[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-326747-105":59,"doc-detail-326747-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","correlation-between-sarcopenia-and-esophageal-cancer-a-narrative-review","Correlation between sarcopenia and esophageal cancer - a narrative review","","Rapid growth in studies has examined how sarcopenia before and after esophageal cancer treatment relates to patient prognosis, attracting clinical attention to esophageal cancer complicated with sarcopenia. This narrative review assesses sarcopenia prevalence in esophageal cancer and the association between sarcopenia (pre-treatment and after surgery or chemotherapy) and outcomes. It also summarizes potential mechanisms and available pharmacologic and non-pharmacologic therapies.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/correlation-between-sarcopenia-and-esophageal-cancer-a-narrative-review/326747/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/correlation-between-sarcopenia-and-esophageal-cancer-a-narrative-review/326747.png","ImageObject",300,407,{"name":92,"@type":93},"Logic","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-01","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What does the review focus on regarding sarcopenia and esophageal cancer?","Question",{"text":112,"@type":113},"It reviews sarcopenia prevalence in patients with esophageal cancer and evaluates the relationship between sarcopenia (before treatment and after surgery or chemotherapy) and prognosis.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How common is sarcopenia among patients with esophageal cancer, according to the review?",{"text":117,"@type":113},"The review reports an average sarcopenia prevalence of 46.3% ± 19.6%, with a range from 14.4% to 81%.",{"name":119,"@type":110,"acceptedAnswer":120},"Why can esophageal cancer patients develop sarcopenia?",{"text":121,"@type":113},"The review attributes sarcopenia to nutritional deficiencies, reduced physical activity, chemotherapy, and the effects of certain inflammatory factors and pathways.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},326747,1790183302,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":36,"preview_page_count":4},1099513958762,"https://ap-avatar.wpscdn.com/avatar/1000023916a998db790?x-image-process=image/resize,m_fixed,w_180,h_180&k=1784791008015729253","Li etal. World Journal of Surgical Oncology (2024) 22:27  \n[https://doi.org/10.1186/s12957-024-03304-w](https://doi.org/10.1186/s12957-024-03304-w)  \nWorld Journal of Surgical Oncology  \n REVIEW Open Access  \nCorrelation between sarcopenia  \nand esophageal cancer: a narrative review  \nShenglan Li1,2,3,4, Kaiqiang Xie1,2,3,4, Xiaoxiong Xiao2,5,6, Pingsheng Xu7, Mimi Tang1,2,3,4* and Dai Li2,7*  \nAbstract  \nBackground In recent years, the research on the relationship between sarcopenia before and after the treatment of esophageal cancer, as well as its impact on prognosis of esophageal cancer, has increased rapidly, which has aroused people’s attention to the disease of patients with esophageal cancer complicated with sarcopenia.  \nThis review examines the prevalence of sarcopenia in patients with esophageal cancer, as well as the relationship between sarcopenia (before and after surgery or chemotherapy) and prognosis in patients with esophageal cancer. Moreover, we summarized the potential pathogenesis of sarcopenia and pharmacologic and non-pharmacologic therapies.  \nMethods A narrative review was performed in PubMed and Web of Science using the keywords (“esophageal cancer” or “esophageal neoplasm” or “neoplasm, esophageal” or “esophagus neoplasm” or “esophagus neoplasms”or “neoplasm, esophagus” or “neoplasms, esophagus” or “neoplasms, esophageal” or “cancer of esophagus” or“cancer of the esophagus” or“esophagus cancer” or “cancer, esophagus” or “cancers, esophagus” or “esophagus cancers”or “esophageal cancer” or “cancer, esophageal” or “cancers, esophageal” or “esophageal cancers”) and (“sarcopenia”or “muscular atrophy” or “aging” or “senescence” or “biological aging” or “aging, biological” or “atrophies, muscular”or “atrophy, muscular” or “muscular atrophies” or “atrophy, muscle” or “atrophies, muscle” or “muscle atrophies”) . Studies reporting relationship between sarcopenia and esophageal cancer were analyzed.  \nResults The results of the review suggest that the average prevalence of sarcopenia in esophageal cancer was 46. 3% ± 19. 6% ranging from 14.4 to 81% and sarcopenia can be an important predictor of poor prognosis in patients with esophageal cancer. Patients with esophageal cancer can suffer from sarcopenia due to their nutritional deficiencies, reduced physical activity, chemotherapy, and the effects of certain inflammatory factors and pathways. When classic diagnostic values for sarcopenia such as skeletal muscle index (SMI) are not available clinically, it is also feasible to predict esophageal cancer prognosis using simpler metrics, such as calf circumference (CC), fivecount sit-up test (5-CST), and six-minute walk distance (6MWD) .  \nConclusions Identifying the potential mechanism of sarcopenia in patients with esophageal cancer and implementing appropriate interventions may hold the key to improving the prognosis of these patients.  \nKeywords Esophageal cancer, Sarcopenia, Treatment, Prognosis  \n*Correspondence:  \nMimi Tang [tangmimi1989@csu.edu.cn](tangmimi1989@csu.edu.cn)[ ](tangmimi1989@csu.edu.cn)Dai Li  \n[lidai01@csu.edu.cn](lidai01@csu.edu.cn)  \nFull list of author information is available at the end of the article  \n© The Author(s) 2024. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a c","cbCaiqslwdYRhmNE","https://ap.wps.com/l/cbCaiqslwdYRhmNE","pdf",964113,16,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusions\n# Introduction","[{\"question\":\"What does the review focus on regarding sarcopenia and esophageal cancer?\",\"answer\":\"It reviews sarcopenia prevalence in patients with esophageal cancer and evaluates the relationship between sarcopenia (before treatment and after surgery or chemotherapy) and prognosis.\"},{\"question\":\"How common is sarcopenia among patients with esophageal cancer, according to the review?\",\"answer\":\"The review reports an average sarcopenia prevalence of 46.3% ± 19.6%, with a range from 14.4% to 81%.\"},{\"question\":\"Why can esophageal cancer patients develop sarcopenia?\",\"answer\":\"The review attributes sarcopenia to nutritional deficiencies, reduced physical activity, chemotherapy, and the effects of certain inflammatory factors and pathways.\"}]","Correlation between sarcopenia and esophageal cancer - a narrative review | PDF",1789975243]