[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-32601":3,"doc-seo-32601":26},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"file_id":15,"file_url":16,"file_type":17,"file_size":18,"view_count":4,"is_deleted":4,"is_public":19,"is_downloadable":19,"audit_status":19,"page_count":11,"language":20,"language_code":21,"table_of_contents":22,"faqs":23,"seo_title":13,"seo_description":14,"update_tm":24,"read_time":25},32601,16904993612988,"Olivia Brown","https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd",8,"Research & Report","Comparison of Porcine Versus Bovine Surfactant in Preterm Respiratory Distress Syndrome","This retrospective, multicenter real-world study evaluated clinical effects of porcine surfactant (200 mg/kg) versus bovine surfactant (100 mg/kg) in preterm neonates with respiratory distress syndrome (RDS). Data from August 2019 to December 2022 across 6 tertiary centers analyzed combined death or chronic lung disease (CLD), redosing, and other morbidities, including subgroup outcomes for gestational age over 28 weeks. Porcine surfactant showed higher death/CLD (30% vs 13%; OR 2.7; p=0.001) with similar redosing and other morbidities. Results support further efficacy assessment in randomized trials.","cbCaiuv5B1VA3daY","https://ap.wps.com/l/cbCaiuv5B1VA3daY","pdf",196582,1,"English","en","# Abstract\n## Background & Objectives\n## Methods\n## Results\n## Conclusion\n# Study Details","[{\"question\":\"What was the study aim regarding surfactant choice in preterm RDS?\",\"answer\":\"The study aimed to evaluate the clinical effect of different surfactant types by comparing porcine versus bovine surfactant doses used in preterm respiratory distress syndrome.\"},{\"question\":\"How was the study conducted and what time period did it cover?\",\"answer\":\"A retrospective analysis was conducted from August 2019 to December 2022 across six tertiary centers, enrolling preterm neonates (24–34 weeks) with RDS requiring either porcine or bovine surfactant.\"},{\"question\":\"What did the results show about death or chronic lung disease between groups?\",\"answer\":\"The combined outcome of death or CLD was higher with porcine surfactant than bovine surfactant (30% vs 13%; OR 2.7; p=0.001), with similar results in the subgroup over 28 weeks.\"},{\"question\":\"Did other outcomes like redosing and morbidities differ between surfactant types?\",\"answer\":\"Redosing rates were similar between groups, and other morbidities such as air leak, invasive ventilation, and CPAP duration did not show significant differences.\"}]",1781738694,20,{"code":4,"msg":27,"data":28},"ok",{"site_id":29,"language":21,"slug":30,"title":13,"keywords":31,"description":14,"schema_data":32,"social_meta":87,"head_meta":89,"extra_data":91,"updated_unix":24},105,"comparison-of-porcine-versus-bovine-surfactant-in-preterm-respiratory-distress-syndrome","",{"@graph":33,"@context":86},[34,51,65],{"@type":35,"itemListElement":36},"BreadcrumbList",[37,41,45,48],{"item":38,"name":39,"@type":40,"position":19},"https://docshare.wps.com","Home","ListItem",{"item":42,"name":43,"@type":40,"position":44},"https://docshare.wps.com/document/","Document",2,{"item":46,"name":12,"@type":40,"position":47},"https://docshare.wps.com/document/research-report/",3,{"item":49,"name":13,"@type":40,"position":50},"https://docshare.wps.com/document/comparison-of-porcine-versus-bovine-surfactant-in-preterm-respiratory-distress-syndrome/32601/",4,{"url":49,"name":13,"@type":52,"author":53,"headline":13,"publisher":55,"fileFormat":58,"description":14,"dateModified":59,"datePublished":59,"encodingFormat":58,"isAccessibleForFree":60,"interactionStatistic":61},"DigitalDocument",{"name":9,"@type":54},"Person",{"url":38,"name":56,"@type":57},"DocShare","Organization","application/pdf","2026-06-17",true,{"@type":62,"interactionType":63,"userInteractionCount":4},"InteractionCounter",{"@type":64},"ViewAction",{"@type":66,"mainEntity":67},"FAQPage",[68,74,78,82],{"name":69,"@type":70,"acceptedAnswer":71},"What was the study aim regarding surfactant choice in preterm RDS?","Question",{"text":72,"@type":73},"The study aimed to evaluate the clinical effect of different surfactant types by comparing porcine versus bovine surfactant doses used in preterm respiratory distress syndrome.","Answer",{"name":75,"@type":70,"acceptedAnswer":76},"How was the study conducted and what time period did it cover?",{"text":77,"@type":73},"A retrospective analysis was conducted from August 2019 to December 2022 across six tertiary centers, enrolling preterm neonates (24–34 weeks) with RDS requiring either porcine or bovine surfactant.",{"name":79,"@type":70,"acceptedAnswer":80},"What did the results show about death or chronic lung disease between groups?",{"text":81,"@type":73},"The combined outcome of death or CLD was higher with porcine surfactant than bovine surfactant (30% vs 13%; OR 2.7; p=0.001), with similar results in the subgroup over 28 weeks.",{"name":83,"@type":70,"acceptedAnswer":84},"Did other outcomes like redosing and morbidities differ between surfactant types?",{"text":85,"@type":73},"Redosing rates were similar between groups, and other morbidities such as air leak, invasive ventilation, and CPAP duration did not show significant differences.","https://schema.org",{"og:url":49,"og:type":88,"og:title":13,"og:site_name":56,"og:description":14},"article",{"robots":90,"canonical":49},"index,follow",{"doc_id":7,"site_id":29}]