[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-detail-446197-en":59,"doc-seo-446197-105":81},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":5,"data":60},{"doc_id":61,"user_id":62,"nickname":63,"user_avatar":64,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":66,"doc_content":67,"file_id":68,"file_url":69,"file_type":70,"file_size":71,"view_count":72,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":52,"language":73,"language_code":74,"site_id":75,"html_lang":74,"table_of_contents":76,"faqs":77,"seo_title":78,"seo_description":66,"update_tm":79,"read_time":80},446197,549768702563,"Fahsai","https://ap-avatar.wpscdn.com/avatar/8000c4aa63b76e948b?x-image-process=image/resize,m_fixed,w_180,h_180&k=1786536092046926083","Cost-effectiveness of atrial fibrillation screening programmes across European nations","Population ageing in Europe is expected to increase atrial fibrillation (AF) incidence, raising public health costs, particularly in older adults, largely through more stroke cases. Early AF detection enables timely oral anticoagulant (OAC) treatment to lower stroke risk. This study evaluates the cost-effectiveness of implementing AF screening programmes in Denmark, Germany, Ireland, Italy, the Netherlands, Serbia, Spain, and Sweden using a Markov cohort framework and probabilistic sensitivity analysis.","European Heart Journal ‐ Quality of Care and Clinical Outcomes (2026) 12, 83–92 [https://doi.org/10.1093/ehjqcco/qcaf099](https://doi.org/10.1093/ehjqcco/qcaf099)  \nORIGINAL ARTICLE  \nCost-effectiveness of atrial fibrillation screening programmes across European nations  \nLars Bernfort  1,*, Johan Lyth  1, Kajsa Appelberg  1, Giuseppe Boriani  2, Claire M. Buckley  3, Søren Zöga Diederichsen  4, Michaela Eklund  1,  \nDaniel Engler  5, Ben Freedman  6, Tatjana S. Potpara  7,8, Renate B. Schnabel  5, Jesper Hastrup Svendsen  4,9, and Lars-Åke Levin  1  \n1Department of Health, Medicine and Caring Sciences, Linköping University, Campus US, Linköping 581 83, Sweden; 2Cardiology Division, Department of Biomedical, Metabolic and Neural Sciences, University of Modena and Reggio Emilia, Policlinico di Modena, 411 24 Modena, Italy; 3School of Public Health, University College Cork, T12K8AF Cork, Ireland; 4Department of Cardiology, The Heart Centre, Copenhagen University Hospital—Rigshospitalet, 2200 Copenhagen, Denmark; 5Department of General and Interventional Cardiology, The University Medical Center Hamburg-Eppendorf, 202 51 Hamburg, Germany; 6Heart Research Institute, Charles Perkins Centre and Faculty of Medicine and Health, The University of Sydney, NSW 2042 Sydney, Australia; 7School of Medicine, University of Belgrade, 11000 Belgrade, Serbia; 8Department for Intensive Arrhythmia Care, Cardiology Clinic, Clinical Center of Serbia, 11000 Belgrade, Serbia; and 9Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, DK-1165 Copenhagen, Denmark  \nReceived 16 June 2025; revised 25 July 2025; accepted 11 August 2025; online publish-ahead-of-print 25 August 2025  \nAims Due to the ageing population in Europe, a significant increase in the incidence of atrial fibrillation (AF) is anticipated. This is  \npredicted to have a detrimental impact on public health costs, particularly among the elderly, because of an increased number of stroke cases. Early detection of AF is crucial for initiating treatment with oral anticoagulants (OACs) to reduce the risk of stroke. This study aims to assess the cost-effectiveness of implementing AF screening programmes in eight European countries: Denmark, Germany, Ireland, Italy, the Netherlands, Serbia, Spain, and Sweden.  \nMethods and results  \nThe analysis concerned invitation to AF population screening for 75-year-olds. A Markov cohort model was used, considering the prevalence of AF, screening yield, the use of different OACs, estimated clinical events, mortality, quality of life and costs. The model used country-specific parameters to produce specific cost-effectiveness estimates. Probabilistic sensitivity analyses were conducted to assess the impact of parametric uncertainties on the results. Inviting 75-year-olds to AF screening proved to be cost-effective across all eight countries analysed. In all countries, the strategy was dominant, meaning that quality-adjusted life-years were gained at lower costs. The time to financial break-even ranged from 6 to 14 years.  \nConclusion This study indicates that population-based AF screening of 75-year-olds is a cost-effective strategy across eight European countries, meaning that adoption of such a strategy has the potential to make healthcare systems in these countries more efficient. The heterogeneity among European countries suggests that AF screening programmes may need to be tailored to the specific healthcare systems and conditions of each nation.  \n*Corresponding author. Tel: +46 700 85 05 30, Email: [lars.bernfort@liu.se](lars.bernfort@liu.se)  \nThe work was performed at the Department of Health, Medicine and Caring Sciences, Linköping University, Sweden.  \n© The Author(s) 2025. Published by Oxford University Press on behalf of the European Society of Cardiology.  \nThis is an Open Access article distributed under the terms of the Creative Commons Attribution License ([https://creativecommons.org/licenses/by/4.","cbCaiotOEnhOC3K9","https://ap.wps.com/l/cbCaiotOEnhOC3K9","pdf",869807,3,"English","en",105,"# Aims\n# Methods and results\n# Conclusion\n# Key learning points\n## What is already known\n## What this study adds\n# Introduction","[{\"question\":\"What problem does the study address?\",\"answer\":\"It addresses the expected rise in atrial fibrillation in Europe due to ageing, which could increase healthcare costs—especially from stroke in older people—by improving early detection and treatment.\"},{\"question\":\"How did the authors assess cost-effectiveness?\",\"answer\":\"They used a Markov cohort model for inviting 75-year-olds to AF population screening, incorporating country-specific parameters, clinical events, mortality, quality of life, and costs, with probabilistic sensitivity analyses.\"},{\"question\":\"What were the main findings across countries?\",\"answer\":\"Inviting 75-year-olds to AF screening was cost-effective in all eight countries. The strategy was dominant, yielding quality-adjusted life-years at lower costs, with a financial break-even time ranging from 6 to 14 years.\"}]","Cost-effectiveness of atrial fibrillation screening programmes across European nations | PDF",1790714428,25,{"code":4,"msg":82,"data":83},"ok",{"site_id":75,"language":74,"slug":84,"title":65,"keywords":85,"description":66,"schema_data":86,"social_meta":139,"head_meta":141,"extra_data":143,"updated_unix":144},"cost-effectiveness-of-atrial-fibrillation-screening-programmes-across-european-nations","",{"@graph":87,"@context":138},[88,101,121],{"@type":89,"itemListElement":90},"BreadcrumbList",[91,95,97,99],{"item":92,"name":93,"@type":94,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":96,"name":9,"@type":94,"position":14},"https://docshare.wps.com/document/",{"item":98,"name":40,"@type":94,"position":72},"https://docshare.wps.com/document/research-report/",{"item":100,"name":65,"@type":94,"position":19},"https://docshare.wps.com/document/cost-effectiveness-of-atrial-fibrillation-screening-programmes-across-european-nations/446197/",{"url":100,"name":65,"@type":102,"image":103,"author":108,"headline":65,"publisher":110,"fileFormat":113,"inLanguage":74,"description":66,"dateModified":114,"datePublished":115,"encodingFormat":113,"isAccessibleForFree":116,"interactionStatistic":117},"DigitalDocument",{"url":104,"@type":105,"width":106,"height":107},"https://docshare.wps.com/thumbnails/cost-effectiveness-of-atrial-fibrillation-screening-programmes-across-european-nations/446197.png","ImageObject",300,407,{"name":63,"@type":109},"Person",{"url":92,"name":111,"@type":112},"DocShare","Organization","application/pdf","2026-10-05","2026-09-29",true,{"@type":118,"interactionType":119,"userInteractionCount":72},"InteractionCounter",{"@type":120},"ViewAction",{"@type":122,"mainEntity":123},"FAQPage",[124,130,134],{"name":125,"@type":126,"acceptedAnswer":127},"What problem does the study address?","Question",{"text":128,"@type":129},"It addresses the expected rise in atrial fibrillation in Europe due to ageing, which could increase healthcare costs—especially from stroke in older people—by improving early detection and treatment.","Answer",{"name":131,"@type":126,"acceptedAnswer":132},"How did the authors assess cost-effectiveness?",{"text":133,"@type":129},"They used a Markov cohort model for inviting 75-year-olds to AF population screening, incorporating country-specific parameters, clinical events, mortality, quality of life, and costs, with probabilistic sensitivity analyses.",{"name":135,"@type":126,"acceptedAnswer":136},"What were the main findings across countries?",{"text":137,"@type":129},"Inviting 75-year-olds to AF screening was cost-effective in all eight countries. The strategy was dominant, yielding quality-adjusted life-years at lower costs, with a financial break-even time ranging from 6 to 14 years.","https://schema.org",{"og:url":100,"og:type":140,"og:title":65,"og:site_name":111,"og:description":66},"article",{"robots":142,"canonical":100},"index,follow",{"doc_id":61,"site_id":75},1791164755]