[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-332866-105":59,"doc-detail-332866-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","colorectal-cancer-complicated-with-chronic-schistosoma-japonicum-infected-a-case-report","Colorectal Cancer Complicated with Chronic Schistosoma Japonicum Infected - A Case Report","","Colonic schistosomiasis poses major diagnostic challenges in endemic regions due to nonspecific symptoms and overlapping radiographic findings. A case report describes a 67-year-old male with intermittent hematochezia and coexisting colorectal cancer and chronic Schistosoma japonicum infection. Initial colonoscopy showed multiple sigmoid and rectal mucosal elevations; CT and endoscopic ultrasonography suggested multiple lesions and high echogenic changes. Endoscopic submucosal dissection identified rectal adenocarcinoma and sigmoid tubular adenoma with extensive egg deposition, and postoperative pathology confirmed moderately differentiated adenocarcinoma with chronic schistosomiasis. The report emphasizes integrating colonoscopy, histopathology, and adjunct tests and maintaining suspicion in endemic patients.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/colorectal-cancer-complicated-with-chronic-schistosoma-japonicum-infected-a-case-report/332866/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/colorectal-cancer-complicated-with-chronic-schistosoma-japonicum-infected-a-case-report/332866.png","ImageObject",300,407,{"name":92,"@type":93},"Clementine","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-06","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why is colonic schistosomiasis difficult to diagnose in endemic areas?","Question",{"text":112,"@type":113},"It often presents with nonspecific clinical symptoms and radiographic features that can resemble other gastrointestinal conditions, creating diagnostic uncertainty.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What diagnostic steps confirmed the coexistence of colorectal cancer and chronic Schistosoma japonicum infection?",{"text":117,"@type":113},"Colonoscopy findings were followed by CT and endoscopic ultrasonography, and endoscopic submucosal dissection provided tissue for histopathology, which showed both adenocarcinoma and extensive egg deposition.",{"name":119,"@type":110,"acceptedAnswer":120},"What clinical message does the case report emphasize for patients from endemic regions?",{"text":121,"@type":113},"Clinicians should maintain a high index of suspicion for schistosomiasis when gastrointestinal symptoms occur, using detailed medical histories and appropriate screening to reduce misdiagnosis risk.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},332866,1790697813,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},1374391974564,"https://ap-avatar.wpscdn.com/avatar/14000253aa45c000a9e?x-image-process=image/resize,m_fixed,w_180,h_180&k=1779874745381141002","Acta Parasitologica (2024) 69:2064–2068  \n[https://doi.org/10.1007/s1](https://doi.org/10.1007/s1) 1686-024-00919-7  \nCASE REPORT  \nColorectal Cancer Complicated with Chronic SchistosomaJaponicum Infected: A Case Report  \nShan Li1 · Yuling Shen1 · Ting Li2 · Yanqing Shi2  \nReceived: 19 June 2024 / Accepted: 27 August 2024 / Published online: 3 September 2024 © The Author(s) 2024  \nAbstract  \nBackground Colonic schistosomiasis is a significant health issue in endemic areas, presenting diagnostic challenges due to its nonspecific clinical symptoms and radiographic features. This case report highlights a patient with concomitant colorectal cancer and chronic Schistosomajaponicum infection, emphasizing the need for a comprehensive diagnostic approach.  \nCase Presentation A 67-year-old male from an endemic region presented with a six-month history of intermittent hematochezia. Initial colonoscopy revealed multiple mucosal elevations in the sigmoid colon and rectum. Subsequent investigations, including CT scans and endoscopic ultrasonography, indicated high echogenic changes and multiple lesions. The patient underwent endoscopic submucosal dissection (ESD), revealing adenocarcinoma of the rectal mucosa and tubular adenoma in the sigmoid colon, both with extensive deposition of Schistosoma japonicum eggs. Postoperative pathology confirmed the diagnosis of moderately differentiated adenocarcinoma with chronic schistosomiasis.  \nConclusion This case underscores the diagnostic complexity of colonic schistosomiasis, particularly when coexisting with malignancy. The integration of colonoscopy, histopathology, and auxiliary tests is crucial for accurate diagnosis. Clinicians should maintain a high index of suspicion for schistosomiasis in patients from endemic areas presenting with gastrointestinal symptoms. Regular screening and detailed medical histories are essential for early detection and treatment, improving patient outcomes and reducing the risk of misdiagnosis.  \nKeywords Colorectal cancer · Schistosoma Japonicum · Case Report  \nBackground  \nColorectal cancer (CRC) is a malignant lesion of the intestinal mucosal epithelium that occurs under the action of various carcinogenic factors such as environment or genetics [1], and it was the third most common malignancy and the second leading cause of cancer-related mortality in the world [2, 3] . Investigations have shown that about 17% of tumor patients can be attributed to chronic infections, and  \nShan Li and Yuling Shen contributed equally to this work.  \n􀀍 Yanqing Shi [710327101@qq.com](710327101@qq.com)  \n1 Jiangxi Provincial Key Laboratory of Cell Precision Therapy, School of Basic Medical Sciences, Jiujiang University, Jiujiang 332005, The People’s Republic of China  \n2 Department of Gastroenterology, Affiliated Hospital of Jiujiang University, Jiujiang  \n332005, The People’s Republic of China  \ninfection is considered one of the main factors in tumor development [4, 5] . Previous studies have indicated that the incidence of colorectal cancer in patients infected with Schistosomajaponicum is significantly higher than that of the normal population, with a three fold higher risk of developing the disease than non-infected individuals. The portal vein and mesenteric venous systems of the human body are the optimal environment for the survival of schistosomes. During long-term parasitism, a large number of eggs produced by schistosomes can alter the intestinal environment, providing conditions for tumor occurrence and exacerbating the occurrence of cancer CRC [6] . A possible mechanism for the induction of cancer by intestinal schistosomiasis may be the deposition of schistosome eggs in the digestive tract and the accumulation of a large number of eggs under the intestinal mucosa, which may lead to chronic mucosal inflammation, thus resulting in polypoid hyperplasia and canceration [7] . However, the exact mechanism of their interaction is not yet entirely clear. Here, we present a ca","cbCaieUBwVzmEAzn","https://ap.wps.com/l/cbCaieUBwVzmEAzn","pdf",2147779,"English","# Background\n## Colorectal cancer and chronic infection risk\n# Case Presentation\n## General information and initial findings\n## Diagnostic workup and pathology\n# Conclusion\n## Diagnostic complexity and clinical recommendations","[{\"question\":\"Why is colonic schistosomiasis difficult to diagnose in endemic areas?\",\"answer\":\"It often presents with nonspecific clinical symptoms and radiographic features that can resemble other gastrointestinal conditions, creating diagnostic uncertainty.\"},{\"question\":\"What diagnostic steps confirmed the coexistence of colorectal cancer and chronic Schistosoma japonicum infection?\",\"answer\":\"Colonoscopy findings were followed by CT and endoscopic ultrasonography, and endoscopic submucosal dissection provided tissue for histopathology, which showed both adenocarcinoma and extensive egg deposition.\"},{\"question\":\"What clinical message does the case report emphasize for patients from endemic regions?\",\"answer\":\"Clinicians should maintain a high index of suspicion for schistosomiasis when gastrointestinal symptoms occur, using detailed medical histories and appropriate screening to reduce misdiagnosis risk.\"}]","Colorectal Cancer Complicated with Chronic Schistosoma Japonicum Infected - A Case Report | PDF",1789999799,13]