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The article is presented as an open-access original research work in oncology and includes extensive institutional affiliations and corresponding authors. 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R. China  \n2The First Clinical Medicine College, Nanjing Medical University, Nanjing, Jiangsu, P. R. China  \n3 Departments of Gynecology, Wuxi Maternal and Child Health Care Hospital, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, P. R. China  \n4 Departments of Oncology, Xuzhou Central Hospital, The Xuzhou School of Clinical Medicine of Nanjing Medical University, Xuzhou, Jiangsu, P. R. China  \n5 Department of Sports Medicine, Huashan Hospital Affiliated to Fudan University, Shanghai, P. R. China  \n6 Department of Sports Medicine, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, P. R. China  \n7 Departments of Oncology, The Affiliated Wuxi People’s Hospital of Nanjing Medical University, Wuxi Medical Center, Nanjing Medical University, Wuxi, Jiangsu, P. R. China  \n8 Shanghai Outdo Biotech Co., Ltd., National Engineering Center for Biochip, Shanghai, P. R. China  \n9 Departments of Gynecology, Wuxi Maternity and Child Health Care Hospital, Affiliated Women’s Hospital of Jiangnan University, Wuxi, Jiangsu, P. R. China  \n10 Department of Physiology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, Jiangsu, P. R. China  \nList of abbreviations: ICB, immune checkpoint blockade; PD-1, programmed cell death 1; PD-L1, programmed cell death 1 ligand 1; CTLA4, cytotoxic T-lymphocyte associated antigen 4; TME, tumor microenvironment; TMB, tumor mutational burden; ECM, extracellular matrix; CAF, cancer-associated fibroblast; TIME, tumor immune microenvironment; TCGA, the Cancer Genome Atlas; OS, overall survival; GSEA, gene sets enrichment analysis; GSVA, Gene Set Variation Analysis; NSCLC, non-small cell lung cancer; TMA, tissue microarray; TNBC, triple negative breast cancer; FPKM, Fragments Per Kilobase of exon model per Million mapped reads; HE, hematoxylin and eosin; TIIC, tumor-infiltrating immune cell; CPS, Combined Positive Score; V, volume; PBS, phosphate belanced solution; GR1, lymphocyte antigen 6 complex, locus G/C; scRNA-seq, single-cell RNA-sequencing; 4NQO, 4-Nitroquinoline N-oxide; PCA, principal component analysis; PC, principal component; DCN, decorin; ANOVA, one-way analysis of variance; ROC, receiver-operating characteristic; AUC, area under the ROC curve; TGF-β, transforming growth factor-β; DDR1, discoidindomain receptor tyrosine kinase 1; MHC, major histocompatibility complex; NTNBC, non-TNBC; PD-L1 IC score, PD-L1 expression score in immune cell; PD-L1 TC score, PD-L1 expression score in tumor cell; FAP, fibroblast activation protein; MDSC, myeloid-derived suppressor cell; MSI-H, microsatellite instability-high; dMMR, mismatch repair deficient; EBV, Epstein-Barr virus; FGFR, fibroblast growth factor receptor; PDGFR, platelet-derived growth factor receptor; B7-H3, B7 homolog 3; KDR, kinase insert domain receptor; ERBB, erb-b2 receptor tyrosine kinase; PVRL4, poliovirus receptor-related 4; FOLR, folate receptor; ACC, adrenocortical carcinoma; BLCA, bladder urothelial carcinoma; BRCA, breast invasive carcinoma; CESC, cervical & endocervical cancer; CHOL, cholangiocarcinoma; COAD, colon adenocarcinoma; ESCA, esophageal carcinoma; GBM, glioblastoma multiforme; HNSC, head and neck squamous cell carcinoma; KICH, kidney chromophobe; KIRC, kidney renal clear cell carcinoma; KIRP, kidney renal papillary cell carcinoma; LGG, brain lower grade glioma; LIHC, liver hepatocellular carcinoma; LUAD, lung adenocarcinoma; LUSC, lung squamous cell carcinoma; ME","cbCaiaOL51MJMLDT","https://ap.wps.com/l/cbCaiaOL51MJMLDT","pdf",18773017,22,"English","# Original Article\n## Background and study focus\n## Authors and affiliations\n## List of abbreviations\n## Open access and licensing info\n## Correspondence contacts","[{\"question\":\"What therapy response does the study focus on predicting?\",\"answer\":\"The study focuses on predicting response to immune checkpoint blockade (ICB).\"},{\"question\":\"What are immuno-collagenic subtypes in the context of this article?\",\"answer\":\"The study focuses on predicting response to immune checkpoint blockade (ICB).\"},{\"question\":\"Who is responsible for correspondence in the article?\",\"answer\":\"Correspondence is provided by listed authors including Yongmei Yin, Yan Zhang, and Yichao Zhu (and additional corresponding contacts shown in the text).\"},{\"question\":\"What licensing terms apply to the article?\",\"answer\":\"The article is open access under the Creative Commons Attribution-NonCommercial-NoDerivs License, allowing use and distribution with proper citation and non-commercial, no-modification conditions.\"}]","Conserved immuno-collagenic subtypes predict response to immune checkpoint blockade | PDF",1789996719,55]