in patients with ankylosing spondylitis under real-world conditions and compare it with data reported in the general population.\"},{\"question\":\"How were electric heart disorders assessed in the participants?\",\"answer\":\"EHD were evaluated using a resting ECG and 24 h Holter monitoring, and associations with clinical and demographic variables were analyzed.\"},{\"question\":\"What proportion of AS patients showed electric heart disorders, and which types were most common?\",\"answer\":\"Among 121 AS patients, 18.2% presented any EHD. Supraventricular tachyarrhythmias occurred in 9.1% (including atrial fibrillation at 5%), and atrioventricular block occurred in 7.4%.\"}]","Cross-Sectional Study on Electrocardiographic Disorders in Patients with Ankylosing Spondylitis in Real-World Conditions | PDF",1790761884,33]